ID PSAC_ARATH Reviewed; 81 AA. AC P62090; P07136; P25252; Q9MRU0; Q9T2J4; DT 01-APR-1988, integrated into UniProtKB/Swiss-Prot. DT 23-JAN-2007, sequence version 2. DT 02-SEP-2026, entry version 125. DE RecName: Full=Photosystem I iron-sulfur center {ECO:0000255|HAMAP-Rule:MF_01303}; DE EC=1.97.1.12 {ECO:0000255|HAMAP-Rule:MF_01303}; DE AltName: Full=9 kDa polypeptide {ECO:0000255|HAMAP-Rule:MF_01303}; DE AltName: Full=PSI-C {ECO:0000255|HAMAP-Rule:MF_01303}; DE AltName: Full=Photosystem I subunit VII {ECO:0000255|HAMAP-Rule:MF_01303}; DE AltName: Full=PsaC {ECO:0000255|HAMAP-Rule:MF_01303}; GN Name=psaC {ECO:0000255|HAMAP-Rule:MF_01303}; Synonyms=frxA; GN OrderedLocusNames=AtCg01060; OS Arabidopsis thaliana (Mouse-ear cress). OG Plastid; Chloroplast. OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis. OX NCBI_TaxID=3702; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Columbia; RX PubMed=10574454; DOI=10.1093/dnares/6.5.283; RA Sato S., Nakamura Y., Kaneko T., Asamizu E., Tabata S.; RT "Complete structure of the chloroplast genome of Arabidopsis thaliana."; RL DNA Res. 6:283-290(1999). RN [2] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 68-81. RC TISSUE=Leaf; RX PubMed=11181728; DOI=10.1093/jxb/52.354.179; RA Lopez-Serrano M., del Campo E.M., Sabater B., Martin M.; RT "Primary transcripts of ndhD of Liliaceae and Aloaceae require editing of RT the start and 20th codons."; RL J. Exp. Bot. 52:179-180(2001). CC -!- FUNCTION: Apoprotein for the two 4Fe-4S centers FA and FB of CC photosystem I (PSI); essential for photochemical activity. FB is the CC terminal electron acceptor of PSI, donating electrons to ferredoxin. CC The C-terminus interacts with PsaA/B/D and helps assemble the protein CC into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI CC is a plastocyanin-ferredoxin oxidoreductase, converting photonic CC excitation into a charge separation, which transfers an electron from CC the donor P700 chlorophyll pair to the spectroscopically characterized CC acceptors A0, A1, FX, FA and FB in turn. {ECO:0000255|HAMAP- CC Rule:MF_01303}. CC -!- CATALYTIC ACTIVITY: CC Reaction=reduced [plastocyanin] + hnu + oxidized [2Fe-2S]-[ferredoxin] CC = oxidized [plastocyanin] + reduced [2Fe-2S]-[ferredoxin]; CC Xref=Rhea:RHEA:30407, Rhea:RHEA-COMP:10000, Rhea:RHEA-COMP:10001, CC Rhea:RHEA-COMP:10039, Rhea:RHEA-COMP:10040, ChEBI:CHEBI:29036, CC ChEBI:CHEBI:30212, ChEBI:CHEBI:33737, ChEBI:CHEBI:33738, CC ChEBI:CHEBI:49552; EC=1.97.1.12; Evidence={ECO:0000255|HAMAP- CC Rule:MF_01303}; CC -!- COFACTOR: CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883; CC Evidence={ECO:0000255|HAMAP-Rule:MF_01303}; CC Note=Binds 2 [4Fe-4S] clusters. Cluster 2 is most probably the CC spectroscopically characterized electron acceptor FA and cluster 1 is CC most probably FB. {ECO:0000255|HAMAP-Rule:MF_01303}; CC -!