ID RL6_BUCAI Reviewed; 178 AA. AC P57576; DT 01-DEC-2000, integrated into UniProtKB/Swiss-Prot. DT 01-DEC-2000, sequence version 1. DT 04-NOV-2026, entry version 117. DE RecName: Full=Large ribosomal subunit protein uL6 {ECO:0000255|HAMAP-Rule:MF_01365}; DE AltName: Full=50S ribosomal protein L6 {ECO:0000305}; GN Name=rplF {ECO:0000255|HAMAP-Rule:MF_01365}; OrderedLocusNames=BU509; OS Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon OS pisum symbiotic bacterium). OC Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; OC Enterobacterales; Erwiniaceae; Buchnera. OX NCBI_TaxID=107806; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=APS; RX PubMed=10993077; DOI=10.1038/35024074; RA Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.; RT "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera RT sp. APS."; RL Nature 407:81-86(2000). CC -!- FUNCTION: This protein binds to the 23S rRNA, and is important in its CC secondary structure. It is located near the subunit interface in the CC base of the L7/L12 stalk, and near the tRNA binding site of the CC peptidyltransferase center. {ECO:0000255|HAMAP-Rule:MF_01365}. CC -!- SUBUNIT: Part of the 50S ribosomal subunit. {ECO:0000255|HAMAP- CC Rule:MF_01365}. CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL6 family. CC {ECO:0000255|HAMAP-Rule:MF_01365}. CC -!- SEQUENCE CAUTION: CC Sequence=BAB13202.1; Type=Erroneous initiation; Evidence={ECO:0000305}; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BA000003; BAB13202.1; ALT_INIT; Genomic_DNA. DR RefSeq; WP_009874460.1; NC_002528.1. DR AlphaFoldDB; P57576; -. DR SMR; P57576; -. DR STRING; 563178.BUAP5A_502; -. DR EnsemblBacteria; BAB13202; BAB13202; BAB13202. DR KEGG; buc:BU509; -. DR PATRIC; fig|107806.10.peg.514; -. DR eggNOG; COG0097; Bacteria. DR HOGENOM; CLU_065464_1_2_6; -. DR OMA; AACLRKF; -. DR Proteomes; UP000001806; Chromosome. DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IEA:TreeGrafter. DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule. DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro. DR GO; GO:0002181; P:cytoplasmic translation; IEA:TreeGrafter. DR FunFam; 3.90.930.12:FF:000001; 50S ribosomal protein L6; 1. DR Gene3D; 3.90.930.12; Ribosomal protein L6, alpha-beta domain; 2. DR HAMAP; MF_01365_B; Ribosomal_uL6_B; 1. DR InterPro; IPR000702; Ribosomal_uL6-like. DR InterPro; IPR036789; Ribosomal_uL6-like_a/b-dom_sf. DR InterPro; IPR020040; Ribosomal_uL6_a/b-dom. DR InterPro; IPR019906; Ribosomal_uL6_bact. DR InterPro; IPR002358; Ribosomal_uL6_CS. DR NCBIfam; TIGR03654; L6_bact; 1. DR PANTHER; PTHR11655; 60S/50S RIBOSOMAL PROTEIN L6/L9; 1. DR PANTHER; PTHR11655:SF14; LARGE RIBOSOMAL SUBUNIT PROTEIN UL6M; 1. DR Pfam; PF00347; Ribosomal_L6; 2. DR PIRSF; PIRSF002162; Ribosomal_L6; 1. DR PRINTS; PR00059; RIBOSOMALL6. DR SUPFAM; SSF56053; Ribosomal protein L6; 2. DR PROSITE; PS00525; RIBOSOMAL_L6_1; 1. PE 3: Inferred from homology; KW Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding; KW rRNA-binding. FT CHAIN 1..178 FT /note="Large ribosomal subunit protein uL6" FT /id="PRO_0000131040" SQ SEQUENCE 178 AA; 19751 MW; 49463317224FB58C CRC64; MSRVAKCPIV IPSGVNVQLD LQDISIKGKY GHLSRTIHQS VKIEFLNNQI IFSPRLGFSN GWAQAGTSRA LVNSMIIGVS EKFSKKLQLS GVGYRVSITK DNIINMSLGY SHIITYHLPK GINAENLSPT EIIIQGIDKQ LVGQIAANLR SYRTPEPYKG KGIRYSNEVV RIKEAKKK //