ID   Q2SDT4_HAHCH            Unreviewed;       442 AA.
AC   Q2SDT4;
DT   24-JAN-2006, integrated into UniProtKB/TrEMBL.
DT   24-JAN-2006, sequence version 1.
DT   02-SEP-2026, entry version 94.
DE   SubName: Full=Adenylate cyclase, family 3 {ECO:0000313|EMBL:ABC31190.1};
GN   OrderedLocusNames=HCH_04487 {ECO:0000313|EMBL:ABC31190.1};
OS   Hahella chejuensis (strain KCTC 2396).
OC   Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
OC   Oceanospirillales; Hahellaceae; Hahella.
OX   NCBI_TaxID=349521 {ECO:0000313|EMBL:ABC31190.1, ECO:0000313|Proteomes:UP000000238};
RN   [1] {ECO:0000313|EMBL:ABC31190.1, ECO:0000313|Proteomes:UP000000238}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KCTC 2396 {ECO:0000313|EMBL:ABC31190.1,
RC   ECO:0000313|Proteomes:UP000000238};
RX   PubMed=16352867; DOI=10.1093/nar/gki1016;
RA   Jeong H., Yim J.H., Lee C., Choi S.-H., Park Y.K., Yoon S.H., Hur C.-G.,
RA   Kang H.-Y., Kim D., Lee H.H., Park K.H., Park S.-H., Park H.-S., Lee H.K.,
RA   Oh T.K., Kim J.F.;
RT   "Genomic blueprint of Hahella chejuensis, a marine microbe producing an
RT   algicidal agent.";
RL   Nucleic Acids Res. 33:7066-7073(2005).
CC   -!- SIMILARITY: Belongs to the adenylyl cyclase class-4/guanylyl cyclase
CC       family. {ECO:0000256|PROSITE-ProRule:PRU00099}.
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DR   EMBL; CP000155; ABC31190.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q2SDT4; -.
DR   STRING; 349521.HCH_04487; -.
DR   KEGG; hch:HCH_04487; -.
DR   eggNOG; COG2114; Bacteria.
DR   HOGENOM; CLU_047397_0_0_6; -.
DR   Proteomes; UP000000238; Chromosome.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProtKB-ARBA.
DR   GO; GO:0006171; P:cAMP biosynthetic process; IEA:TreeGrafter.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   FunFam; 3.30.70.1230:FF:000025; Adenylate cyclase 1; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR050697; Adenylyl/Guanylyl_Cyclase_3/4.
DR   InterPro; IPR007894; MASE2.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   PANTHER; PTHR43081:SF18; BLL7624 PROTEIN; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   Pfam; PF05230; MASE2; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   3: Inferred from homology;
KW   Magnesium {ECO:0000256|PROSITE-ProRule:PRU00099};
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00099};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000238}.
FT   DOMAIN          212..347
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
FT   BINDING         217
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_label="1"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00099"
FT   BINDING         217
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_label="2"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00099"
FT   BINDING         218
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_label="2"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00099"
FT   BINDING         261
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_label="1"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00099"
FT   BINDING         261
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_label="2"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00099"
SQ   SEQUENCE   442 AA;  49606 MW;  2EBB9822CE620263 CRC64;
     MPDYNARVLG YLVCAAIIVA GILEGHFDEY LIWIIPGAML WPHILYFALR FFDKQKNTKV
     RQGMMVVDGF LCGVILVLIK FSVTPTLFFL LMLNFSFIIV GGMKSWLYGN IAFLAGFTVA
     SIYFGLSFAP PTPMVVSIIG GVTCSLYVGV TAYYTHQQAR ALVQAKSQIQ FQREQSIALS
     HKLAKYLSPQ VWQSIFTGER DVRLETQRKR LAVFFSDIKG FTELAEEMEP ESLTELLNTY
     FNEMSQIALK YGGTIDKFVG DSIMIFFGDP SSRGAKEDTC ACVMMAIEMR KHMKILRQKW
     RSQGVRTPLE IRMGISTGYC TVGNFGAENR MDYTIIGKEV NLASRLESMA APGEILVSYE
     TFALIKDTIM CRDKGEITVK GFAKPVPIYS VVDLRRDIGG NQSFIEHETE GFAMYLDAGK
     VSAQAKERIL KSLESAAEKL RN
//