ID   Q1IXI9_DEIGD            Unreviewed;       636 AA.
AC   Q1IXI9;
DT   13-JUN-2006, integrated into UniProtKB/TrEMBL.
DT   13-JUN-2006, sequence version 1.
DT   04-NOV-2026, entry version 93.
DE   RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE            EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN   OrderedLocusNames=Dgeo_1750 {ECO:0000313|EMBL:ABF46045.1};
OS   Deinococcus geothermalis (strain DSM 11300 / CIP 105573 / AG-3a).
OC   Bacteria; Thermotogati; Deinococcota; Deinococci; Deinococcales;
OC   Deinococcaceae; Deinococcus.
OX   NCBI_TaxID=319795 {ECO:0000313|EMBL:ABF46045.1, ECO:0000313|Proteomes:UP000002431};
RN   [1] {ECO:0000313|EMBL:ABF46045.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=DSM 11300 {ECO:0000313|EMBL:ABF46045.1};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Brettin T., Bruce D., Han C., Tapia R., Saunders E., Gilna P., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Daly M.J.,
RA   Fredrickson J.K., Makarova K.S., Gaidamakova E.K., Zhai M., Richardson P.;
RT   "Complete sequence of chromosome of Deinococcus geothermalis DSM 11300.";
RL   Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC       {ECO:0000256|ARBA:ARBA00006432}.
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DR   EMBL; CP000359; ABF46045.1; -; Genomic_DNA.
DR   RefSeq; WP_011530876.1; NC_008025.1.
DR   AlphaFoldDB; Q1IXI9; -.
DR   STRING; 319795.Dgeo_1750; -.
DR   KEGG; dge:Dgeo_1750; -.
DR   eggNOG; COG0365; Bacteria.
DR   HOGENOM; CLU_000022_3_6_0; -.
DR   OMA; AAIHACY; -.
DR   Proteomes; UP000002431; Chromosome.
DR   GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR   GO; GO:0003987; F:acetyl-CoA synthetase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006085; P:acetyl-CoA biosynthetic process; IEA:TreeGrafter.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR032387; ACAS_N.
DR   InterPro; IPR045851; AMP-b_sf.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_synth/lig_dom.
DR   InterPro; IPR042099; ANL_N_sf.
DR   NCBIfam; NF001208; PRK00174.1; 1.
DR   PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR   PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR   Pfam; PF16177; ACAS_N; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   3: Inferred from homology;
KW   Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ABF46045.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002431}.
FT   DOMAIN          35..78
FT                   /note="Acetyl-coenzyme A synthetase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16177"
FT   DOMAIN          81..458
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          520..598
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
SQ   SEQUENCE   636 AA;  68544 MW;  B7AEB1672DD85AE5 CRC64;
     MDRSLLEHPL VPPTAALKAT APVSEEEAAR LLALDPPAYW LEIARELTWD RPPTVAVEGT
     LGDFRYYPGA TGNVSVNCLD RHPPERTALL YEREDGLRET WTYGELTDAT ARFAAALQDL
     GVAKGDRVAI YLGNVPEAFI AIHACYRIGA IYSVIFAGFS ASAVRDRLTD ARPKVVICTD
     ATLRRGKVIP LKATLDEALE GLEIGHVIVA RRVDRESALR GGEHDFHALL NSTARRADPV
     PLEANEPGFI IYTSGTTSKP KGLVHAGLGF LAGAYANVKW ALNLCPQDVY WCTADVGWLT
     FPIFALVGGL AHGATHVIYE GSIDTPTPAR PYEIIERYGV NKVFTAPTAL RMLRRAGDSA
     LAGHDLNTLE LIALVGEPLD PETWHWTRER LGAGRIFVNN TYGQTETGTA WASSMVGLTP
     TRPGSCGHPL PGYRARVVRE DGQAAAPGEL GALTLTEPFP CLARTVWGDH ERYVQTYLAD
     FPGSYAASDA ALLDGDGQLW VTGRLDDVMN VAGHRIGTME LEAALITHPA VSEAAVVAQP
     DEVKGSVPVA FVVPRGDAQV GPGLEEELAE AIVRGVGPIA RPARVIVTPT VPRTRSGKIM
     RRLLRDLLVS GEVRGDLTSL ENPDAIEVVR ERLAGG
//