ID   Q30SW9_SULDN            Unreviewed;       310 AA.
AC   Q30SW9;
DT   06-DEC-2005, integrated into UniProtKB/TrEMBL.
DT   06-DEC-2005, sequence version 1.
DT   04-NOV-2026, entry version 95.
DE   SubName: Full=Radical SAM {ECO:0000313|EMBL:ABB43912.1};
GN   OrderedLocusNames=Suden_0633 {ECO:0000313|EMBL:ABB43912.1};
OS   Sulfurimonas denitrificans (strain ATCC 33889 / DSM 1251) (Thiomicrospira
OS   denitrificans (strain ATCC 33889 / DSM 1251)).
OC   Bacteria; Pseudomonadati; Campylobacterota; Epsilonproteobacteria;
OC   Campylobacterales; Sulfurimonadaceae; Sulfurimonas.
OX   NCBI_TaxID=326298 {ECO:0000313|EMBL:ABB43912.1, ECO:0000313|Proteomes:UP000002714};
RN   [1] {ECO:0000313|EMBL:ABB43912.1, ECO:0000313|Proteomes:UP000002714}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33889 / DSM 1251 {ECO:0000313|Proteomes:UP000002714};
RX   PubMed=18065616; DOI=10.1128/AEM.01844-07;
RA   Sievert S.M., Scott K.M., Klotz M.G., Chain P.S.G., Hauser L.J., Hemp J.,
RA   Huegler M., Land M., Lapidus A., Larimer F.W., Lucas S., Malfatti S.A.,
RA   Meyer F., Paulsen I.T., Ren Q., Simon J., Bailey K., Diaz E.,
RA   Fitzpatrick K.A., Glover B., Gwatney N., Korajkic A., Long A.,
RA   Mobberley J.M., Pantry S.N., Pazder G., Peterson S., Quintanilla J.D.,
RA   Sprinkle R., Stephens J., Thomas P., Vaughn R., Weber M.J., Wooten L.L.;
RT   "Genome of the epsilonproteobacterial chemolithoautotroph Sulfurimonas
RT   denitrificans.";
RL   Appl. Environ. Microbiol. 74:1145-1156(2008).
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966, ECO:0000256|PROSITE-
CC         ProRule:PRU01266};
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DR   EMBL; CP000153; ABB43912.1; -; Genomic_DNA.
DR   RefSeq; WP_011372266.1; NC_007575.1.
DR   AlphaFoldDB; Q30SW9; -.
DR   STRING; 326298.Suden_0633; -.
DR   KEGG; tdn:Suden_0633; -.
DR   eggNOG; COG0731; Bacteria.
DR   HOGENOM; CLU_058377_0_1_7; -.
DR   OMA; AAINCPC; -.
DR   OrthoDB; 9800840at2; -.
DR   Proteomes; UP000002714; Chromosome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR   CDD; cd01335; Radical_SAM; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR   InterPro; IPR040084; GTPase_Obg.
DR   InterPro; IPR007197; rSAM.
DR   InterPro; IPR058240; rSAM_sf.
DR   PANTHER; PTHR43787; FEMO COFACTOR BIOSYNTHESIS PROTEIN NIFB-RELATED; 1.
DR   PANTHER; PTHR43787:SF11; UPF0026 PROTEIN SLR1464; 1.
DR   Pfam; PF04055; Radical_SAM; 1.
DR   SFLD; SFLDS00029; Radical_SAM; 1.
DR   SFLD; SFLDG01067; SPASM/twitch_domain_containing; 1.
DR   SFLD; SFLDG01083; Uncharacterised_Radical_SAM_Su; 1.
DR   SMART; SM00729; Elp3; 1.
DR   SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR   PROSITE; PS51918; RADICAL_SAM; 1.
PE   4: Predicted;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485, ECO:0000256|PROSITE-
KW   ProRule:PRU01266};
KW   Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PROSITE-ProRule:PRU01266};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014, ECO:0000256|PROSITE-
KW   ProRule:PRU01266};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW   ProRule:PRU01266}; Reference proteome {ECO:0000313|Proteomes:UP000002714};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW   ECO:0000256|PROSITE-ProRule:PRU01266}.
FT   DOMAIN          13..241
FT                   /note="Radical SAM core"
FT                   /evidence="ECO:0000259|PROSITE:PS51918"
FT   BINDING         28
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01266"
FT   BINDING         32
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01266"
FT   BINDING         35
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01266"
SQ   SEQUENCE   310 AA;  35482 MW;  547DAF54C25F315D CRC64;
     MKTIFGPINS RRFGSSLGVD LSPALKQCNF DCLYCELAPS ATTDKQIEVV EVSTIIDELK
     THLHDKIDVI TLTANGEPTL YPHLDKLIEE IDKIKNSTQT LILTNSATLV DDRIFSLLLK
     LDQVKLSLDA VSDNVFKRID RPHKNIDIAK IVQKVEEFSH VYRGKLFIEI LFVHGLNDTK
     EEIYKLNEVL LKINATRIDL GTIDRPPAYP VEGLSYKELY EVSLLFDSSL PVHVASRIHA
     EPNNATYDDE EILNTLDKRP LTMEDIDLLF DEESKIRLKN LMSKKIVVIK KIGNLEFFIL
     HENEKRKRIK
//