ID   Q0ATH2_MARMM            Unreviewed;       324 AA.
AC   Q0ATH2;
DT   17-OCT-2006, integrated into UniProtKB/TrEMBL.
DT   17-OCT-2006, sequence version 1.
DT   10-JUN-2026, entry version 94.
DE   RecName: Full=diguanylate cyclase {ECO:0000256|ARBA:ARBA00012528};
DE            EC=2.7.7.65 {ECO:0000256|ARBA:ARBA00012528};
GN   OrderedLocusNames=Mmar10_0119 {ECO:0000313|EMBL:ABI64415.1};
OS   Maricaulis maris (strain MCS10) (Caulobacter maris).
OC   Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria;
OC   Maricaulales; Maricaulaceae; Maricaulis.
OX   NCBI_TaxID=394221 {ECO:0000313|EMBL:ABI64415.1, ECO:0000313|Proteomes:UP000001964};
RN   [1] {ECO:0000313|EMBL:ABI64415.1, ECO:0000313|Proteomes:UP000001964}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MCS10 {ECO:0000313|EMBL:ABI64415.1,
RC   ECO:0000313|Proteomes:UP000001964};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Saunders E., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Viollier P.,
RA   Stephens C., Richardson P.;
RT   "Complete sequence of Maricaulis maris MCS10.";
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00169}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000449; ABI64415.1; -; Genomic_DNA.
DR   RefSeq; WP_011642062.1; NC_008347.1.
DR   AlphaFoldDB; Q0ATH2; -.
DR   STRING; 394221.Mmar10_0119; -.
DR   KEGG; mmr:Mmar10_0119; -.
DR   eggNOG; COG3706; Bacteria.
DR   HOGENOM; CLU_000445_11_28_5; -.
DR   OrthoDB; 9812260at2; -.
DR   Proteomes; UP000001964; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:TreeGrafter.
DR   GO; GO:0052621; F:diguanylate cyclase activity; IEA:UniProtKB-EC.
DR   GO; GO:0043709; P:cell adhesion involved in single-species biofilm formation; IEA:TreeGrafter.
DR   GO; GO:1902201; P:negative regulation of bacterial-type flagellum-dependent cell motility; IEA:TreeGrafter.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   CDD; cd01949; GGDEF; 1.
DR   FunFam; 3.30.70.270:FF:000001; Diguanylate cyclase domain protein; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR050469; Diguanylate_Cyclase.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR   PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; CheY-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001964}.
FT   DOMAIN          16..132
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000259|PROSITE:PS50110"
FT   DOMAIN          175..311
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
SQ   SEQUENCE   324 AA;  34945 MW;  D5B7549D5A9D2D0E CRC64;
     MNSADFQTDM TSEAISVLIC ESSSVQLRIL SEAVRQAGYS VQTANKAEDA LTLLQMGTVD
     IFLTGIEVGA VSGLEACWSL KANSETESVY TIVITASGED RRLEESLDAG ADDFIRKPVN
     MTELRARLRA ASRLVRMQKQ FKRLAETDAL TGAANRRAFM QYLEIQSQRA TRDDIPLSVV
     MIDLDHFKSV NDTHGHATGD TVLIEAVKSI QACLRDNDML GRLGGEEFCV ILPGAGLFSA
     GIAGERIRAA VEAMTISTDE GVPVPVTASL GVASLTDGDL ISAPDTLLQT ADVALYRAKE
     TGRNKVWLDG ADERDDEASR RQAG
//