ID   Q2FSV6_METHJ            Unreviewed;       631 AA.
AC   Q2FSV6;
DT   21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2006, sequence version 1.
DT   28-JAN-2026, entry version 92.
DE   SubName: Full=Serine phosphatase {ECO:0000313|EMBL:ABD42916.1};
GN   OrderedLocusNames=Mhun_3234 {ECO:0000313|EMBL:ABD42916.1};
OS   Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 /
OS   JF-1).
OC   Archaea; Methanobacteriati; Methanobacteriota; Stenosarchaea group;
OC   Methanomicrobia; Methanomicrobiales; Methanospirillaceae; Methanospirillum.
OX   NCBI_TaxID=323259 {ECO:0000313|EMBL:ABD42916.1, ECO:0000313|Proteomes:UP000001941};
RN   [1] {ECO:0000313|Proteomes:UP000001941}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27890 / DSM 864 / NBRC 100397 / JF-1
RC   {ECO:0000313|Proteomes:UP000001941};
RX   PubMed=26744606; DOI=10.1186/s40793-015-0124-8;
RA   Gunsalus R.P., Cook L.E., Crable B., Rohlin L., McDonald E., Mouttaki H.,
RA   Sieber J.R., Poweleit N., Zhou H., Lapidus A.L., Daligault H.E., Land M.,
RA   Gilna P., Ivanova N., Kyrpides N., Culley D.E., McInerney M.J.;
RT   "Complete genome sequence of Methanospirillum hungatei type strain JF1.";
RL   Stand. Genomic Sci. 11:2-2(2016).
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DR   EMBL; CP000254; ABD42916.1; -; Genomic_DNA.
DR   RefSeq; WP_011450161.1; NC_007796.1.
DR   AlphaFoldDB; Q2FSV6; -.
DR   STRING; 323259.Mhun_3234; -.
DR   EnsemblBacteria; ABD42916; ABD42916; Mhun_3234.
DR   GeneID; 25393615; -.
DR   KEGG; mhu:Mhun_3234; -.
DR   eggNOG; arCOG06893; Archaea.
DR   HOGENOM; CLU_426278_0_0_2; -.
DR   InParanoid; Q2FSV6; -.
DR   OrthoDB; 342253at2157; -.
DR   Proteomes; UP000001941; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0016791; F:phosphatase activity; IEA:TreeGrafter.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd06225; HAMP; 1.
DR   Gene3D; 1.10.8.500; HAMP domain in histidine kinase; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR052016; Bact_Sigma-Reg.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   PANTHER; PTHR43156:SF2; STAGE II SPORULATION PROTEIN E; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF158472; HAMP domain-like; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   PROSITE; PS50885; HAMP; 1.
DR   PROSITE; PS51746; PPM_2; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001941};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        9..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        313..334
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          336..388
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          419..631
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS51746"
FT   COILED          369..396
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   631 AA;  70269 MW;  6D6C595A8736C6C5 CRC64;
     MIVSIRQYLI FYIILIIALV LAGVLPISYI RATEDVIREH AIIEAYTEHT LIESVQLVNK
     GLDLIDSSLN PVMEEMLSTY LEEYTRSGQD PGAMDLFSLK ERFSQQTNAT VDLYVFNEDG
     IILYTTEPAV KGVDFKNYPE FYSALKQHMK GSTPAMDRVV RSVQNQSDLK VLGDLRKFAY
     IPTPDHRYVL EIGLLSDAFA DIRSEFSYQY MVGRIWDENP DIDVLEIYDI WGNRVAVWSS
     DQNISEEVIP LPSDDITQAL RSRSGTSFGS PVQGDRTTIL FIDLKNPQAL SDDSIVAVIR
     YGDRLKEQLE MLLFQYILFG IVGIGSGIIL ALLVSKRISA PIREIVTDVH QIADGDLDHT
     IRSMHTLEFT ELETSMNLMI QKIKEYSEEI ERKRSEMLVA SKIQQSIIPA SFPVPEGFDI
     AAITIPALEV GGDFYDIFSR HDTSVTLVLA DVAGKGVPAA LFMALSRTII RILTRWPGSP
     AGIIRSSNSI FIEDSGSVSF VTLFFGVLDA QSCILRYVNA GHNPPVLYRA ERNLSTLEPT
     GPVIGLLDDP DYSEGSVTLS PGDVLVIYSD GVTEAMDPDG KLFTEERLYE VIQQHHLSSA
     EGLMQAIVLA VRTFAGTAPQ SDDLTLIVVK R
//