ID   YBHD_ECOLI              Reviewed;         317 AA.
AC   P52696; P75761;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   27-APR-2001, sequence version 3.
DT   02-SEP-2026, entry version 156.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator YbhD;
GN   Name=ybhD; OrderedLocusNames=b0768, JW5896;
OS   Escherichia coli (strain K12).
OC   Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
OC   Enterobacterales; Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA   Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA   Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA   Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA   Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA   Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA   Horiuchi T.;
RT   "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT   the 12.7-28.0 min region on the linkage map.";
RL   DNA Res. 3:137-155(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 210-317.
RC   STRAIN=K12;
RA   Shanmugam K.T.;
RL   Submitted (MAY-1995) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   IDENTIFICATION.
RA   Robison K.;
RL   Unpublished observations (DEC-1995).
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAA35432.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; U00096; AAC73855.2; -; Genomic_DNA.
DR   EMBL; AP009048; BAA35432.1; ALT_INIT; Genomic_DNA.
DR   EMBL; U27192; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; H64812; H64812.
DR   RefSeq; NP_415289.4; NC_000913.3.
DR   RefSeq; WP_001350493.1; NZ_CP009789.1.
DR   AlphaFoldDB; P52696; -.
DR   SMR; P52696; -.
DR   BioGRID; 4261144; 82.
DR   FunCoup; P52696; 32.
DR   STRING; 511145.b0768; -.
DR   PaxDb; 511145-b0768; -.
DR   EnsemblBacteria; AAC73855; AAC73855; b0768.
DR   GeneID; 944869; -.
DR   KEGG; ecj:JW5896; -.
DR   KEGG; eco:b0768; -.
DR   KEGG; ecoc:C3026_03895; -.
DR   PATRIC; fig|1411691.4.peg.1510; -.
DR   EchoBASE; EB3019; -.
DR   eggNOG; COG0583; Bacteria.
DR   HOGENOM; CLU_039613_6_0_6; -.
DR   InParanoid; P52696; -.
DR   OMA; PWIAGCP; -.
DR   OrthoDB; 8437302at2; -.
DR   PhylomeDB; P52696; -.
DR   BioCyc; EcoCyc:G6398-MONOMER; -.
DR   PRO; PR:P52696; -.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IBA:GO_Central.
DR   CDD; cd08440; PBP2_LTTR_like_4; 1.
DR   FunFam; 1.10.10.10:FF:000001; LysR family transcriptional regulator; 1.
DR   Gene3D; 3.40.190.290; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR050950; HTH-type_LysR_regulators.
DR   InterPro; IPR000847; LysR_HTH_N.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30419; HTH-TYPE TRANSCRIPTIONAL REGULATOR YBHD; 1.
DR   PANTHER; PTHR30419:SF30; LYSR FAMILY TRANSCRIPTIONAL REGULATOR; 1.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..317
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   YbhD"
FT                   /id="PRO_0000105780"
FT   DOMAIN          1..60
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        20..40
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   317 AA;  36058 MW;  8B02C4808B4665D2 CRC64;
     MKHELSSMKA FVILAESSSF NNAAKLLNIT QPALTRRIKK MEEDLHVQLF ERTTRKVTLT
     KAGKRLLPEA RELIKKFDET LFNIRDMNAY HRGMVTLACI PTAVFYFLPL AIGKFNELYP
     NIKVRILEQG TNNCMESVLC NESDFGINMN NVTNSSIDFT PLVNEPFVLA CRRDHPLAKK
     QLVEWQELVG YKMIGVRSSS GNRLLIEQQL ADKPWKLDWF YEVRHLSTSL GLVEAGLGIS
     ALPGLAMPHA PYSSIIGIPL VEPVIRRTLG IIRRKDAVLS PAAERFFALL INLWTDDKDN
     LWTNIVERQR HALQEIG
//