@base <http://purl.uniprot.org/uniprot/> .
@prefix annotation: <http://purl.uniprot.org/annotation/> .
@prefix citation: <http://purl.uniprot.org/citations/> .
@prefix database: <http://purl.uniprot.org/database/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix disease: <http://purl.uniprot.org/diseases/> .
@prefix ECO: <http://purl.obolibrary.org/obo/ECO_> .
@prefix enzyme: <http://purl.uniprot.org/enzyme/> .
@prefix faldo: <http://biohackathon.org/resource/faldo#> .
@prefix foaf: <http://xmlns.com/foaf/0.1/> .
@prefix go: <http://purl.obolibrary.org/obo/GO_> .
@prefix isoform: <http://purl.uniprot.org/isoforms/> .
@prefix keyword: <http://purl.uniprot.org/keywords/> .
@prefix location: <http://purl.uniprot.org/locations/> .
@prefix obo: <http://purl.obolibrary.org/obo/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix position: <http://purl.uniprot.org/position/> .
@prefix pubmed: <http://purl.uniprot.org/pubmed/> .
@prefix range: <http://purl.uniprot.org/range/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix taxon: <http://purl.uniprot.org/taxonomy/> .
@prefix tissue: <http://purl.uniprot.org/tissues/> .
@prefix up: <http://purl.uniprot.org/core/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
<P77967> a up:Protein ;
  up:reviewed true ;
  up:created "2006-05-16"^^xsd:date ;
  up:modified "2026-09-02"^^xsd:date ;
  up:version 157 ;
  up:mnemonic "CRYD_SYNY3" ;
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    citation:12878596 ,
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    <http://purl.uniprot.org/drugbank/DB03147> ,
    <http://purl.uniprot.org/paxdb/1148-gene:10498633> ,
    <http://rdf.ebi.ac.uk/resource/ensembl.transcript/BAA17766> ,
    <http://purl.uniprot.org/kegg/syn:sll1629> ,
    <http://purl.uniprot.org/eggnog/COG0415> ,
    <http://purl.uniprot.org/inparanoid/P77967> ,
    <http://purl.uniprot.org/phylomedb/P77967> ,
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    <http://purl.uniprot.org/gene3d/1.25.40.80> ,
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    <P77967#SIP6C8C27B572E624BB> ;
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    keyword:157 ,
    keyword:238 ,
    keyword:274 ,
    keyword:1185 ,
    keyword:678 ,
    keyword:805 ,
    go:0003913 ,
    go:0006281 ;
  up:sequence isoform:P77967-1 ;
  up:attribution <P77967#attribution-BCD67FFDCAB6DDEA2C9B27B77B8BED1D> ,
    <P77967#attribution-96CE74A9F3F0C8BB5F9634363907F7B8> ,
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citation:8905231 a up:Journal_Citation ;
  up:title "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." ;
  up:author "Kaneko T." ,
    "Sato S." ,
    "Kotani H." ,
    "Tanaka A." ,
    "Asamizu E." ,
    "Nakamura Y." ,
    "Miyajima N." ,
    "Hirosawa M." ,
    "Sugiura M." ,
    "Sasamoto S." ,
    "Kimura T." ,
    "Hosouchi T." ,
    "Matsuno A." ,
    "Muraki A." ,
    "Nakazaki N." ,
    "Naruo K." ,
    "Okumura S." ,
    "Shimpo S." ,
    "Takeuchi C." ,
    "Wada T." ,
    "Watanabe A." ,
    "Yamada M." ,
    "Yasuda M." ,
    "Tabata S." ;
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  foaf:primaryTopicOf <https://pubmed.ncbi.nlm.nih.gov/8905231> ;
  dcterms:identifier "doi:10.1093/dnares/3.3.109" ;
  up:date "1996"^^xsd:gYear ;
  up:name "DNA Res." ;
  up:volume "3" ;
  up:pages "109-136" .
<#_P77967-citation-8905231> a rdf:Statement ;
  rdf:subject <P77967> ;
  rdf:predicate up:citation ;
  rdf:object citation:8905231 ;
  a up:Citation_Statement ;
  up:scope "NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]" ;
  up:context <P77967#context-MD58B0B37CCBD06FAC38B28AE01EEDA0AB5> .
