ID   YDIS_ECOLI              Reviewed;         429 AA.
AC   P77337;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   04-NOV-2026, entry version 156.
DE   RecName: Full=Probable electron transfer flavoprotein-quinone oxidoreductase YdiS;
DE            EC=1.5.5.-;
GN   Name=ydiS; OrderedLocusNames=b1699, JW1689;
OS   Escherichia coli (strain K12).
OC   Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
OC   Enterobacterales; Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=9097039; DOI=10.1093/dnares/3.6.363;
RA   Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T.,
RA   Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K.,
RA   Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S.,
RA   Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G.,
RA   Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y.,
RA   Wada C., Yamamoto Y., Horiuchi T.;
RT   "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT   the 28.0-40.1 min region on the linkage map.";
RL   DNA Res. 3:363-377(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- FUNCTION: Probably accepts electrons from YdiQ/YdiR and reduces a
CC       quinone.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000305};
CC   -!- SIMILARITY: Belongs to the ETF-QO/FixC family. {ECO:0000305}.
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DR   EMBL; U00096; AAC74769.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA15468.1; -; Genomic_DNA.
DR   PIR; C64928; C64928.
DR   RefSeq; NP_416214.1; NC_000913.3.
DR   RefSeq; WP_001278525.1; NZ_CP009789.1.
DR   AlphaFoldDB; P77337; -.
DR   SMR; P77337; -.
DR   BioGRID; 4260294; 238.
DR   FunCoup; P77337; 763.
DR   IntAct; P77337; 5.
DR   STRING; 511145.b1699; -.
DR   jPOST; P77337; -.
DR   PaxDb; 511145-b1699; -.
DR   EnsemblBacteria; AAC74769; AAC74769; b1699.
DR   GeneID; 946212; -.
DR   KEGG; ecj:JW1689; -.
DR   KEGG; eco:b1699; -.
DR   KEGG; ecoc:C3026_09730; -.
DR   PATRIC; fig|1411691.4.peg.558; -.
DR   EchoBASE; EB3735; -.
DR   eggNOG; COG0644; Bacteria.
DR   HOGENOM; CLU_050977_0_0_6; -.
DR   InParanoid; P77337; -.
DR   OMA; ACIMYGG; -.
DR   OrthoDB; 103324at2; -.
DR   PhylomeDB; P77337; -.
DR   BioCyc; EcoCyc:G6922-MONOMER; -.
DR   PRO; PR:P77337; -.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR002938; FAD-bd.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR039651; FixC-like.
DR   InterPro; IPR059103; FixC-like_C.
DR   NCBIfam; NF007542; fixC; 1.
DR   NCBIfam; NF007450; PRK10015.1; 1.
DR   PANTHER; PTHR43624; ELECTRON TRANSFER FLAVOPROTEIN-QUINONE OXIDOREDUCTASE YDIS-RELATED; 1.
DR   PANTHER; PTHR43624:SF2; ELECTRON TRANSFER FLAVOPROTEIN-QUINONE OXIDOREDUCTASE YDIS-RELATED; 1.
DR   Pfam; PF26311; ETF-QO_FixC_C; 1.
DR   Pfam; PF01494; FAD_binding_3; 1.
DR   PRINTS; PR00420; RNGMNOXGNASE.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Reference proteome.
FT   CHAIN           1..429
FT                   /note="Probable electron transfer flavoprotein-quinone
FT                   oxidoreductase YdiS"
FT                   /id="PRO_0000200696"
FT   BINDING         8..22
FT                   /ligand="FAD"
FT                   /ligand_id="ChEBI:CHEBI:57692"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   429 AA;  45923 MW;  860789D79EDA6FA2 CRC64;
     MSDDKFDAIV VGAGVAGSVA ALVMARAGLD VLVIERGDSA GCKNMTGGRL YAHTLEAIIP
     GFAVSAPVER KVTREKISFL TEESAVTLDF HREQPDVPQH ASYTVLRNRL DPWLMEQAEQ
     AGAQFIPGVR VDALVREGNK VTGVQAGDDI LEANVVILAD GVNSMLGRSL GMVPASDPHH
     YAVGVKEVIG LTPEQINDRF NITGEEGAAW LFAGSPSDGL MGGGFLYTNK DSISLGLVCG
     LGDIAHAQKS VPQMLEDFKQ HPAIRPLISG GKLLEYSAHM VPEGGLAMVP QLVNEGVMIV
     GDAAGFCLNL GFTVRGMDLA IASAQAAATT VIAAKERADF SASSLAQYKR ELEQSCVMRD
     MQHFRKIPAL MENPRLFSQY PRMVADIMNE MFTIDGKPNQ PVRKMIMGHA KKIGLINLLK
     DGIKGATAL
//