ID   Q3ZCU6_HUMAN            Unreviewed;       195 AA.
AC   Q3ZCU6;
DT   27-SEP-2005, integrated into UniProtKB/TrEMBL.
DT   27-SEP-2005, sequence version 1.
DT   02-SEP-2026, entry version 91.
DE   SubName: Full=SEL1L protein {ECO:0000313|EMBL:AAH40498.1};
DE   Flags: Fragment;
GN   Name=SEL1L {ECO:0000313|EMBL:AAH40498.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:AAH40498.1};
RN   [1] {ECO:0000313|EMBL:AAH40498.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain {ECO:0000313|EMBL:AAH40498.1};
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RA   Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H.,
RA   Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M.,
RA   Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.,
RA   Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F.,
RA   Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T.,
RA   Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F.,
RA   Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E.,
RA   Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y.,
RA   Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E.,
RA   Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y.,
RA   Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W.,
RA   Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J.,
RA   Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA   Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J.,
RA   Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W.,
RA   Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J.,
RA   Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I.,
RA   Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U.,
RA   Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A.,
RA   Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SIMILARITY: Belongs to the sel-1 family.
CC       {ECO:0000256|ARBA:ARBA00038101}.
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DR   EMBL; BC040498; AAH40498.1; -; mRNA.
DR   RefSeq; NP_005056.3; NM_005065.6.
DR   AlphaFoldDB; Q3ZCU6; -.
DR   SMR; Q3ZCU6; -.
DR   PeptideAtlas; Q3ZCU6; -.
DR   DNASU; 6400; -.
DR   GeneID; 6400; -.
DR   KEGG; hsa:6400; -.
DR   ClinPGx; PA35639; -.
DR   CTD; 6400; -.
DR   DisGeNET; 6400; -.
DR   OrthoDB; 27934at2759; -.
DR   BioGRID-ORCS; 6400; 90 hits in 1160 CRISPR screens.
DR   ChiTaRS; SEL1L; human.
DR   FunFam; 1.25.40.10:FF:000208; Protein sel-1 homolog 1; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   InterPro; IPR006597; Sel1-like.
DR   InterPro; IPR050767; Sel1_AlgK.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR11102:SF70; PROTEIN SEL-1 HOMOLOG 1; 1.
DR   PANTHER; PTHR11102; SEL-1-LIKE PROTEIN; 1.
DR   Pfam; PF08238; Sel1; 3.
DR   SMART; SM00671; SEL1; 2.
DR   SUPFAM; SSF81901; HCP-like; 1.
PE   2: Evidence at transcript level;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        144..162
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          167..195
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        172..195
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AAH40498.1"
SQ   SEQUENCE   195 AA;  22239 MW;  5E61FC72BAEA5471 CRC64;
     SEASIVGENE TYPRALLHWN RAASQGYTVA RIKLGDYHFY GFGTDVDYET AFIHYRLASE
     QQHSAQAMFN LGYMHEKGLG IKQDIHLAKR FYDMAAEASP DAQVPVFLAL CKLGVVYFLQ
     YIRETNIRDM FTQLDMDQLL GPEWDLYLMT IIALLLGTVI AYRQRQHQDM PAPRPPGPRP
     APPQQEGPPE QQPPQ
//