ID YDJJ_ECOLI Reviewed; 347 AA. AC P77280; P78174; DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot. DT 01-FEB-1997, sequence version 1. DT 10-JUN-2026, entry version 159. DE RecName: Full=Uncharacterized zinc-type alcohol dehydrogenase-like protein YdjJ; DE EC=1.-.-.-; GN Name=ydjJ; OrderedLocusNames=b1774, JW1763; OS Escherichia coli (strain K12). OC Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; OC Enterobacterales; Enterobacteriaceae; Escherichia. OX NCBI_TaxID=83333; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911; RX PubMed=9097039; DOI=10.1093/dnares/3.6.363; RA Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T., RA Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K., RA Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S., RA Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., RA Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y., RA Wada C., Yamamoto Y., Horiuchi T.; RT "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to RT the 28.0-40.1 min region on the linkage map."; RL DNA Res. 3:363-377(1996). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=K12 / MG1655 / ATCC 47076; RX PubMed=9278503; DOI=10.1126/science.277.5331.1453; RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., RA Shao Y.; RT "The complete genome sequence of Escherichia coli K-12."; RL Science 277:1453-1462(1997). RN [3] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911; RX PubMed=16738553; DOI=10.1038/msb4100049; RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.; RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 RT and W3110."; RL Mol. Syst. Biol. 2:E1-E5(2006). CC -!- COFACTOR: CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250}; CC Note=Binds 2 Zn(2+) ions per subunit. {ECO:0000250}; CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase CC family. {ECO:0000305}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; U00096; AAC74844.1; -; Genomic_DNA. DR EMBL; AP009048; BAA15572.1; -; Genomic_DNA. DR PIR; F64937; F64937. DR RefSeq; NP_416288.1; NC_000913.3. DR RefSeq; WP_000798110.1; NZ_CP009789.1. DR PDB; 5VM2; X-ray; 1.98 A; A/B=1-347. DR AlphaFoldDB; P77280; -. DR SMR; P77280; -. DR BioGRID; 4260306; 432. DR FunCoup; P77280; 550. DR IntAct; P77280; 9. DR STRING; 511145.b1774; -. DR jPOST; P77280; -. DR PaxDb; 511145-b1774; -. DR EnsemblBacteria; AAC74844; AAC74844; b1774. DR GeneID; 946292; -. DR KEGG; ecj:JW1763; -. DR KEGG; eco:b1774; -. DR KEGG; ecoc:C3026_10125; -. DR PATRIC; fig|1411691.4.peg.480; -. DR EchoBASE; EB3259; -. DR eggNOG; COG1063; Bacteria. DR HOGENOM; CLU_026673_11_5_6; -. DR InParanoid; P77280; -. DR OMA; MRVAMYY; -. DR OrthoDB; 9773078at2; -. DR PhylomeDB; P77280; -. DR BioCyc; EcoCyc:G6961-MONOMER; -. DR PRO; PR:P77280; -. DR Proteomes; UP000000625; Chromosome. DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro. DR CDD; cd05285; sorbitol_DH; 1. DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1. DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1. DR InterPro; IPR013149; ADH-like_C. DR InterPro; IPR013154; ADH-like_N. DR InterPro; IPR002328; ADH_Zn_CS. DR InterPro; IPR020843; ER. DR InterPro; IPR011032; GroES-like_sf. DR InterPro; IPR036291; NAD(P)-bd_dom_sf. DR InterPro; IPR045306; SDH-like. DR PANTHER; PTHR43161; SORBITOL DEHYDROGENASE; 1. DR PANTHER; PTHR43161:SF9; SORBITOL DEHYDROGENASE; 1. DR Pfam; PF08240; ADH_N; 1. DR Pfam; PF00107; ADH_zinc_N; 1. DR SMART; SM00829; PKS_ER; 1. DR SUPFAM; SSF50129; GroES-like; 1. DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1. DR