ID Q2SKW0_HAHCH Unreviewed; 332 AA. AC Q2SKW0; DT 24-JAN-2006, integrated into UniProtKB/TrEMBL. DT 24-JAN-2006, sequence version 1. DT 04-NOV-2026, entry version 114. DE RecName: Full=RNA polymerase sigma factor RpoS {ECO:0000256|HAMAP-Rule:MF_00959}; DE AltName: Full=Sigma S {ECO:0000256|HAMAP-Rule:MF_00959}; DE AltName: Full=Sigma-38 {ECO:0000256|HAMAP-Rule:MF_00959}; GN Name=rpoS {ECO:0000256|HAMAP-Rule:MF_00959, GN ECO:0000313|EMBL:ABC28714.1}; GN OrderedLocusNames=HCH_01877 {ECO:0000313|EMBL:ABC28714.1}; OS Hahella chejuensis (strain KCTC 2396). OC Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; OC Oceanospirillales; Hahellaceae; Hahella. OX NCBI_TaxID=349521 {ECO:0000313|EMBL:ABC28714.1, ECO:0000313|Proteomes:UP000000238}; RN [1] {ECO:0000313|EMBL:ABC28714.1, ECO:0000313|Proteomes:UP000000238} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=KCTC 2396 {ECO:0000313|EMBL:ABC28714.1, RC ECO:0000313|Proteomes:UP000000238}; RX PubMed=16352867; DOI=10.1093/nar/gki1016; RA Jeong H., Yim J.H., Lee C., Choi S.-H., Park Y.K., Yoon S.H., Hur C.-G., RA Kang H.-Y., Kim D., Lee H.H., Park K.H., Park S.-H., Park H.-S., Lee H.K., RA Oh T.K., Kim J.F.; RT "Genomic blueprint of Hahella chejuensis, a marine microbe producing an RT algicidal agent."; RL Nucleic Acids Res. 33:7066-7073(2005). CC -!- FUNCTION: Sigma factors are initiation factors that promote the CC attachment of RNA polymerase to specific initiation sites and are then CC released. This sigma factor is the master transcriptional regulator of CC the stationary phase and the general stress response. CC {ECO:0000256|HAMAP-Rule:MF_00959}. CC -!- SUBUNIT: Interacts with the RNA polymerase core enzyme. CC {ECO:0000256|HAMAP-Rule:MF_00959}. CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00959}. CC -!- SIMILARITY: Belongs to the sigma-70 factor family. RpoS subfamily. CC {ECO:0000256|HAMAP-Rule:MF_00959}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CP000155; ABC28714.1; -; Genomic_DNA. DR RefSeq; WP_011395785.1; NC_007645.1. DR AlphaFoldDB; Q2SKW0; -. DR STRING; 349521.HCH_01877; -. DR KEGG; hch:HCH_01877; -. DR eggNOG; COG0568; Bacteria. DR HOGENOM; CLU_014793_3_5_6; -. DR OMA; AAKFRHY; -. DR OrthoDB; 9809557at2; -. DR Proteomes; UP000000238; Chromosome. DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule. DR GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-UniRule. DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:UniProtKB-UniRule. DR CDD; cd06171; Sigma70_r4; 1. DR FunFam; 1.10.601.10:FF:000001; RNA polymerase sigma factor SigA; 1. DR Gene3D; 1.10.601.10; RNA Polymerase Primary Sigma Factor; 1. DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2. DR HAMAP; MF_00959; Sigma70_RpoS; 1. DR InterPro; IPR014284; RNA_pol_sigma-70_dom. DR InterPro; IPR000943; RNA_pol_sigma70. DR InterPro; IPR009042; RNA_pol_sigma70_r1_2. DR InterPro; IPR007627; RNA_pol_sigma70_r2. DR InterPro; IPR007624; RNA_pol_sigma70_r3. DR InterPro; IPR007630; RNA_pol_sigma70_r4. DR InterPro; IPR013325; RNA_pol_sigma_r2. DR InterPro; IPR013324; RNA_pol_sigma_r3/r4-like. DR InterPro; IPR012761; RNA_pol_sigma_RpoS. DR InterPro; IPR050239; Sigma-70_RNA_pol_init_factors. DR InterPro; IPR036388; WH-like_DNA-bd_sf. DR NCBIfam; NF004207; rpoS; 1. DR NCBIfam; TIGR02394; rpoS_proteo; 1. DR NCBIfam; TIGR02937; sigma70-ECF; 1. DR PANTHER; PTHR30603; RNA POLYMERASE SIGMA FACTOR RPO; 1. DR PANTHER; PTHR30603:SF67; RNA POLYMERASE SIGMA FACTOR RPOS; 1. DR Pfam; PF00140; Sigma70_r1_2; 1. DR Pfam; PF04542; Sigma70_r2; 1. DR Pfam; PF04539; Sigma70_r3; 1. DR Pfam; PF04545; Sigma70_r4; 1. DR PRINTS; PR00046; SIGMA70FCT. DR SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1. DR SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 2. DR PROSITE; PS00715; SIGMA70_1; 1. DR PROSITE; PS00716; SIGMA70_2; 1. PE 3: Inferred from homology; KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_00959}; KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP- KW Rule:MF_00959}; Reference proteome {ECO:0000313|Proteomes:UP000000238}; KW Sigma factor {ECO:0000256|ARBA:ARBA00023082, ECO:0000256|HAMAP- KW Rule:MF_00959}; KW Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP- KW Rule:MF_00959}; KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015, ECO:0000256|HAMAP- KW Rule:MF_00959}. FT DOMAIN 121..134 FT /note="RNA polymerase sigma-70" FT /evidence="ECO:0000259|PROSITE:PS00715" FT DOMAIN 290..316 FT /note="RNA polymerase sigma-70" FT /evidence="ECO:0000259|PROSITE:PS00716" FT DNA_BIND 291..310 FT /note="H-T-H motif" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00959" FT REGION 59..92 FT /note="Sigma-70 factor domain-1" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00959" FT REGION 97..167 FT /note="Sigma-70 factor domain-2" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00959" FT REGION 177..252 FT /note="Sigma-70 factor domain-3" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00959" FT REGION 265..318 FT /note="Sigma-70 factor domain-4" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00959" FT MOTIF 121..124 FT /note="Interaction with polymerase core subunit RpoC" FT /evidence="ECO:0000256|HAMAP-Rule:MF_00959" SQ SEQUENCE 332 AA; 38057 MW; CBBC49CCC2DF286E CRC64; MAAERESYAE DLAYDVDIDL AEIEAEEFED DESDVVVSID QGRTGRFSLG EGQSYRNLDA TQIYLNEIGF SPLLTPEEEV HFARMARRGD EKGRKRMIES NLRLVVKIAR RYVNRGLSLL DLIEEGNLGL IRAVEKFDPE RGFRFSTYAT WWIRQTIERA IMNQTRTIRL PIHVVKELNV YLRASRELTQ KLDHEPSAEE IADLLEKPVK DVKRMLGLNE RITSVDSPIG GNAEKSLLDT VADEASNDPA ELLQDSDLKG CLDRWLDQLS DKQQEVIARR FGLRGYPMST LEEVGQEIGL TRERVRQIQV EALKRMRELL EKEGLTGDTL FK //