ID   Q2NFC2_METST            Unreviewed;       180 AA.
AC   Q2NFC2;
DT   07-FEB-2006, integrated into UniProtKB/TrEMBL.
DT   07-FEB-2006, sequence version 1.
DT   28-JAN-2026, entry version 85.
DE   SubName: Full=Predicted adenylate cyclase {ECO:0000313|EMBL:ABC57481.1};
DE            EC=4.6.1.1 {ECO:0000313|EMBL:ABC57481.1};
GN   OrderedLocusNames=Msp_1098 {ECO:0000313|EMBL:ABC57481.1};
OS   Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 /
OS   MCB-3).
OC   Archaea; Methanobacteriati; Methanobacteriota; Methanomada group;
OC   Methanobacteria; Methanobacteriales; Methanobacteriaceae; Methanosphaera.
OX   NCBI_TaxID=339860 {ECO:0000313|EMBL:ABC57481.1, ECO:0000313|Proteomes:UP000001931};
RN   [1] {ECO:0000313|EMBL:ABC57481.1, ECO:0000313|Proteomes:UP000001931}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3
RC   {ECO:0000313|Proteomes:UP000001931};
RX   PubMed=16385054; DOI=10.1128/JB.188.2.642-658.2006;
RA   Fricke W.F., Seedorf H., Henne A., Kruer M., Liesegang H., Hedderich R.,
RA   Gottschalk G., Thauer R.K.;
RT   "The genome sequence of Methanosphaera stadtmanae reveals why this human
RT   intestinal archaeon is restricted to methanol and H2 for methane formation
RT   and ATP synthesis.";
RL   J. Bacteriol. 188:642-658(2006).
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DR   EMBL; CP000102; ABC57481.1; -; Genomic_DNA.
DR   RefSeq; WP_011406680.1; NC_007681.1.
DR   AlphaFoldDB; Q2NFC2; -.
DR   STRING; 339860.Msp_1098; -.
DR   GeneID; 3856089; -.
DR   KEGG; mst:Msp_1098; -.
DR   eggNOG; arCOG01723; Archaea.
DR   HOGENOM; CLU_105244_2_0_2; -.
DR   OrthoDB; 46040at2157; -.
DR   Proteomes; UP000001931; Chromosome.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProtKB-EC.
DR   CDD; cd07890; CYTH-like_AC_IV-like; 1.
DR   Gene3D; 2.40.320.10; Hypothetical Protein Pfu-838710-001; 1.
DR   InterPro; IPR008173; Adenylyl_cyclase_CyaB.
DR   InterPro; IPR033469; CYTH-like_dom_sf.
DR   InterPro; IPR023577; CYTH_domain.
DR   NCBIfam; TIGR00318; cyaB; 1.
DR   PANTHER; PTHR21028:SF2; CYTH DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR21028; SI:CH211-156B7.4; 1.
DR   Pfam; PF01928; CYTH; 1.
DR   SMART; SM01118; CYTH; 1.
DR   SUPFAM; SSF55154; CYTH-like phosphatases; 1.
DR   PROSITE; PS51707; CYTH; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000313|EMBL:ABC57481.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001931}.
FT   DOMAIN          1..178
FT                   /note="CYTH"
FT                   /evidence="ECO:0000259|PROSITE:PS51707"
SQ   SEQUENCE   180 AA;  21417 MW;  A8A780637377C052 CRC64;
     MIEVEMKAKI NNNKEAFEKI KEIGGEYSHT EKQHDIYFNA PNKDYKETDE ALRIREIPRD
     DDFERILTYK GPKLDSKSKT RKEVEVNIDD TDNMVEILKS LGFKPSAVVN KIRRIFNYDK
     YTITIDKLNR LGYYMEIEYV ANKDEDIEEI RNNIIKVFEK LEITSGFERT SYLELLEQKE
//