PROSITE; PS00059; ADH_ZINC; 1. DR PDBsum; 5VM2; -. PE 1: Evidence at protein level; KW 3D-structure; Metal-binding; Oxidoreductase; Reference proteome; Zinc. FT CHAIN 1..347 FT /note="Uncharacterized zinc-type alcohol dehydrogenase-like FT protein YdjJ" FT /id="PRO_0000160892" FT BINDING 39 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="1" FT /ligand_note="catalytic" FT /evidence="ECO:0000250" FT BINDING 65 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="1" FT /ligand_note="catalytic" FT /evidence="ECO:0000250" FT BINDING 95 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="2" FT /evidence="ECO:0000250" FT BINDING 98 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="2" FT /evidence="ECO:0000250" FT BINDING 101 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="2" FT /evidence="ECO:0000250" FT BINDING 109 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="2" FT /evidence="ECO:0000250" FT BINDING 152 FT /ligand="Zn(2+)" FT /ligand_id="ChEBI:CHEBI:29105" FT /ligand_label="1" FT /ligand_note="catalytic" FT /evidence="ECO:0000250" FT STRAND 3..10 FT /evidence="ECO:0007829|PDB:5VM2" FT STRAND 13..19 FT /evidence="ECO:0007829|PDB:5VM2" FT HELIX 20..25 FT /evidence="ECO:0007829|PDB:5VM2" FT STRAND 28..38 FT /evidence="ECO:0007829|PDB:5VM2" FT HELIX 40..48 FT /evidence="ECO:0007829|PDB:5VM2" FT STRAND 67..74 FT /evidence="ECO:0007829|PDB:5VM2" FT STRAND 86..89 FT /evidence="ECO:0007829|PDB:5VM2" FT STRAND 91..93 FT /evidence="ECO:0007829|PDB:5VM2" FT STRAND 96..98 FT /evidence="ECO:0007829|PDB:5VM2" FT HELIX 99..102 FT /evidence="ECO:0007829|PDB:5VM2" FT HELIX 106..108 FT /evidence="ECO:0007829|PDB:5VM2" FT TURN 118..120 FT /evidence="ECO:0007829|PDB:5VM2" FT STRAND 126..132 FT /evidence="ECO:0007829|PDB:5VM2" FT HELIX 133..135 FT /evidence="ECO:0007829|PDB:5VM2" FT STRAND 136..138 FT /evidence="ECO:0007829|PDB:5VM2" FT HELIX 145..163 FT /evidence="ECO:0007829|PDB:5VM2" FT STRAND 171..175 FT /evidence="ECO:0007829|PDB:5VM2" FT HELIX 179..190 FT /evidence="ECO:0007829|PDB:5VM2" FT STRAND 195..201 FT /evidence="ECO:0007829|PDB:5VM2" FT HELIX 203..211 FT /evidence="ECO:0007829|PDB:5VM2" FT STRAND 215..219 FT /evidence="ECO:0007829|PDB:5VM2" FT TURN 220..222 FT /evidence="ECO:0007829|PDB:5VM2" FT HELIX 225..232 FT /evidence="ECO:0007829|PDB:5VM2" FT TURN 233..235 FT /evidence="ECO:0007829|PDB:5VM2" FT STRAND 238..243 FT /evidence="ECO:0007829|PDB:5VM2" FT HELIX 248..253 FT /evidence="ECO:0007829|PDB:5VM2" FT HELIX 254..256 FT /evidence="ECO:0007829|PDB:5VM2" FT STRAND 258..268 FT /evidence="ECO:0007829|PDB:5VM2" FT HELIX 278..281 FT /evidence="ECO:0007829|PDB:5VM2" FT TURN 282..284 FT /evidence="ECO:0007829|PDB:5VM2" FT STRAND 286..290 FT /evidence="ECO:0007829|PDB:5VM2" FT HELIX 297..305 FT /evidence="ECO:0007829|PDB:5VM2" FT HELIX 312..314 FT /evidence="ECO:0007829|PDB:5VM2" FT STRAND 315..320 FT /evidence="ECO:0007829|PDB:5VM2" FT HELIX 321..323 FT /evidence="ECO:0007829|PDB:5VM2" FT HELIX 324..333 FT /evidence="ECO:0007829|PDB:5VM2" FT HELIX 335..337 FT /evidence="ECO:0007829|PDB:5VM2" FT STRAND 339..344 FT /evidence="ECO:0007829|PDB:5VM2" SQ SEQUENCE 347 AA; 37701 MW; F8E2172184626A3B CRC64; MKNSKAILQV PGTMKIISAE IPVPKEDEVL IKVEYVGICG SDVHGFESGP FIPPKDPNQE IGLGHECAGT VVAVGSRVRK FKPGDRVNIE PGVPCGHCRY CLEGKYNICP DVDFMATQPN YRGALTHYLC HPESFTYKLP DNMDTMEGAL VEPAAVGMHA AMLADVKPGK KIIILGAGCI GLMTLQACKC LGATEIAVVD VLEKRLAMAE QLGATVVING AKEDTIARCQ QFTEDMGADI VFETAGSAVT VKQAPYLVMR GGKIMIVGTV PGDSAINFLK INREVTIQTV FRYANRYPVT IEAISSGRFD VKSMVTHIYD YRDVQQAFEE SVNNKRDIIK GVIKISD //