ID   Q4FPP6_PELUB            Unreviewed;       711 AA.
AC   Q4FPP6;
DT   30-AUG-2005, integrated into UniProtKB/TrEMBL.
DT   30-AUG-2005, sequence version 1.
DT   02-APR-2025, entry version 105.
DE   RecName: Full=Ammonium transporter {ECO:0000256|RuleBase:RU362002};
GN   OrderedLocusNames=SAR11_0049 {ECO:0000313|EMBL:AAZ20874.1};
OS   Pelagibacter ubique (strain HTCC1062).
OC   Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria;
OC   Candidatus Pelagibacterales; Candidatus Pelagibacteraceae;
OC   Candidatus Pelagibacter.
OX   NCBI_TaxID=335992 {ECO:0000313|EMBL:AAZ20874.1, ECO:0000313|Proteomes:UP000002528};
RN   [1] {ECO:0000313|EMBL:AAZ20874.1, ECO:0000313|Proteomes:UP000002528}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HTCC1062 {ECO:0000313|EMBL:AAZ20874.1,
RC   ECO:0000313|Proteomes:UP000002528};
RX   PubMed=16109880; DOI=10.1126/science.1114057;
RA   Giovannoni S.J., Tripp H.J., Givan S., Podar M., Vergin K.L., Baptista D.,
RA   Bibbs L., Eads J., Richardson T.H., Noordewier M., Rappe M.S., Short J.M.,
RA   Carrington J.C., Mathur E.J.;
RT   "Genome streamlining in a cosmopolitan oceanic bacterium.";
RL   Science 309:1242-1245(2005).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362002};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU362002}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the ammonia transporter channel (TC 1.A.11.2)
CC       family. {ECO:0000256|ARBA:ARBA00005887, ECO:0000256|RuleBase:RU362002}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000084; AAZ20874.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q4FPP6; -.
DR   STRING; 335992.SAR11_0049; -.
DR   KEGG; pub:SAR11_0049; -.
DR   eggNOG; COG0004; Bacteria.
DR   HOGENOM; CLU_000445_33_6_5; -.
DR   Proteomes; UP000002528; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008519; F:ammonium channel activity; IEA:InterPro.
DR   GO; GO:0097272; P:ammonium homeostasis; IEA:TreeGrafter.
DR   Gene3D; 1.10.3430.10; Ammonium transporter AmtB like domains; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR029020; Ammonium/urea_transptr.
DR   InterPro; IPR001905; Ammonium_transpt.
DR   InterPro; IPR018047; Ammonium_transpt_CS.
DR   InterPro; IPR024041; NH4_transpt_AmtB-like_dom.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   NCBIfam; TIGR00836; amt; 1.
DR   PANTHER; PTHR11730; AMMONIUM TRANSPORTER; 1.
DR   PANTHER; PTHR11730:SF6; AMMONIUM TRANSPORTER; 1.
DR   Pfam; PF00909; Ammonium_transp; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF111352; Ammonium transporter; 1.
DR   PROSITE; PS01219; AMMONIUM_TRANSP; 1.
PE   3: Inferred from homology;
KW   Ammonia transport {ECO:0000256|ARBA:ARBA00023177,
KW   ECO:0000256|RuleBase:RU362002};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002528};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU362002};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU362002};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362002}.
FT   TRANSMEM        12..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        51..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        89..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        119..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        176..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        217..234
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        246..271
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        278..294
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        300..317
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        329..350
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        370..388
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   DOMAIN          495..710
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|SMART:SM00331"
SQ   SEQUENCE   711 AA;  77840 MW;  DA4F69A89EA494C8 CRC64;
     MESVKSFVDT LWVIDCAILV FIMQAGFMCM ETGLSRHKNS INVALKNAAD FGLSVVVFWI
     FGFGLMFGTS YNGFFGTDLF FFKTEKADYM TYFVFQAMFV ATAATIVSGA VAERMKFNGY
     LIITIIATGI IYPIVGHWAW SSSYLNNMND TVMQLSAVTG EIKNTGWLTE LGFVDFAGST
     IVHSVGGWIA LAAVLILGPR IGKYSESNKG KFTGSSFPLA VLGTLILWFG WFGFNGGSNG
     AMDETVPLIL INTFLSAAFG LLTGLGISFL LFKKPDPFYV ILGPLAGLVA ITAGCNSMTS
     VTAIFVGIIG AIVAIFINEL LNKYEIDDVV GAVPVHLGAG VWGTISVGLF SDLEKLGTGL
     TRLEQIEVQV IGILAIGAFA FFGSYIILKI LNYFYPLRVT PLQEELGLNI AEHNAVSVEH
     DLISILEKQS ESGDLSVRGP QDPFTAGGVI GLYYNKLMNK LEVSENEKEK WRSRISKEIN
     LAVKVQENFL PKRDLQNYPV QGINIASREV SGDFFSFYPH NDSINFIIAD VAGKGVHAGM
     VMAKASTLFE VMSRDQVDPD EMMLHMNNDL FLTKTSGMFV TCVLGKYDLI TKEVSWVNAG
     HQPAIIRDKN GKYQNFDSEA PPMGVIHQKN KSIYKINKQV LNGNKFYVFT DGLSESLNAE
     GQEIGIEGSI EIIEDNYTKD SKKHLSDISK KIIDSSKSGK LSDDLTLISI G
//