- SUBUNIT: The eukaryotic PSI reaction center is composed of at least 11 CC subunits. {ECO:0000255|HAMAP-Rule:MF_01303}. CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane CC {ECO:0000255|HAMAP-Rule:MF_01303}; Peripheral membrane protein CC {ECO:0000255|HAMAP-Rule:MF_01303}; Stromal side {ECO:0000255|HAMAP- CC Rule:MF_01303}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AP000423; BAA84438.1; -; Genomic_DNA. DR EMBL; AJ278354; CAB96190.1; -; Genomic_DNA. DR RefSeq; NP_051110.1; NC_000932.1. DR PDB; 7WFD; EM; 3.25 A; AC=1-81. DR PDB; 7WFE; EM; 3.25 A; BC=1-81. DR PDB; 7WG5; EM; 3.89 A; AC/BC=1-81. DR PDB; 8J6Z; EM; 2.79 A; C=1-81. DR PDB; 8J7A; EM; 3.06 A; C=1-81. DR PDB; 8J7B; EM; 3.22 A; C=1-81. DR PDB; 9GBI; EM; 3.13 A; C=1-81. DR PDB; 9GC2; EM; 3.29 A; C=1-81. DR AlphaFoldDB; P62090; -. DR EMDB; EMD-32462; -. DR EMDB; EMD-32463; -. DR EMDB; EMD-32477; -. DR EMDB; EMD-36021; -. DR EMDB; EMD-36036; -. DR EMDB; EMD-36037; -. DR EMDB; EMD-51219; -. DR EMDB; EMD-51227; -. DR SMR; P62090; -. DR BioGRID; 29954; 2. DR FunCoup; P62090; 225. DR STRING; 3702.P62090; -. DR TCDB; 5.B.4.1.1; the plant photosystem i supercomplex (psi) family. DR iPTMnet; P62090; -. DR PaxDb; 3702-P62090; -. DR ProteomicsDB; 226347; -. DR GeneID; 844750; -. DR KEGG; ath:ArthCp075; -. DR Araport; ATCG01060; -. DR TAIR; ATCG01060; PSAC. DR eggNOG; ENOG502S26M; Eukaryota. DR HOGENOM; CLU_139698_8_0_1; -. DR InParanoid; P62090; -. DR OMA; GHMSHAV; -. DR BioCyc; MetaCyc:MONOMER-1097; -. DR PRO; PR:P62090; -. DR Proteomes; UP000006548; Chloroplast. DR ExpressionAtlas; P62090; baseline and differential. DR GO; GO:0009507; C:chloroplast; HDA:TAIR. DR GO; GO:0009533; C:chloroplast stromal thylakoid; TAS:TAIR. DR GO; GO:0009534; C:chloroplast thylakoid; HDA:TAIR. DR GO; GO:0009535; C:chloroplast thylakoid membrane; HDA:TAIR. DR GO; GO:0005634; C:nucleus; ISM:TAIR. DR GO; GO:0009522; C:photosystem I; TAS:TAIR. DR GO; GO:0009536; C:plastid; HDA:TAIR. DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro. DR GO; GO:0009055; F:electron transfer activity; IEA:UniProtKB-UniRule. DR GO; GO:0003729; F:mRNA binding; IDA:TAIR. DR GO; GO:0015979; P:photosynthesis; IEP:TAIR. DR GO; GO:0009773; P:photosynthetic electron transport in photosystem I; IEA:InterPro. DR FunFam; 3.30.70.20:FF:000001; Photosystem I iron-sulfur center; 1. DR Gene3D; 3.30.70.20; -; 1. DR HAMAP; MF_01303; PSI_PsaC; 1. DR InterPro; IPR017896; 4Fe4S_Fe-S-bd. DR InterPro; IPR017900; 4Fe4S_Fe_S_CS. DR InterPro; IPR050157; PSI_iron-sulfur_center. DR InterPro; IPR017491; PSI_PsaC. DR NCBIfam; TIGR03048; PS_I_psaC; 1. DR PANTHER; PTHR24960:SF79; PHOTOSYSTEM I IRON-SULFUR CENTER; 1. DR PANTHER; PTHR24960; PHOTOSYSTEM