ID   Q2KAX2_RHIEC            Unreviewed;       299 AA.
AC   Q2KAX2;
DT   07-MAR-2006, integrated into UniProtKB/TrEMBL.
DT   07-MAR-2006, sequence version 1.
DT   08-OCT-2025, entry version 107.
DE   SubName: Full=Probable myo-inositol 2-dehydrogenase protein {ECO:0000313|EMBL:ABC90014.1};
DE            EC=1.1.1.18 {ECO:0000313|EMBL:ABC90014.1};
GN   OrderedLocusNames=RHE_CH01209 {ECO:0000313|EMBL:ABC90014.1};
OS   Rhizobium etli (strain ATCC 51251 / DSM 11541 / JCM 21823 / NBRC 15573 /
OS   CFN 42).
OC   Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria;
OC   Hyphomicrobiales; Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=347834 {ECO:0000313|EMBL:ABC90014.1, ECO:0000313|Proteomes:UP000001936};
RN   [1] {ECO:0000313|EMBL:ABC90014.1, ECO:0000313|Proteomes:UP000001936}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51251 / DSM 11541 / JCM 21823 / NBRC 15573 / CFN 42
RC   {ECO:0000313|Proteomes:UP000001936};
RX   PubMed=16505379; DOI=10.1073/pnas.0508502103;
RA   Gonzalez V., Santamaria R.I., Bustos P., Hernandez-Gonzalez I.,
RA   Medrano-Soto A., Moreno-Hagelsieb G., Janga S.C., Ramirez M.A.,
RA   Jimenez-Jacinto V., Collado-Vides J., Davila G.;
RT   "The partitioned Rhizobium etli genome: genetic and metabolic redundancy in
RT   seven interacting replicons.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:3834-3839(2006).
CC   -!- SIMILARITY: Belongs to the Gfo/Idh/MocA family.
CC       {ECO:0000256|ARBA:ARBA00010928}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000133; ABC90014.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q2KAX2; -.
DR   KEGG; ret:RHE_CH01209; -.
DR   eggNOG; COG0673; Bacteria.
DR   HOGENOM; CLU_023194_0_1_5; -.
DR   Proteomes; UP000001936; Chromosome.
DR   GO; GO:0050112; F:inositol 2-dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   Gene3D; 3.30.360.10; Dihydrodipicolinate Reductase, domain 2; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR   InterPro; IPR055170; GFO_IDH_MocA-like_dom.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR42840:SF3; BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10240)-RELATED; 1.
DR   PANTHER; PTHR42840; NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED; 1.
DR   Pfam; PF01408; GFO_IDH_MocA; 1.
DR   Pfam; PF22725; GFO_IDH_MocA_C3; 1.
DR   SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000313|EMBL:ABC90014.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001936}.
FT   DOMAIN          3..84
FT                   /note="Gfo/Idh/MocA-like oxidoreductase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01408"
FT   DOMAIN          97..209
FT                   /note="GFO/IDH/MocA-like oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF22725"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   299 AA;  33160 MW;  11FA5CC82AEB3C27 CRC64;
     MDADRARKVA DAYSAHEVDS DPDRVASRPD VDAVIIASPD FTHAPLSLSC IRAGKQALCE
     KPLSQSSNEC LEIMQAEEAA GSKFIMLGFM RRFDQSYVEM KQALERGAIG RALMMHNFHR
     NVATPASDFT GAMAITNSAP HEFDVVRHVL DTEYVSVSAF QPKRSDALVA PVYMVLETAD
     DQLVNIEINN NAAYGYDVRA ELVGEKATIA MNAVNYTRVD RELGQSTSYE ADWRGRYAEA
     YRRQNRAFVR FVETGVFPHI ASSSWDGYCA ARVAEAGVRA LNDGRKIPVE MIAKPEFYA
//