ID   RS7_DANRE               Reviewed;         194 AA.
AC   P62084;
DT   21-JUN-2004, integrated into UniProtKB/Swiss-Prot.
DT   21-JUN-2004, sequence version 1.
DT   02-SEP-2026, entry version 117.
DE   RecName: Full=Small ribosomal subunit protein eS7 {ECO:0000305};
DE   AltName: Full=40S ribosomal protein S7;
GN   Name=rps7; ORFNames=zgc:73216;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=15138505; DOI=10.1371/journal.pbio.0020139;
RA   Amsterdam A., Sadler K.C., Lai K., Farrington S., Bronson R.T., Lees J.A.,
RA   Hopkins N.;
RT   "Many ribosomal protein genes are cancer genes in zebrafish.";
RL   PLoS Biol. 2:690-698(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen;
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA   Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA   Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA   White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA   Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA   Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA   Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA   Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA   Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA   Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA   Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA   McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA   Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA   Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA   Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA   Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA   Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA   Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA   Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA   Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA   Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA   Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA   de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA   Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the human
RT   genome.";
RL   Nature 496:498-503(2013).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Retina;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the small ribosomal subunit. The ribosome is a
CC       large ribonucleoprotein complex responsible for the synthesis of
CC       proteins in the cell. Required for rRNA maturation.
CC       {ECO:0000250|UniProtKB:P62081}.
CC   -!- SUBUNIT: Component of the small ribosomal subunit.
CC       {ECO:0000250|UniProtKB:P62081}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC       center, centrosome {ECO:0000250|UniProtKB:P62081}. Cytoplasm
CC       {ECO:0000250|UniProtKB:P62081}. Nucleus {ECO:0000250|UniProtKB:P62081}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS7 family.
CC       {ECO:0000305}.
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DR   EMBL; AY561508; AAS66961.1; -; mRNA.
DR   EMBL; BX276180; CAH68965.1; -; Genomic_DNA.
DR   EMBL; BC059562; AAH59562.1; -; mRNA.
DR   RefSeq; NP_957046.1; NM_200752.1.
DR   PDB; 7OYA; EM; 3.20 A; H2=1-194.
DR   PDB; 7OYB; EM; 2.40 A; H2=1-194.
DR   AlphaFoldDB; P62084; -.
DR   EMDB; EMD-13111; -.
DR   EMDB; EMD-13112; -.
DR   SMR; P62084; -.
DR   FunCoup; P62084; 2481.
DR   STRING; 7955.ENSDARP00000109497; -.
DR   GlyGen; P62084; 1 site, 1 O-linked glycan (1 site).
DR   PaxDb; 7955-ENSDARP00000109497; -.
DR   PeptideAtlas; P62084; -.
DR   Ensembl; ENSDART00000126229; ENSDARP00000109497; ENSDARG00000042566.
DR   Ensembl; ENSDART00000190737; ENSDARP00000150273; ENSDARG00000042566.
DR   GeneID; 393725; -.
DR   KEGG; dre:393725; -.
DR   AGR; ZFIN:ZDB-GENE-040426-1718; -.
DR   CTD; 6201; -.
DR   ZFIN; ZDB-GENE-040426-1718; rps7.
DR   eggNOG; KOG3320; Eukaryota.
DR   GeneTree; ENSGT00390000014122; -.
DR   HOGENOM; CLU_088621_1_2_1; -.
DR   InParanoid; P62084; -.
DR   OMA; AAYHKVQ; -.
DR   OrthoDB; 1724687at2759; -.
DR   PhylomeDB; P62084; -.
DR   Reactome; R-DRE-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-DRE-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-DRE-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR   Reactome; R-DRE-72649; Translation initiation complex formation.
DR   Reactome; R-DRE-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-DRE-72695; Formation of the ternary complex, and subsequently, the 43S complex.
DR   Reactome; R-DRE-72702; Ribosomal scanning and start codon recognition.
DR   Reactome; R-DRE-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-DRE-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   Reactome; R-DRE-9954714; PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA.
DR   Reactome; R-DRE-9954716; ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA.
DR   PRO; PR:P62084; -.
DR   Proteomes; UP000000437; Chromosome 20.
DR   Bgee; ENSDARG00000042566; Expressed in tail bud paraxial mesoderm and 27 other cell types or tissues.
