ID   Q4KAS3_PSEF5            Unreviewed;       536 AA.
AC   Q4KAS3;
DT   02-AUG-2005, integrated into UniProtKB/TrEMBL.
DT   02-AUG-2005, sequence version 1.
DT   02-SEP-2026, entry version 115.
DE   SubName: Full=Transcriptional regulator, GntR family/amidohydrolase family protein {ECO:0000313|EMBL:AAY92824.1};
GN   OrderedLocusNames=PFL_3557 {ECO:0000313|EMBL:AAY92824.1};
OS   Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5).
OC   Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
OC   Pseudomonadales; Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=220664 {ECO:0000313|EMBL:AAY92824.1, ECO:0000313|Proteomes:UP000008540};
RN   [1] {ECO:0000313|EMBL:AAY92824.1, ECO:0000313|Proteomes:UP000008540}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-477 / NRRL B-23932 / Pf-5
RC   {ECO:0000313|Proteomes:UP000008540};
RX   PubMed=15980861; DOI=10.1038/nbt1110;
RA   Paulsen I.T., Press C.M., Ravel J., Kobayashi D.Y., Myers G.S.,
RA   Mavrodi D.V., DeBoy R.T., Seshadri R., Ren Q., Madupu R., Dodson R.J.,
RA   Durkin A.S., Brinkac L.M., Daugherty S.C., Sullivan S.A., Rosovitz M.J.,
RA   Gwinn M.L., Zhou L., Schneider D.J., Cartinhour S.W., Nelson W.C.,
RA   Weidman J., Watkins K., Tran K., Khouri H., Pierson E.A., Pierson L.S.III.,
RA   Thomashow L.S., Loper J.E.;
RT   "Complete genome sequence of the plant commensal Pseudomonas fluorescens
RT   Pf-5.";
RL   Nat. Biotechnol. 23:873-878(2005).
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DR   EMBL; CP000076; AAY92824.1; -; Genomic_DNA.
DR   RefSeq; WP_011061836.1; NC_004129.6.
DR   AlphaFoldDB; Q4KAS3; -.
DR   STRING; 220664.PFL_3557; -.
DR   DNASU; 3475376; -.
DR   KEGG; pfl:PFL_3557; -.
DR   PATRIC; fig|220664.5.peg.3636; -.
DR   eggNOG; COG2186; Bacteria.
DR   eggNOG; COG3618; Bacteria.
DR   HOGENOM; CLU_562420_0_0_6; -.
DR   Proteomes; UP000008540; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   CDD; cd01311; PDC_hydrolase; 1.
DR   CDD; cd07377; WHTH_GntR; 1.
DR   Gene3D; 1.20.120.530; GntR ligand-binding domain-like; 1.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR006680; Amidohydro-rel.
DR   InterPro; IPR052358; Aro_Compnd_Degr_Hydrolases.
DR   InterPro; IPR047874; GLI/LigI.
DR   InterPro; IPR011711; GntR_C.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   InterPro; IPR008920; TF_FadR/GntR_C.
DR   InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR35563; BARREL METAL-DEPENDENT HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G16240)-RELATED; 1.
DR   PANTHER; PTHR35563:SF2; BARREL METAL-DEPENDENT HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G16240)-RELATED; 1.
DR   Pfam; PF04909; Amidohydro_2; 1.
DR   Pfam; PF07729; FCD; 1.
DR   Pfam; PF00392; GntR; 1.
DR   PRINTS; PR00035; HTHGNTR.
DR   SMART; SM00895; FCD; 1.
DR   SMART; SM00345; HTH_GNTR; 1.
DR   SUPFAM; SSF48008; GntR ligand-binding domain-like; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50949; HTH_GNTR; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU00307}; Reference proteome {ECO:0000313|Proteomes:UP000008540};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|PROSITE-
KW   ProRule:PRU00307};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW   ECO:0000256|PROSITE-ProRule:PRU00307}.
FT   DOMAIN          10..78
FT                   /note="HTH gntR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50949"
FT   DNA_BIND        38..57
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00307"
SQ   SEQUENCE   536 AA;  59548 MW;  7315E9546CCA16C3 CRC64;
     MTIKAIGRRD HFSVEIFRHL ESEIREGRLR PGDRIPTESR LAEAFAVSRN VVREAVARLN
     SAGLVVSRQG LGVFVATEAN QSSFRITQEE LTDSTKLRQL YELRLDLEVA AAAMAARRRS
     LSQLNKIEAA LDTLRASIQN RQDMVEHSLQ FKRAIADATG NEYFRNFIIF LCSHVYEAAL
     LENHLVRSSD LGETLLAEHQ AIFEAIRLGD PDLARRVTWQ QIINSAERNG LRGLQGWEIT
     RMSSLGETYA PQCAGPAPEP RTLPRTLPDG ACDCHFHVFG DENGQPFSPH RSYTPPPAPL
     EAFQRVQKTL GLSRGVIVQP SVYGADNSTT LAALKEAGSA FRGVVVIDAD TDTETLWAMH
     RLGVRGVRVN LIFKSGVEVS DVAALAEKVA PLGWHLQLLI DITEFADLYE TVASLPVAVV
     IDHMGHMPTS CGLGHPGFTD LLRLLKEGRV WVKLSGAYRF TASKDFPYDD VTPYARALIE
     ANPNRLLWAS DWPHPCIPVP MPNDASLLEM LFNWVENDDA LIKQILVDNP AKLYGF
//