Q0T9J7 ULAD_ECOL5 3-keto-L-gulonate-6-phosphate decarboxylase UlaD 4.1.1.85 3-dehydro-L-gulonate-6-phosphate decarboxylase KGPDC L-ascorbate utilization protein D ulaD ECP_4441 Escherichia coli O6:K15:H31 (strain 536 / UPEC) Bacteria Pseudomonadati Pseudomonadota Gammaproteobacteria Enterobacterales Enterobacteriaceae Escherichia NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] 536 / UPEC Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P. Is involved in the anaerobic L-ascorbate utilization. 3-dehydro-L-gulonate 6-phosphate + H(+) = L-xylulose 5-phosphate + CO2 Mg(2+) Binds 1 Mg(2+) ion per subunit. Cofactor degradation; L-ascorbate degradation; D-xylulose 5-phosphate from L-ascorbate: step 2/4. Homodimer. Induced by L-ascorbate. Repressed by UlaR. Belongs to the HPS/KGPDC family. KGPDC subfamily. Carbohydrate metabolism Decarboxylase Lyase Magnesium Metal-binding substrate Mg(2+) Mg(2+) substrate MSLPMLQVALDNQTMDSAYETTRLIAEEVDIIEVGTILCVGEGVRAVRDLKALYPHKIVLADAKIADAGKILSRMCFEANADWVTVICCADINTAKGALDVAKEFNGDVQIELTGYWTWEQAQQWRDAGIGQVVYHRSRDAQAAGVAWGEADITAIKRLSDMGFKVTVTGGLALEDLPLFKGIPIHVFIAGRSIRDAASPVEAARQFKRSIAELWG Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License