Q1LJT9
Q1LJT9_CUPMC
3-deoxy-D-manno-octulosonic acid transferase
Kdo transferase
2.4.99.12
Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase
kdtA
Rmet_2714
Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34)
Ralstonia metallidurans
Bacteria
Pseudomonadati
Pseudomonadota
Betaproteobacteria
Burkholderiales
Burkholderiaceae
Cupriavidus
The complete genome sequence of Cupriavidus metallidurans strain CH34, a master survivalist in harsh and anthropogenic environments.
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
ATCC 43123 / DSM 2839 / NBRC 102507 / CH34
Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.
lipid IVA (E. coli) + CMP-3-deoxy-beta-D-manno-octulosonate = alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP + H(+)
Bacterial outer membrane biogenesis; LPS core biosynthesis.
Cell membrane
Belongs to the glycosyltransferase group 1 family.
Cell membrane
Lipopolysaccharide biosynthesis
Membrane
Reference proteome
Transferase
MLRFVYSLLWLLILPLALLRLVWRSRKESGYIQHVGERLGRYGDLSAAGPWLWVHAVSVGETRAAQPLIDALLAAYPRHRLLLTHMTPTGRQTGAQLYGANPRVQQCYLPYDLPWLVRRFLAYFQPDAGLIMETEVWPNLVHVTRRMGVPLFLVNARLSPRSYRRTARFGGAAAALYNDFTMVLAQTAGDAERYRALGVKSVQVTGNLKFDMQPPEAGVARGQLLRQAFGNRHVLAAASTREGEEPLILEAFSRWPGTDRPALLLVPRHPQRFDEVAAMATRAGFSVQRRSALDIEQLSAPITADVVLGDSMGEMAMYYAASDIAYIGGSLIPLGGQNLIEACAVGTPVLMGPHTFNFAQATEDAIAAGACQRVADADELMVAAAAILGDATRLADMREHALTFAGLHRGATARTLGALAPVLR
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