ID   CU067_HUMAN             Reviewed;         204 AA.
AC   P58512; P58556; Q495D3; Q495D5;
DT   23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2002, sequence version 1.
DT   02-SEP-2026, entry version 112.
DE   RecName: Full=Uncharacterized protein encoded by LINC01547 {ECO:0000312|HGNC:HGNC:15707};
GN   Name=LINC01547 {ECO:0000312|HGNC:HGNC:15707};
GN   Synonyms=C21orf67 {ECO:0000312|HGNC:HGNC:15707}, C21orf69
GN   {ECO:0000312|HGNC:HGNC:15707};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), AND NUCLEOTIDE SEQUENCE
RP   [MRNA] OF 152-204 (ISOFORM 3).
RX   PubMed=11707072; DOI=10.1006/geno.2001.6640;
RA   Reymond A., Friedli M., Neergaard Henrichsen C., Chapot F., Deutsch S.,
RA   Ucla C., Rossier C., Lyle R., Guipponi M., Antonarakis S.E.;
RT   "From PREDs and open reading frames to cDNA isolation: revisiting the human
RT   chromosome 21 transcription map.";
RL   Genomics 78:46-54(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=10830953; DOI=10.1038/35012518;
RA   Hattori M., Fujiyama A., Taylor T.D., Watanabe H., Yada T., Park H.-S.,
RA   Toyoda A., Ishii K., Totoki Y., Choi D.-K., Groner Y., Soeda E., Ohki M.,
RA   Takagi T., Sakaki Y., Taudien S., Blechschmidt K., Polley A., Menzel U.,
RA   Delabar J., Kumpf K., Lehmann R., Patterson D., Reichwald K., Rump A.,
RA   Schillhabel M., Schudy A., Zimmermann W., Rosenthal A., Kudoh J.,
RA   Shibuya K., Kawasaki K., Asakawa S., Shintani A., Sasaki T., Nagamine K.,
RA   Mitsuyama S., Antonarakis S.E., Minoshima S., Shimizu N., Nordsiek G.,
RA   Hornischer K., Brandt P., Scharfe M., Schoen O., Desario A., Reichelt J.,
RA   Kauer G., Bloecker H., Ramser J., Beck A., Klages S., Hennig S.,
RA   Riesselmann L., Dagand E., Wehrmeyer S., Borzym K., Gardiner K.,
RA   Nizetic D., Francis F., Lehrach H., Reinhardt R., Yaspo M.-L.;
RT   "The DNA sequence of human chromosome 21.";
RL   Nature 405:311-319(2000).
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=3;
CC       Name=1; Synonyms=A;
CC         IsoId=P58512-1; Sequence=Displayed;
CC       Name=2; Synonyms=B;
CC         IsoId=P58512-2; Sequence=VSP_003829, VSP_003830;
CC       Name=3;
CC         IsoId=P58512-3; Sequence=VSP_039828, VSP_039829;
CC   -!- TISSUE SPECIFICITY: Not detected in any tissue tested.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAK60445.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305};
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DR   EMBL; AF380178; AAL34496.1; -; mRNA.
DR   EMBL; AY035381; AAK60445.1; ALT_SEQ; mRNA.
DR   EMBL; AY040088; AAK74136.1; -; mRNA.
DR   EMBL; AL844908; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; P58512; -.
DR   BioMuta; HGNC:15707; -.
DR   MassIVE; P58512; -.
DR   PeptideAtlas; P58512; -.
DR   AGR; HGNC:15707; -.
DR   GeneCards; LINC01547; -.
DR   HGNC; HGNC:15707; LINC01547.
DR   InParanoid; P58512; -.
DR   PAN-GO; P58512; 0 GO annotations based on evolutionary models.
DR   ChiTaRS; LINC01547; human.
DR   Pharos; P58512; Tdark.
DR   PRO; PR:P58512; -.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; P58512; protein.
DR   GO; GO:0005783; C:endoplasmic reticulum; HDA:UniProtKB.
PE   2: Evidence at transcript level;
KW   Alternative splicing; Reference proteome.
FT   CHAIN           1..204
FT                   /note="Uncharacterized protein encoded by LINC01547"
FT                   /id="PRO_0000079526"
FT   REGION          1..73
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        41..57
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        60..70
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VAR_SEQ         1..22
FT                   /note="MGWDCRRTTVENPSPIRNCVNQ -> MARNRLIAASTSRTRAILPPQPLEK
FT                   (in isoform 3)"
FT                   /evidence="ECO:0000303|PubMed:11707072"
FT                   /id="VSP_039828"
FT   VAR_SEQ         72..82
FT                   /note="LAADLAGDALP -> CTSGASAGQKL (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:11707072"
FT                   /id="VSP_003829"
FT   VAR_SEQ         83..204
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:11707072"
FT                   /id="VSP_003830"
FT   VAR_SEQ         165..204
FT                   /note="GGFPACLPAPKSSTDSASSCFKGGREFSDPLDIPGAGAMG -> GFPVSWRT
FT                   RMRAFHLSLPGGAQLLTYLVKVLKRRTWRRNVDNNPGCLCVPS (in isoform 3)"
FT                   /evidence="ECO:0000303|PubMed:11707072"
FT                   /id="VSP_039829"
FT   CONFLICT        158
FT                   /note="W -> R (in Ref. 1; AAK60445)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   204 AA;  21308 MW;  F955EC4E414F2340 CRC64;
     MGWDCRRTTV ENPSPIRNCV NQEWPEGSSP GLTEGNTGLV RDLRPAHQDR SGTREDPAGQ
     ETTAITNPSP SLAADLAGDA LPGCLGAAAH QGPLLDRSSE STLGPQALEL EHCHERGCCR
     GCASFSPFPA PRCPSERLGA HSSRWAIRGR SKINPPPWAP ACLPGGFPAC LPAPKSSTDS
     ASSCFKGGRE FSDPLDIPGA GAMG
//