ID   P74046_SYNY3            Unreviewed;       389 AA.
AC   P74046;
DT   01-FEB-1997, integrated into UniProtKB/TrEMBL.
DT   01-FEB-1997, sequence version 1.
DT   04-NOV-2026, entry version 129.
DE   SubName: Full=Ceramide glucosyltransferase {ECO:0000313|EMBL:BAA18121.1};
GN   OrderedLocusNames=slr0813 {ECO:0000313|EMBL:BAA18121.1};
OS   Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa).
OC   Bacteria; Bacillati; Cyanobacteriota; Cyanophyceae; Synechococcales;
OC   Merismopediaceae; Synechocystis.
OX   NCBI_TaxID=1111708 {ECO:0000313|EMBL:BAA18121.1, ECO:0000313|Proteomes:UP000001425};
RN   [1] {ECO:0000313|EMBL:BAA18121.1, ECO:0000313|Proteomes:UP000001425}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27184 / PCC 6803 / Kazusa
RC   {ECO:0000313|Proteomes:UP000001425};
RX   PubMed=8590279; DOI=10.1093/dnares/2.4.153;
RA   Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N.,
RA   Sugiura M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region
RT   from map positions 64% to 92% of the genome.";
RL   DNA Res. 2:153-166(1995).
RN   [2] {ECO:0000313|EMBL:BAA18121.1, ECO:0000313|Proteomes:UP000001425}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27184 / PCC 6803 / Kazusa
RC   {ECO:0000313|Proteomes:UP000001425};
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
CC   -!- PATHWAY: Lipid metabolism; sphingolipid metabolism.
CC       {ECO:0000256|ARBA:ARBA00004760}.
CC   -!- PATHWAY: Sphingolipid metabolism. {ECO:0000256|ARBA:ARBA00004991}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; BA000022; BAA18121.1; -; Genomic_DNA.
DR   PIR; S75560; S75560.
DR   AlphaFoldDB; P74046; -.
DR   SMR; P74046; -.
DR   STRING; 1148.gene:10498992; -.
DR   PaxDb; 1148-gene:10498992; -.
DR   EnsemblBacteria; BAA18121; BAA18121; BAA18121.
DR   KEGG; syn:slr0813; -.
DR   eggNOG; COG1215; Bacteria.
DR   InParanoid; P74046; -.
DR   OMA; AACVYAW; -.
DR   PhylomeDB; P74046; -.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0008120; F:ceramide glucosyltransferase activity; IBA:GO_Central.
DR   GO; GO:0006679; P:glucosylceramide biosynthetic process; IBA:GO_Central.
DR   CDD; cd02520; Glucosylceramide_synthase; 1.
DR   Gene3D; 3.90.550.10; Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A; 1.
DR   InterPro; IPR025993; Ceramide_glucosylTrfase.
DR   InterPro; IPR017835; Hopen-assoc_HpnI.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   NCBIfam; TIGR03472; HpnI; 1.
DR   PANTHER; PTHR12726; CERAMIDE GLUCOSYLTRANSFERASE; 1.
DR   PANTHER; PTHR12726:SF0; CERAMIDE GLUCOSYLTRANSFERASE; 1.
DR   Pfam; PF13506; Glyco_transf_21; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE   4: Predicted;
KW   Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001425};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        284..303
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        309..329
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   389 AA;  43587 MW;  2F565578B2A60C5B CRC64;
     MNLGQWGEIM SWLCLLPISG GIVYNLLTVF TTSLFLARSL PKQDFQPGVS VLKPVRGLEK
     NLEANLRTIA QQNYPAYEVI YCVQDPQDPA LPIVKKLQAE FGPEKIIVAV HQIEQGANGK
     VNNLLGGLKH AKYDILVISD SDTNLRPDYL ATMVSPLGDR LVGCVTTPFK LTQAQTWYEG
     LELLSINADF MPSVLFAEVT GASKACLGPS IAIRRSTLTE IGGLESLADY LVEDFELGQR
     VWTGGLKMVL LPYVIDAGVN LDNWTNWWSH QLYWDQNTYL ARPLPFLATI IIRAVPFAFL
     FTFCHWSEPW AWLILFITLA TRYGTAAIVA QELKDGETIR YLPLLLLRDC FGLVFWALSF
     SQRQVLWRGI TYRLTKGGKM IPASPIPKS
//