ID   Q2SWV5_BURTA            Unreviewed;       170 AA.
AC   Q2SWV5;
DT   24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT   24-JAN-2006, sequence version 1.
DT   28-JAN-2026, entry version 110.
DE   RecName: Full=Ureidoglycolate lyase {ECO:0000256|HAMAP-Rule:MF_00616};
DE            EC=4.3.2.3 {ECO:0000256|HAMAP-Rule:MF_00616};
DE   AltName: Full=Ureidoglycolatase {ECO:0000256|HAMAP-Rule:MF_00616};
GN   Name=allA {ECO:0000256|HAMAP-Rule:MF_00616};
GN   OrderedLocusNames=BTH_I2070 {ECO:0000313|EMBL:ABC37170.1};
OS   Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CCUG 48851 /
OS   CIP 106301 / E264).
OC   Bacteria; Pseudomonadati; Pseudomonadota; Betaproteobacteria;
OC   Burkholderiales; Burkholderiaceae; Burkholderia; pseudomallei group.
OX   NCBI_TaxID=271848 {ECO:0000313|EMBL:ABC37170.1, ECO:0000313|Proteomes:UP000001930};
RN   [1] {ECO:0000313|EMBL:ABC37170.1, ECO:0000313|Proteomes:UP000001930}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700388 / DSM 13276 / CCUG 48851 / CIP 106301 / E264
RC   {ECO:0000313|Proteomes:UP000001930};
RX   PubMed=16336651; DOI=10.1186/1471-2164-6-174;
RA   Kim H.S., Schell M.A., Yu Y., Ulrich R.L., Sarria S.H., Nierman W.C.,
RA   DeShazer D.;
RT   "Bacterial genome adaptation to niches: divergence of the potential
RT   virulence genes in three Burkholderia species of different survival
RT   strategies.";
RL   BMC Genomics 6:174-174(2005).
CC   -!- FUNCTION: Catalyzes the catabolism of the allantoin degradation
CC       intermediate (S)-ureidoglycolate, generating urea and glyoxylate.
CC       Involved in the utilization of allantoin as nitrogen source.
CC       {ECO:0000256|HAMAP-Rule:MF_00616}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-ureidoglycolate = urea + glyoxylate; Xref=Rhea:RHEA:11304,
CC         ChEBI:CHEBI:16199, ChEBI:CHEBI:36655, ChEBI:CHEBI:57296; EC=4.3.2.3;
CC         Evidence={ECO:0000256|ARBA:ARBA00047684, ECO:0000256|HAMAP-
CC         Rule:MF_00616};
CC   -!- COFACTOR:
CC       Name=Ni(2+); Xref=ChEBI:CHEBI:49786; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_00616};
CC   -!- PATHWAY: Nitrogen metabolism; (S)-allantoin degradation.
CC       {ECO:0000256|HAMAP-Rule:MF_00616}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738, ECO:0000256|HAMAP-
CC       Rule:MF_00616}.
CC   -!- SIMILARITY: Belongs to the ureidoglycolate lyase family.
CC       {ECO:0000256|HAMAP-Rule:MF_00616}.
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DR   EMBL; CP000086; ABC37170.1; -; Genomic_DNA.
DR   RefSeq; WP_009890510.1; NC_007651.1.
DR   AlphaFoldDB; Q2SWV5; -.
DR   GeneID; 45121798; -.
DR   KEGG; bte:BTH_I2070; -.
DR   HOGENOM; CLU_070848_1_0_4; -.
DR   UniPathway; UPA00395; -.
DR   Proteomes; UP000001930; Chromosome I.
DR   GO; GO:0004848; F:ureidoglycolate hydrolase activity; IEA:InterPro.
DR   GO; GO:0050385; F:ureidoglycolate lyase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0000256; P:allantoin catabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006145; P:purine nucleobase catabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd20298; cupin_UAH; 1.
DR   Gene3D; 2.60.120.480; Ureidoglycolate hydrolase; 1.
DR   HAMAP; MF_00616; Ureidogly_lyase; 1.
DR   InterPro; IPR011051; RmlC_Cupin_sf.
DR   InterPro; IPR047233; UAH_cupin.
DR   InterPro; IPR007247; Ureidogly_lyase.
DR   InterPro; IPR023525; Ureidogly_lyase_bac.
DR   InterPro; IPR024060; Ureidoglycolate_lyase_dom_sf.
DR   NCBIfam; NF002950; PRK03606.1-3; 1.
DR   NCBIfam; NF009932; PRK13395.1; 1.
DR   PANTHER; PTHR21221; UREIDOGLYCOLATE HYDROLASE; 1.
DR   PANTHER; PTHR21221:SF1; UREIDOGLYCOLATE LYASE; 1.
DR   Pfam; PF04115; Ureidogly_lyase; 1.
DR   PIRSF; PIRSF017306; Ureidogly_hydro; 1.
DR   SUPFAM; SSF51182; RmlC-like cupins; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000313|EMBL:ABC37170.1};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|HAMAP-Rule:MF_00616};
KW   Purine metabolism {ECO:0000256|ARBA:ARBA00022631, ECO:0000256|HAMAP-
KW   Rule:MF_00616}; Reference proteome {ECO:0000313|Proteomes:UP000001930}.
SQ   SEQUENCE   170 AA;  18159 MW;  EA6712247EA431D6 CRC64;
     MNTLAIEPLT RAAFAPFGDV IETAGAKQIP INLGTTVRFH DLARIDVADE GGRPLVNLFR
     GQPRTLPFEV TMLERHPLGS QAFIPLTDRP YIVVVAPAGV LDPPKIRAFV TSGWQGVNYA
     KGVWHHPLIA LGGVSDFIVV DRGGGGGNLD EQDLAGSLWL TEDALLAVSA
//