I IRON-SULFUR CENTER-RELATED; 1. DR Pfam; PF14697; Fer4_21; 1. DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1. DR PROSITE; PS00198; 4FE4S_FER_1; 2. DR PROSITE; PS51379; 4FE4S_FER_2; 2. DR PDBsum; 7WFD; -. DR PDBsum; 7WFE; -. DR PDBsum; 7WG5; -. DR PDBsum; 8J6Z; -. DR PDBsum; 8J7A; -. DR PDBsum; 8J7B; -. DR PDBsum; 9GBI; -. DR PDBsum; 9GC2; -. PE 1: Evidence at protein level; KW 3D-structure; 4Fe-4S; Chloroplast; Electron transport; Iron; Iron-sulfur; KW Membrane; Metal-binding; Oxidoreductase; Photosynthesis; Photosystem I; KW Plastid; Reference proteome; Repeat; Thylakoid; Transport. FT CHAIN 1..81 FT /note="Photosystem I iron-sulfur center" FT /id="PRO_0000061970" FT DOMAIN 2..31 FT /note="4Fe-4S ferredoxin-type 1" FT /evidence="ECO:0000255|HAMAP-Rule:MF_01303" FT DOMAIN 39..68 FT /note="4Fe-4S ferredoxin-type 2" FT /evidence="ECO:0000255|HAMAP-Rule:MF_01303" FT BINDING 11 FT /ligand="[4Fe-4S] cluster" FT /ligand_id="ChEBI:CHEBI:49883" FT /ligand_label="1" FT /evidence="ECO:0000255|HAMAP-Rule:MF_01303" FT BINDING 14 FT /ligand="[4Fe-4S] cluster" FT /ligand_id="ChEBI:CHEBI:49883" FT /ligand_label="1" FT /evidence="ECO:0000255|HAMAP-Rule:MF_01303" FT BINDING 17 FT /ligand="[4Fe-4S] cluster" FT /ligand_id="ChEBI:CHEBI:49883" FT /ligand_label="1" FT /evidence="ECO:0000255|HAMAP-Rule:MF_01303" FT BINDING 21 FT /ligand="[4Fe-4S] cluster" FT /ligand_id="ChEBI:CHEBI:49883" FT /ligand_label="2" FT /evidence="ECO:0000255|HAMAP-Rule:MF_01303" FT BINDING 48 FT /ligand="[4Fe-4S] cluster" FT /ligand_id="ChEBI:CHEBI:49883" FT /ligand_label="2" FT /evidence="ECO:0000255|HAMAP-Rule:MF_01303" FT BINDING 51 FT /ligand="[4Fe-4S] cluster" FT /ligand_id="ChEBI:CHEBI:49883" FT /ligand_label="2" FT /evidence="ECO:0000255|HAMAP-Rule:MF_01303" FT BINDING 54 FT /ligand="[4Fe-4S] cluster" FT /ligand_id="ChEBI:CHEBI:49883" FT /ligand_label="2" FT /evidence="ECO:0000255|HAMAP-Rule:MF_01303" FT BINDING 58 FT /ligand="[4Fe-4S] cluster" FT /ligand_id="ChEBI:CHEBI:49883" FT /ligand_label="1" FT /evidence="ECO:0000255|HAMAP-Rule:MF_01303" FT STRAND 4..8 FT /evidence="ECO:0007829|PDB:8J6Z" FT HELIX 16..20 FT /evidence="ECO:0007829|PDB:8J6Z" FT STRAND 22..24 FT /evidence="ECO:0007829|PDB:8J6Z" FT STRAND 27..30 FT /evidence="ECO:0007829|PDB:8J6Z" FT STRAND 32..34 FT /evidence="ECO:0007829|PDB:8J6Z" FT STRAND 38..41 FT /evidence="ECO:0007829|PDB:8J6Z" FT HELIX 45..47 FT /evidence="ECO:0007829|PDB:8J6Z" FT HELIX 53..57 FT /evidence="ECO:0007829|PDB:8J6Z" FT STRAND 60..62 FT /evidence="ECO:0007829|PDB:8J6Z" FT STRAND 64..68 FT /evidence="ECO:0007829|PDB:8J6Z" FT TURN 74..78 FT /evidence="ECO:0007829|PDB:8J6Z" SQ SEQUENCE 81 AA; 9038 MW; 68071DB57FC603BF CRC64; MSHSVKIYDT CIGCTQCVRA CPTDVLEMIP WDGCKAKQIA SAPRTEDCVG CKRCESACPT DFLSVRVYLW HETTRSMGLA Y //