ID   RSXG_ECOLI              Reviewed;         206 AA.
AC   P77285;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   02-SEP-2026, entry version 174.
DE   RecName: Full=Ion-translocating oxidoreductase complex subunit G {ECO:0000255|HAMAP-Rule:MF_00479, ECO:0000305};
DE            EC=7.-.-.- {ECO:0000255|HAMAP-Rule:MF_00479, ECO:0000305};
DE   AltName: Full=Rsx electron transport complex subunit G {ECO:0000255|HAMAP-Rule:MF_00479, ECO:0000305};
GN   Name=rsxG {ECO:0000255|HAMAP-Rule:MF_00479,
GN   ECO:0000303|PubMed:12773378}; Synonyms=rnfG, ydgP;
GN   OrderedLocusNames=b1631, JW1623;
OS   Escherichia coli (strain K12).
OC   Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
OC   Enterobacterales; Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=9097039; DOI=10.1093/dnares/3.6.363;
RA   Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T.,
RA   Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K.,
RA   Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S.,
RA   Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G.,
RA   Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y.,
RA   Wada C., Yamamoto Y., Horiuchi T.;
RT   "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT   the 28.0-40.1 min region on the linkage map.";
RL   DNA Res. 3:363-377(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [4]
RP   FUNCTION, SUBUNIT, AND GENE NAME.
RX   PubMed=12773378; DOI=10.1093/emboj/cdg252;
RA   Koo M.S., Lee J.H., Rah S.Y., Yeo W.S., Lee J.W., Lee K.L., Koh Y.S.,
RA   Kang S.O., Roe J.H.;
RT   "A reducing system of the superoxide sensor SoxR in Escherichia coli.";
RL   EMBO J. 22:2614-2622(2003).
CC   -!- FUNCTION: Part of a membrane-bound complex that couples electron
CC       transfer with translocation of ions across the membrane (By
CC       similarity). Required to maintain the reduced state of SoxR. Probably
CC       transfers electron from NAD(P)H to SoxR (PubMed:12773378).
CC       {ECO:0000255|HAMAP-Rule:MF_00479, ECO:0000269|PubMed:12773378}.
CC   -!- COFACTOR:
CC       Name=FMN; Xref=ChEBI:CHEBI:58210; Evidence={ECO:0000255|HAMAP-
CC         Rule:MF_00479};
CC   -!- SUBUNIT: The complex is composed of six subunits: RsxA, RsxB, RsxC,
CC       RsxD, RsxE and RsxG. {ECO:0000255|HAMAP-Rule:MF_00479,
CC       ECO:0000305|PubMed:12773378}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_00479, ECO:0000305}; Single-pass membrane protein
CC       {ECO:0000255|HAMAP-Rule:MF_00479}.
CC   -!- SIMILARITY: Belongs to the RnfG family. {ECO:0000255|HAMAP-
CC       Rule:MF_00479}.
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DR   EMBL; U00096; AAC74703.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA15385.1; -; Genomic_DNA.
DR   PIR; A64920; A64920.
DR   RefSeq; NP_416148.1; NC_000913.3.
DR   RefSeq; WP_000920784.1; NZ_CP009789.1.
DR   AlphaFoldDB; P77285; -.
DR   SMR; P77285; -.
DR   BioGRID; 4261975; 111.
DR   BioGRID; 850518; 2.
DR   DIP; DIP-11722N; -.
DR   FunCoup; P77285; 94.
DR   IntAct; P77285; 1.
DR   STRING; 511145.b1631; -.
DR   TCDB; 3.D.6.1.4; the ion (h(+) or na(+))-translocating nadh:ferredoxin oxidoreductase (nfo or rnf) family.
DR   jPOST; P77285; -.
DR   PaxDb; 511145-b1631; -.
DR   EnsemblBacteria; AAC74703; AAC74703; b1631.
DR   GeneID; 75204476; -.
DR   GeneID; 946158; -.
DR   KEGG; ecj:JW1623; -.
DR   KEGG; eco:b1631; -.
DR   KEGG; ecoc:C3026_09370; -.
DR   PATRIC; fig|1411691.4.peg.630; -.
DR   EchoBASE; EB3696; -.
DR   eggNOG; COG4659; Bacteria.
DR   HOGENOM; CLU_077882_1_0_6; -.
DR   InParanoid; P77285; -.
DR   OMA; YSGAIHL; -.
DR   OrthoDB; 9784165at2; -.
DR   PhylomeDB; P77285; -.
DR   BioCyc; EcoCyc:G6875-MONOMER; -.
DR   PRO; PR:P77285; -.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IDA:EcoCyc.
DR   GO; GO:1990204; C:oxidoreductase complex; IDA:EcoCyc.
DR   GO; GO:0005886; C:plasma membrane; HDA:EcoCyc.
DR   GO; GO:0098797; C:plasma membrane protein complex; IDA:EcoCyc.
DR   GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   GO; GO:0022900; P:electron transport chain; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00479; RsxG_RnfG; 1.
DR   InterPro; IPR007329; FMN-bd.
DR   InterPro; IPR010209; Ion_transpt_RnfG/RsxG.
DR   InterPro; IPR063127; RnfG_N.
DR   NCBIfam; NF002519; PRK01908.1; 1.
DR   NCBIfam; TIGR01947; rnfG; 1.
DR   PANTHER; PTHR36118; ION-TRANSLOCATING OXIDOREDUCTASE COMPLEX SUBUNIT G; 1.
DR   PANTHER; PTHR36118:SF1; ION-TRANSLOCATING OXIDOREDUCTASE COMPLEX SUBUNIT G; 1.
DR   Pfam; PF04205; FMN_bind; 1.
DR   Pfam; PF29280; RnfG_N; 1.
DR   PIRSF; PIRSF006091; E_trnsport_RnfG; 1.
DR   SMART; SM00900; FMN_bind; 1.
PE   1: Evidence at protein level;
KW   Cell inner membrane; Cell membrane; Electron transport; Flavoprotein; FMN;
KW   Membrane; Phosphoprotein; Reference proteome; Translocase; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..206
FT                   /note="Ion-translocating oxidoreductase complex subunit G"
FT                   /id="PRO_0000214633"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00479"
FT   MOD_RES         174
FT                   /note="FMN phosphoryl threonine"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00479"
SQ   SEQUENCE   206 AA;  21912 MW;  68D0644418823956 CRC64;
     MLKTIRKHGI TLALFAAGST GLTAAINQMT KTTIAEQASL QQKALFDQVL PAERYNNALA
     QSCYLVTAPE LGKGEHRVYI AKQDDKPVAA VLEATAPDGY SGAIQLLVGA DFNGTVLGTR
     VTEHHETPGL GDKIELRLSD WITHFAGKKI SGADDAHWAV KKDGGDFDQF TGATITPRAV
     VNAVKRAGLY AQTLPAQLSQ LPACGE
//