ID   P96492_THENE            Unreviewed;       274 AA.
AC   P96492;
DT   01-MAY-1997, integrated into UniProtKB/TrEMBL.
DT   01-JAN-1998, sequence version 2.
DT   02-SEP-2026, entry version 72.
DE   SubName: Full=Endo-1,4-beta-glucanase B {ECO:0000313|EMBL:AAC95060.1};
DE            EC=3.2.1.4 {ECO:0000313|EMBL:AAC95060.1};
GN   Name=celB {ECO:0000313|EMBL:AAC95060.1};
OS   Thermotoga neapolitana.
OC   Bacteria; Thermotogati; Thermotogota; Thermotogae; Thermotogales;
OC   Thermotogaceae; Thermotoga.
OX   NCBI_TaxID=2337 {ECO:0000313|EMBL:AAC95060.1};
RN   [1] {ECO:0000313|EMBL:AAC95060.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=9835561;
RA   Bok J.D., Yernool D.A., Eveleigh D.E.;
RT   "Purification, characterization, and molecular analysis of thermostable
RT   cellulases CelA and CelB from Thermotoga neapolitana.";
RL   Appl. Environ. Microbiol. 64:4774-4781(1998).
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 12 (cellulase H) family.
CC       {ECO:0000256|ARBA:ARBA00005519, ECO:0000256|RuleBase:RU361163}.
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DR   EMBL; U93354; AAC95060.1; -; Genomic_DNA.
DR   AlphaFoldDB; P96492; -.
DR   SMR; P96492; -.
DR   CAZy; GH12; Glycoside Hydrolase Family 12.
DR   OMA; AMETWIT; -.
DR   GO; GO:0008810; F:cellulase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000272; P:polysaccharide catabolic process; IEA:InterPro.
DR   Gene3D; 2.60.120.180; -; 1.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR013319; GH11/12.
DR   InterPro; IPR002594; GH12.
DR   Pfam; PF01670; Glyco_hydro_12; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism {ECO:0000256|RuleBase:RU361163};
KW   Glycosidase {ECO:0000256|RuleBase:RU361163, ECO:0000313|EMBL:AAC95060.1};
KW   Hydrolase {ECO:0000256|RuleBase:RU361163, ECO:0000313|EMBL:AAC95060.1};
KW   Polysaccharide degradation {ECO:0000256|RuleBase:RU361163};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..274
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5030174933"
SQ   SEQUENCE   274 AA;  31752 MW;  6B21C4F8CA7C9AA2 CRC64;
     MRLVVSFLLV VSAFLFSAEV VLTDIGATDI TFKGFPVTME LNFWNVKSYE GETWLKFDGE
     KVQFYADIYN IVLQNPDSWV HGYPEIYYGY KPWAAHNSGT EILPVKVKDL PDFYVTLDYS
     IWYENDLPIN LAMETWITRK PDQTSVSSGD VEIMVWFYNN ILMPGGQKVD EFTTTIEING
     SPVETKWDVY FAPWGWDYLA FRLTTPMKDG RVKFNVKDFV EKAAEVIKKH STRVENFDEM
     YFCVWEIGTE FGDPNTTAAK FGWTFKDFSV EIGE
//