<P77967#context-MD58B0B37CCBD06FAC38B28AE01EEDA0AB5> a up:Strain ;
  rdfs:label "ATCC 27184 / PCC 6803 / Kazusa" .
citation:10871367 a up:Journal_Citation ;
  up:title "Bacterial cryptochrome and photolyase: characterization of two photolyase-like genes of Synechocystis sp. PCC6803." ;
  up:author "Hitomi K." ,
    "Okamoto K." ,
    "Daiyasu H." ,
    "Miyashita H." ,
    "Iwai S." ,
    "Toh H." ,
    "Ishiura M." ,
    "Todo T." ;
  skos:exactMatch pubmed:10871367 ;
  foaf:primaryTopicOf <https://pubmed.ncbi.nlm.nih.gov/10871367> ;
  dcterms:identifier "doi:10.1093/nar/28.12.2353" ;
  up:date "2000"^^xsd:gYear ;
  up:name "Nucleic Acids Res." ;
  up:volume "28" ;
  up:pages "2353-2362" .
<#_P77967-citation-10871367> a rdf:Statement ;
  rdf:subject <P77967> ;
  rdf:predicate up:citation ;
  rdf:object citation:10871367 ;
  a up:Citation_Statement ;
  up:scope "EXPRESSION IN E.COLI" ,
    "COFACTOR" .
citation:12878596 a up:Journal_Citation ;
  up:title "Purification and characterization of three members of the photolyase/cryptochrome family blue-light photoreceptors from Vibrio cholerae." ;
  up:author "Worthington E.N." ,
    "Kavakli I.H." ,
    "Berrocal-Tito G." ,
    "Bondo B.E." ,
    "Sancar A." ;
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  foaf:primaryTopicOf <https://pubmed.ncbi.nlm.nih.gov/12878596> ;
  dcterms:identifier "doi:10.1074/jbc.m305792200" ;
  up:date "2003"^^xsd:gYear ;
  up:name "J. Biol. Chem." ;
  up:volume "278" ;
  up:pages "39143-39154" .
<#_P77967-citation-12878596> a rdf:Statement ;
  rdf:subject <P77967> ;
  rdf:predicate up:citation ;
  rdf:object citation:12878596 ;
  a up:Citation_Statement ;
  up:scope "DISCUSSION OF SEQUENCE AND COFACTOR" .
citation:12535521 a up:Journal_Citation ;
  up:title "Identification of a new cryptochrome class. Structure, function, and evolution." ;
  up:author "Brudler R." ,
    "Hitomi K." ,
    "Daiyasu H." ,
    "Toh H." ,
    "Kucho K." ,
    "Ishiura M." ,
    "Kanehisa M." ,
    "Roberts V.A." ,
    "Todo T." ,
    "Tainer J.A." ,
    "Getzoff E.D." ;
  skos:exactMatch pubmed:12535521 ;
  foaf:primaryTopicOf <https://pubmed.ncbi.nlm.nih.gov/12535521> ;
  dcterms:identifier "doi:10.1016/s1097-2765(03)00008-x" ;
  up:date "2003"^^xsd:gYear ;
  up:name "Mol. Cell" ;
  up:volume "11" ;
  up:pages "59-67" .
<#_P77967-citation-12535521> a rdf:Statement ;
  rdf:subject <P77967> ;
  rdf:predicate up:citation ;
  rdf:object citation:12535521 ;
  a up:Citation_Statement ;
  up:scope "X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 2-453" ,
    "CHARACTERIZATION" .
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  up:sequenceDiscrepancy <P77967#EMBL_BAA17766.1> .
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<P77967#EMBL_BAA17766.1> rdfs:comment "Different initiation." .
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  up:database database:PIR .
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  up:database database:PDB ;
  up:method up:X-Ray_Crystallography ;
  up:resolution "1.90"^^xsd:decimal ;
  up:chainSequenceMapping <http://purl.uniprot.org/isoforms/P77967-1#PDB_1NP7_tt38tt489> .
<http://purl.uniprot.org/isoforms/P77967-1#PDB_1NP7_tt38tt489> up:chain "A/B=38-489" .
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  up:database database:AlphaFoldDB .
<http://purl.uniprot.org/smr/P77967> a up:Resource ;
  up:database database:SMR .
<http://purl.uniprot.org/intact/P77967> a up:Resource ;
  up:database database:IntAct ;
  rdfs:comment "3" .
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  up:database database:STRING .
<http://purl.uniprot.org/drugbank/DB03147> a up:Resource ;
  up:database database:DrugBank ;
  rdfs:comment "Flavin adenine dinucleotide" .
<http://purl.uniprot.org/paxdb/1148-gene:10498633> a up:Resource ;
  up:database database:PaxDb .
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  up:database database:EnsemblBacteria ;
  up:translatedTo <http://rdf.ebi.ac.uk/resource/ensembl.protein/BAA17766> ;
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  up:database database:KEGG .
