ID   MRAZ_STAA8              Reviewed;         143 AA.
AC   Q2FZ97;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   04-NOV-2026, entry version 105.
DE   RecName: Full=Transcriptional regulator MraZ;
GN   Name=mraZ {ECO:0000255|HAMAP-Rule:MF_01008};
GN   OrderedLocusNames=SAOUHSC_01142;
OS   Staphylococcus aureus (strain NCTC 8325 / PS 47).
OC   Bacteria; Bacillati; Bacillota; Bacilli; Caryophanales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=93061;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC 8325 / PS 47;
RA   Gillaspy A.F., Worrell V., Orvis J., Roe B.A., Dyer D.W., Iandolo J.J.;
RT   "The Staphylococcus aureus NCTC 8325 genome.";
RL   (In) Fischetti V., Novick R., Ferretti J., Portnoy D., Rood J. (eds.);
RL   Gram positive pathogens, 2nd edition, pp.381-412, ASM Press, Washington
RL   D.C. (2006).
CC   -!- SUBUNIT: Forms oligomers. {ECO:0000255|HAMAP-Rule:MF_01008}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC       Rule:MF_01008}.
CC   -!- SIMILARITY: Belongs to the MraZ family. {ECO:0000255|HAMAP-
CC       Rule:MF_01008}.
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DR   EMBL; CP000253; ABD30252.1; -; Genomic_DNA.
DR   RefSeq; WP_000480800.1; NC_007795.1.
DR   RefSeq; YP_499684.1; NC_007795.1.
DR   AlphaFoldDB; Q2FZ97; -.
DR   SMR; Q2FZ97; -.
DR   STRING; 93061.SAOUHSC_01142; -.
DR   PaxDb; 93061-SAOUHSC_01142; -.
DR   GeneID; 3920702; -.
DR   GeneID; 66839371; -.
DR   KEGG; sao:SAOUHSC_01142; -.
DR   PATRIC; fig|93061.5.peg.1047; -.
DR   eggNOG; COG2001; Bacteria.
DR   HOGENOM; CLU_107907_0_5_9; -.
DR   OMA; AADCELD; -.
DR   OrthoDB; 9807753at2; -.
DR   PHI-base; PHI:11799; -.
DR   PRO; PR:Q2FZ97; -.
DR   Proteomes; UP000008816; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-UniRule.
DR   GO; GO:0009295; C:nucleoid; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR   GO; GO:2000143; P:negative regulation of DNA-templated transcription initiation; IBA:GO_Central.
DR   CDD; cd16321; MraZ_C; 1.
DR   CDD; cd16320; MraZ_N; 1.
DR   FunFam; 3.40.1550.20:FF:000002; Transcriptional regulator MraZ; 1.
DR   Gene3D; 3.40.1550.20; Transcriptional regulator MraZ domain; 1.
DR   HAMAP; MF_01008; MraZ; 1.
DR   InterPro; IPR003444; MraZ.
DR   InterPro; IPR035644; MraZ_C.
DR   InterPro; IPR020603; MraZ_dom.
DR   InterPro; IPR035642; MraZ_N.
DR   InterPro; IPR038619; MraZ_sf.
DR   InterPro; IPR007159; SpoVT-AbrB_dom.
DR   InterPro; IPR037914; SpoVT-AbrB_sf.
DR   NCBIfam; TIGR00242; division/cell wall cluster transcriptional repressor MraZ; 1.
DR   PANTHER; PTHR34701; TRANSCRIPTIONAL REGULATOR MRAZ; 1.
DR   PANTHER; PTHR34701:SF1; TRANSCRIPTIONAL REGULATOR MRAZ; 1.
DR   Pfam; PF02381; MraZ; 2.
DR   SUPFAM; SSF89447; AbrB/MazE/MraZ-like; 1.
DR   PROSITE; PS51740; SPOVT_ABRB; 2.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Reference proteome; Repeat; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..143
FT                   /note="Transcriptional regulator MraZ"
FT                   /id="PRO_1000062944"
FT   DOMAIN          5..47
FT                   /note="SpoVT-AbrB 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01076"
FT   DOMAIN          76..119
FT                   /note="SpoVT-AbrB 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01076"
SQ   SEQUENCE   143 AA;  17238 MW;  40643E518786E699 CRC64;
     MFMGEYDHQL DTKGRMIIPS KFRYDLNERF IITRGLDKCL FGYTLDEWQQ IEEKMKTLPM
     TKKDARKFMR MFFSGAVEVE LDKQGRINIP QNLRKYANLT KECTVIGVSN RIEIWDRETW
     NDFYEESEES FEDIAEDLID FDF
//