ID   CYSE_STAXY              Reviewed;         216 AA.
AC   P77985;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   02-SEP-2026, entry version 99.
DE   RecName: Full=Serine acetyltransferase;
DE            Short=SAT;
DE            EC=2.3.1.30;
GN   Name=cysE;
OS   Staphylococcus xylosus.
OC   Bacteria; Bacillati; Bacillota; Bacilli; Caryophanales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=1288;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=DSM 20267 / Isolate C2A;
RX   PubMed=9084146; DOI=10.1111/j.1574-6968.1997.tb10286.x;
RA   Fiegler H., Brueckner R.;
RT   "Identification of the serine acetyltransferase gene of Staphylococcus
RT   xylosus.";
RL   FEMS Microbiol. Lett. 148:181-187(1997).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=L-serine + acetyl-CoA = O-acetyl-L-serine + CoA;
CC         Xref=Rhea:RHEA:24560, ChEBI:CHEBI:33384, ChEBI:CHEBI:57287,
CC         ChEBI:CHEBI:57288, ChEBI:CHEBI:58340; EC=2.3.1.30;
CC   -!- PATHWAY: Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine
CC       from L-serine: step 1/2.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the transferase hexapeptide repeat family.
CC       {ECO:0000305}.
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DR   EMBL; Y07614; CAA68887.1; -; Genomic_DNA.
DR   RefSeq; WP_037557109.1; NZ_BKAZ01000049.1.
DR   AlphaFoldDB; P77985; -.
DR   SMR; P77985; -.
DR   STRING; 1288.AWC37_00060; -.
DR   PaxDb; 1288-AWC37_00060; -.
DR   GeneID; 305657173; -.
DR   eggNOG; COG1045; Bacteria.
DR   OrthoDB; 9801456at2; -.
DR   UniPathway; UPA00136; UER00199.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009001; F:L-serine O-acetyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0019344; P:L-cysteine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd03354; LbH_SAT; 1.
DR   FunFam; 1.10.3130.10:FF:000002; Serine acetyltransferase; 1.
DR   FunFam; 2.160.10.10:FF:000007; Serine acetyltransferase; 1.
DR   Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR   Gene3D; 1.10.3130.10; serine acetyltransferase, domain 1; 1.
DR   InterPro; IPR001451; Hexapep.
DR   InterPro; IPR045304; LbH_SAT.
DR   InterPro; IPR042122; Ser_AcTrfase_N_sf.
DR   InterPro; IPR005881; Ser_O-AcTrfase.
DR   InterPro; IPR053376; Serine_acetyltransferase.
DR   InterPro; IPR011004; Trimer_LpxA-like_sf.
DR   NCBIfam; TIGR01172; cysE; 1.
DR   NCBIfam; NF041874; EPS_EpsC; 1.
DR   PANTHER; PTHR42811; SERINE ACETYLTRANSFERASE; 1.
DR   Pfam; PF00132; Hexapep; 1.
DR   PIRSF; PIRSF000441; CysE; 1.
DR   SUPFAM; SSF51161; Trimeric LpxA-like enzymes; 1.
PE   3: Inferred from homology;
KW   Acyltransferase; Amino-acid biosynthesis; Cysteine biosynthesis; Cytoplasm;
KW   Repeat; Transferase.
FT   CHAIN           1..216
FT                   /note="Serine acetyltransferase"
FT                   /id="PRO_0000068685"
SQ   SEQUENCE   216 AA;  24000 MW;  728FE804A0D7282C CRC64;
     MFKFLKRIKD DVNMVFEQDP AARTTLEVIT SYAGVHAVWS HLIAHELYKK KKYVLARLIS
     QVTRFFTGIE IHPGAQIGRR LFIDHGMGVV IGETCRIGDN VTIYQGVTLG GTGKERGKRH
     PDIGDNVLIA AGAKVLGNIT INANVNIGAN SVVLNSVPSY STVVGIPGHI VKQDGRRIGK
     TFDHRNLPDP IYEQLKELEK QLEKTRNGEI QDDYII
//