ID   Q39GS1_BURL3            Unreviewed;       612 AA.
AC   Q39GS1;
DT   22-NOV-2005, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2005, sequence version 1.
DT   02-SEP-2026, entry version 99.
DE   SubName: Full=Methyl-accepting chemotaxis sensory transducer {ECO:0000313|EMBL:ABB08345.1};
GN   OrderedLocusNames=Bcep18194_A4750 {ECO:0000313|EMBL:ABB08345.1};
OS   Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 /
OS   R18194 / 383).
OC   Bacteria; Pseudomonadati; Pseudomonadota; Betaproteobacteria;
OC   Burkholderiales; Burkholderiaceae; Burkholderia;
OC   Burkholderia cepacia complex.
OX   NCBI_TaxID=482957 {ECO:0000313|EMBL:ABB08345.1, ECO:0000313|Proteomes:UP000002705};
RN   [1] {ECO:0000313|EMBL:ABB08345.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=383 {ECO:0000313|EMBL:ABB08345.1};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA   Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A.,
RA   Richardson P.;
RT   "Complete sequence of chromosome 1 of Burkholderia sp. 383.";
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004429}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; CP000151; ABB08345.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q39GS1; -.
DR   KEGG; bur:Bcep18194_A4750; -.
DR   PATRIC; fig|482957.22.peg.1669; -.
DR   HOGENOM; CLU_000445_107_16_4; -.
DR   Proteomes; UP000002705; Chromosome 1.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd06225; HAMP; 1.
DR   FunFam; 1.10.287.950:FF:000001; Methyl-accepting chemotaxis sensory transducer; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR035440; 4HB_MCP_dom_sf.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR003122; Tar_rcpt_lig-bd.
DR   PANTHER; PTHR43531:SF14; METHYL-ACCEPTING CHEMOTAXIS PROTEIN I-RELATED; 1.
DR   PANTHER; PTHR43531; PROTEIN ICFG; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   Pfam; PF02203; TarH; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF47170; Aspartate receptor, ligand-binding domain; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Methylation {ECO:0000256|ARBA:ARBA00022481};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002705};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        34..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        213..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          235..287
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          292..521
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   REGION          569..612
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          492..530
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        579..604
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   612 AA;  64388 MW;  DECA1F428B00B93A CRC64;
     MHRVKQCFEA TGLSRPSRRN TGRMMVFKNL TIRARIGFTM AFLAVLLAVI GGLGVYGMTR
     ANDTTRDIFT NQMPSAVDVS VAEIYAARER LALDRAALLA STPDAAAAVE RSRAMRAQSD
     TWWQKYLALP RGPEEDRLAQ DVAAKRQALQ HECDAFASVV GANQADRIGE GAKQLQARYN
     DLATASEALR NFQFTDAQAG FDHAESAYDT LRVLAIVALL AGLGAAVVSW LTLSRAIGRP
     IADALAHFDA IAAGDLRRPI VVDRHDEMGQ LLEGLGKMQR GLVDTVRTVR GGSESIATAA
     RQIAAGNIDL SSRTEEQAAA LQETASSMEQ LTGTVKQNAD NARQASSLAA NASEIANKGN
     TVVGQVVGTM GEINDSSAKI ADIIAIIEGI AFQTNILALN AAVEAARAGE EGRGFAVVAG
     EVRSLAQRSS TAAKEIKVLI DASVERIRSG STLVDEAGRT MSDVIGAVQR VTDIMGEIAA
     ASEEQSGGID QVARAVAQMD EVTQQNAALV EEAAAAAQSL DEQAGRLRET AAVFQLNEDT
     ARPGAAAPVA VRHAPRAPAA AVAVPVQAAA RDERDAPPRR VAAAAPVRKP VAASAAPVQT
     AATADSDDWE TF
//