<http://purl.uniprot.org/eggnog/COG0415> a up:Resource ;
  up:database database:eggNOG ;
  rdfs:comment "Bacteria" .
<http://purl.uniprot.org/inparanoid/P77967> a up:Resource ;
  up:database database:InParanoid .
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  up:database database:PhylomeDB .
<http://purl.uniprot.org/evolutionarytrace/P77967> a up:Resource ;
  up:database database:EvolutionaryTrace .
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  up:database database:InterPro ;
  rdfs:comment "Crypto/Photolyase_FAD-like_sf" .
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  up:database database:InterPro ;
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  up:database database:InterPro ;
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  up:database database:InterPro ;
  rdfs:comment "DNA_photolyase_1_CS_C" .
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  up:database database:InterPro ;
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  rdfs:comment "CRYPTOCHROME DASH" ;
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  rdfs:comment "Cryptochrome/photolyase FAD-binding domain" ;
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  rdfs:comment "Cryptochrome/photolyase, N-terminal domain" ;
  up:signatureSequenceMatch <http://purl.uniprot.org/isoforms/P77967-1#SUPFAM_SSF52425_match_1> .
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  rdfs:comment "PHR_CRY_ALPHA_BETA" ;
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<P77967#SIP17BD6C6F80D60C3A> a up:Structured_Name ;
  up:fullName "Cryptochrome DASH" .
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  skos:prefLabel "cry" ;
  skos:altLabel "phr" ,
    "phrB" ;
  up:locusName "sll1629" .
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  rdfs:comment "May have a photoreceptor function. Binds DNA; represses transcription of at least 8 genes, including slr0364 and slr1866. Does not encode a DNA photolyase function. Its disruption does not affect circadian rhythm." .
<P77967#SIP2EE7D6D8F2CF7765> a up:Cofactor_Annotation ;
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  up:cofactor <http://purl.obolibrary.org/obo/CHEBI_57692> .
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  up:attribution <P77967#attribution-981121153D1D34A98FDE19C8DE7F2D7B> .
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<P77967#SIP010B50A3D5708EA0> a up:Cofactor_Annotation ;
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annotation:PRO_0000235311 a up:Chain_Annotation ;
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position:22578708459435822tt1 a faldo:Position ,
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  up:mass 57040 ;
  up:md5Checksum "685af81d665ec1c60613c3bc34e95945" ;
  rdf:value "MKHVPPTVLVWFRNDLRLHDHEPLHRALKSGLAITAVYCYDPRQFAQTHQGFAKTGPWRSNFLQQSVQNLAESLQKVGNKLLVTTGLPEQVIPQIAKQINAKTIYYHREVTQEELDVERNLVKQLTILGIEAKGYWGSTLCHPEDLPFSIQDLPDLFTKFRKDIEKKKISIRPCFFAPSQLLPSPNIKLELTAPPPEFFPQINFDHRSVLAFQGGETAGLARLQDYFWHGDRLKDYKETRNGMVGADYSSKFSPWLALGCLSPRFIYQEVKRYEQERVSNDSTHWLIFELLWRDFFRFVAQKYGNKLFNRGGLLNKNFPWQEDQVRFELWRSGQTGYPLVDANMRELNLTGFMSNRGRQNVASFLCKNLGIDWRWGAEWFESCLIDYDVCSNWGNWNYTAGIGNDARDFRYFNIPKQSQQYDPQGTYLRHWLPELKNLPGDKIHQPWLLSATEQKQWGVQLGVDYPRPCVNFHQSVEARRKIEQMGVIA" .
<P77967#attribution-BCD67FFDCAB6DDEA2C9B27B77B8BED1D> dcterms:creator <http://purl.uniprot.org/goa-projects/InterPro> ;
  up:evidence ECO:0007669 .
<P77967#attribution-96CE74A9F3F0C8BB5F9634363907F7B8> up:manual true ;
  up:evidence ECO:0000250 ;
  up:source <Q84KJ5> .
<P77967#attribution-981121153D1D34A98FDE19C8DE7F2D7B> up:manual true ;
  up:evidence ECO:0000269 ;
  up:source citation:10871367 .
<P77967#attribution-1F1D235CEE6E9F517881B603655DF439> up:manual true ;
  up:evidence ECO:0000305 .
<P77967#attribution-DF144D79C317271EAD02DDC0FC437F90> up:evidence ECO:0007829 ;
  up:source <http://rdf.wwpdb.org/pdb/1NP7> .