ID   Q0AWA3_SYNWW            Unreviewed;       597 AA.
AC   Q0AWA3;
DT   17-OCT-2006, integrated into UniProtKB/TrEMBL.
DT   17-OCT-2006, sequence version 1.
DT   02-SEP-2026, entry version 89.
DE   SubName: Full=Aldehyde ferredoxin oxidoreductase {ECO:0000313|EMBL:ABI69001.1};
DE            EC=1.2.7.5 {ECO:0000313|EMBL:ABI69001.1};
GN   OrderedLocusNames=Swol_1703 {ECO:0000313|EMBL:ABI69001.1};
OS   Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen).
OC   Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales;
OC   Syntrophomonadaceae; Syntrophomonas.
OX   NCBI_TaxID=335541 {ECO:0000313|EMBL:ABI69001.1, ECO:0000313|Proteomes:UP000001968};
RN   [1] {ECO:0000313|Proteomes:UP000001968}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 2245B / Goettingen {ECO:0000313|Proteomes:UP000001968};
RX   PubMed=21966920; DOI=10.1111/j.1462-2920.2010.02237.x;
RA   Sieber J.R., Sims D.R., Han C., Kim E., Lykidis A., Lapidus A.L.,
RA   McDonnald E., Rohlin L., Culley D.E., Gunsalus R., McInerney M.J.;
RT   "The genome of Syntrophomonas wolfei: new insights into syntrophic
RT   metabolism and biohydrogen production.";
RL   Environ. Microbiol. 12:2289-2301(2010).
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
CC   -!- SIMILARITY: Belongs to the AOR/FOR family.
CC       {ECO:0000256|ARBA:ARBA00011032}.
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DR   EMBL; CP000448; ABI69001.1; -; Genomic_DNA.
DR   RefSeq; WP_011641099.1; NC_008346.1.
DR   AlphaFoldDB; Q0AWA3; -.
DR   STRING; 335541.Swol_1703; -.
DR   KEGG; swo:Swol_1703; -.
DR   eggNOG; COG2414; Bacteria.
DR   HOGENOM; CLU_020364_1_0_9; -.
DR   OrthoDB; 9763894at2; -.
DR   Proteomes; UP000001968; Chromosome.
DR   GO; GO:0033726; F:aldehyde ferredoxin oxidoreductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR   Gene3D; 1.10.569.10; Aldehyde Ferredoxin Oxidoreductase Protein, subunit A, domain 2; 1.
DR   Gene3D; 1.10.599.10; Aldehyde Ferredoxin Oxidoreductase Protein, subunit A, domain 3; 1.
DR   Gene3D; 3.60.9.10; Aldehyde ferredoxin oxidoreductase, N-terminal domain; 1.
DR   InterPro; IPR013984; Ald_Fedxn_OxRdtase_dom2.
DR   InterPro; IPR013985; Ald_Fedxn_OxRdtase_dom3.
DR   InterPro; IPR013983; Ald_Fedxn_OxRdtase_N.
DR   InterPro; IPR036503; Ald_Fedxn_OxRdtase_N_sf.
DR   InterPro; IPR001203; OxRdtase_Ald_Fedxn_C.
DR   InterPro; IPR036021; Tungsten_al_ferr_oxy-like_C.
DR   InterPro; IPR051919; W-dependent_AOR.
DR   PANTHER; PTHR30038; ALDEHYDE FERREDOXIN OXIDOREDUCTASE; 1.
DR   PANTHER; PTHR30038:SF0; TUNGSTEN-CONTAINING ALDEHYDE FERREDOXIN OXIDOREDUCTASE; 1.
DR   Pfam; PF01314; AFOR_C; 1.
DR   Pfam; PF02730; AFOR_N; 1.
DR   SMART; SM00790; AFOR_N; 1.
DR   SUPFAM; SSF48310; Aldehyde ferredoxin oxidoreductase, C-terminal domains; 1.
DR   SUPFAM; SSF56228; Aldehyde ferredoxin oxidoreductase, N-terminal domain; 1.
PE   3: Inferred from homology;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000313|EMBL:ABI69001.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001968}.
FT   DOMAIN          4..206
FT                   /note="Aldehyde ferredoxin oxidoreductase N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00790"
SQ   SEQUENCE   597 AA;  64678 MW;  5FAFF2BD2B45474A CRC64;
     MYAWIGQILR VNLTDATIKK EKLDPALLRN YIGARGLGSK LFMDEVNPQV DPLSPENKII
     FMTGPLTGTL AASGGRYNVV TRGPLNGTIA ASNSGGSFGP ELKYAGYDGI IFEGKAEKPV
     YLWINNAEVE LRSAEELWGR NVPETTDMIK QATHEEAKVA CIGPAGEKLV KFACIMNEYN
     RAAGRSGVGA VMGSKNLKAL AVRGTGGIKV ADRQGFMQAI TDARNKLKAH PVTGAGLAAY
     GTNVLVNILN EHGGLPVKNF SEAAVFAKAE NVSGEYQAEH CLVRNKGCFG CSIGCGRVSR
     NRGKYKGIGE GPEYEATWGL GPNLYIDDFE AISKANFLCN ELGLDPISLA GTLACATEMM
     EKGFIPQEKA ELCWGDADML VEMTIKTAYR EGFGDELAEG SYRLAEKYGH PEFSMSVKKQ
     ELPAYDPRGQ QGIGLNYATS NRGGCHVRGY MTSPEVLGIP EKVDPDSTEG KAALLKIFQD
     LTALVDSAGI CLFTTFGQGL PEIAEQLRQA TGLDLSDEEF LLAGERIWNL ERSFNLQAGI
     SSKDDTLPPR LLREPMKGGP HQGNVVRLEL MLPEYYTLRG WDQAGVPTPE KLQELSL
//