DR   GO; GO:0005813; C:centrosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0022627; C:cytosolic small ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0032040; C:small-subunit processome; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0043009; P:chordate embryonic development; IMP:ZFIN.
DR   GO; GO:0030097; P:hemopoiesis; IMP:ZFIN.
DR   GO; GO:0051726; P:regulation of cell cycle; IMP:ZFIN.
DR   GO; GO:0042274; P:ribosomal small subunit biogenesis; IBA:GO_Central.
DR   GO; GO:0006364; P:rRNA processing; IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   InterPro; IPR000554; Ribosomal_eS7.
DR   InterPro; IPR047861; Ribosomal_eS7_CS.
DR   PANTHER; PTHR11278; 40S RIBOSOMAL PROTEIN S7; 1.
DR   PANTHER; PTHR11278:SF0; SMALL RIBOSOMAL SUBUNIT PROTEIN ES7; 1.
DR   Pfam; PF01251; Ribosomal_S7e; 1.
DR   PROSITE; PS00948; RIBOSOMAL_S7E; 1.
DR   PDBsum; 7OYA; -.
DR   PDBsum; 7OYB; -.
PE   1: Evidence at protein level;
KW   3D-structure; Cytoplasm; Cytoskeleton; Nucleus; Reference proteome;
KW   Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..194
FT                   /note="Small ribosomal subunit protein eS7"
FT                   /id="PRO_0000174193"
FT   STRAND          11..14
FT                   /evidence="ECO:0007829|PDB:7OYB"
FT   HELIX           18..32
FT                   /evidence="ECO:0007829|PDB:7OYB"
FT   STRAND          33..35
FT                   /evidence="ECO:0007829|PDB:7OYB"
FT   HELIX           37..41
FT                   /evidence="ECO:0007829|PDB:7OYB"
FT   STRAND          47..53
FT                   /evidence="ECO:0007829|PDB:7OYB"
FT   TURN            54..56
FT                   /evidence="ECO:0007829|PDB:7OYB"
FT   STRAND          57..64
FT                   /evidence="ECO:0007829|PDB:7OYB"
FT   HELIX           69..84
FT                   /evidence="ECO:0007829|PDB:7OYB"
FT   TURN            85..87
FT                   /evidence="ECO:0007829|PDB:7OYB"
FT   STRAND          88..96
FT                   /evidence="ECO:0007829|PDB:7OYB"
FT   HELIX           101..103
FT                   /evidence="ECO:0007829|PDB:7OYB"
FT   STRAND          106..108
FT                   /evidence="ECO:0007829|PDB:7OYB"
FT   HELIX           118..120
FT                   /evidence="ECO:0007829|PDB:7OYB"
FT   HELIX           122..132
FT                   /evidence="ECO:0007829|PDB:7OYB"
FT   TURN            133..136
FT                   /evidence="ECO:0007829|PDB:7OYB"
FT   STRAND          141..146
FT                   /evidence="ECO:0007829|PDB:7OYB"
FT   STRAND          148..150
FT                   /evidence="ECO:0007829|PDB:7OYB"
FT   STRAND          152..157
FT                   /evidence="ECO:0007829|PDB:7OYB"
FT   HELIX           163..165
FT                   /evidence="ECO:0007829|PDB:7OYB"
FT   TURN            166..168
FT                   /evidence="ECO:0007829|PDB:7OYB"
FT   HELIX           170..180
FT                   /evidence="ECO:0007829|PDB:7OYB"
FT   STRAND          185..188
FT                   /evidence="ECO:0007829|PDB:7OYB"
SQ   SEQUENCE   194 AA;  22250 MW;  5010023055B0BAD8 CRC64;
     MFSTSAKIVK PNGEKPDEFE SGISQALLEL EMNSDLKAQL RELHITAAKE IEVGGSRKAI
     IIFVPVPQLK SFQKIQVRLV RELEKKFSGK HVVFIAQRRI LPKPTRKSRT KNKQKRPRSR
     TLTNVHDAIL EDLVFPSEIV GKRIRVKLDS SRLIKVHLDK AQQNNVEHKV ETFAGVYKKL
     TGKDVIFEFP EFQL
//