ID RS3_MYCGE Reviewed; 268 AA. AC P47403; DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot. DT 23-JAN-2007, sequence version 2. DT 02-SEP-2026, entry version 143. DE RecName: Full=Small ribosomal subunit protein uS3 {ECO:0000255|HAMAP-Rule:MF_01309}; DE AltName: Full=30S ribosomal protein S3 {ECO:0000305}; GN Name=rpsC {ECO:0000255|HAMAP-Rule:MF_01309}; GN Synonyms=rps3 {ECO:0000255|HAMAP-Rule:MF_01309}; GN OrderedLocusNames=MG157; OS Mycoplasmoides genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / OS G37) (Mycoplasma genitalium). OC Bacteria; Bacillati; Mycoplasmatota; Mycoplasmoidales; Mycoplasmoidaceae; OC Mycoplasmoides. OX NCBI_TaxID=243273; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37; RX PubMed=7569993; DOI=10.1126/science.270.5235.397; RA Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A., RA Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M., RA Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L., RA Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M., RA Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S., RA Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.; RT "The minimal gene complement of Mycoplasma genitalium."; RL Science 270:397-403(1995). CC -!- FUNCTION: Binds the lower part of the 30S subunit head. Binds mRNA in CC the 70S ribosome, positioning it for translation. {ECO:0000255|HAMAP- CC Rule:MF_01309}. CC -!- SUBUNIT: Part of the 30S ribosomal subunit. Forms a tight complex with CC proteins S10 and S14. {ECO:0000255|HAMAP-Rule:MF_01309}. CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS3 family. CC {ECO:0000255|HAMAP-Rule:MF_01309}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; L43967; AAC71375.1; -; Genomic_DNA. DR PIR; D64217; D64217. DR RefSeq; WP_009885841.1; NC_000908.2. DR AlphaFoldDB; P47403; -. DR SMR; P47403; -. DR FunCoup; P47403; 212. DR STRING; 243273.MG_157; -. DR GeneID; 99646988; -. DR KEGG; mge:MG_157; -. DR eggNOG; COG0092; Bacteria. DR HOGENOM; CLU_058591_0_2_14; -. DR InParanoid; P47403; -. DR OrthoDB; 9806396at2; -. DR BioCyc; MGEN243273:G1GJ2-181-MONOMER; -. DR Proteomes; UP000000807; Chromosome. DR GO; GO:0022627; C:cytosolic small ribosomal subunit; IBA:GO_Central. DR GO; GO:0003729; F:mRNA binding; IEA:UniProtKB-UniRule. DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule. DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro. DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule. DR CDD; cd02412; KH-II_30S_S3; 1. DR FunFam; 3.30.300.20:FF:000001; 30S ribosomal protein S3; 1. DR Gene3D; 3.30.300.20; -; 1. DR Gene3D; 3.30.1140.32; Ribosomal protein S3, C-terminal domain; 1. DR HAMAP; MF_01309_B; Ribosomal_uS3_B; 1. DR InterPro; IPR004087; KH_dom. DR InterPro; IPR015946; KH_dom-like_a/b. DR InterPro; IPR004044; KH_dom_type_2. DR InterPro; IPR009019; KH_sf_prok-type. DR InterPro; IPR036419; Ribosomal_S3_C_sf. DR InterPro; IPR057258; Ribosomal_uS3. DR InterPro; IPR005704; Ribosomal_uS3_bact. DR InterPro; IPR001351; Ribosomal_uS3_C. DR InterPro; IPR018280; Ribosomal_uS3_CS. DR NCBIfam; TIGR01009; rpsC_bact; 1. DR PANTHER; PTHR11760; 30S/40S RIBOSOMAL PROTEIN S3; 1. DR PANTHER; PTHR11760:SF19; SMALL RIBOSOMAL SUBUNIT PROTEIN US3C; 1. DR Pfam; PF07650; KH_2; 1. DR Pfam; PF00189; Ribosomal_S3_C; 1. DR SMART; SM00322; KH; 1. DR SUPFAM; SSF54814; Prokaryotic type KH domain (KH-domain type II); 1. DR SUPFAM; SSF54821; Ribosomal protein S3 C-terminal domain; 1. DR PROSITE; PS50823; KH_TYPE_2; 1. DR PROSITE; PS00548; RIBOSOMAL_S3; 1. PE 3: Inferred from homology; KW Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding; KW rRNA-binding. FT INIT_MET 1 FT /note="Removed" FT /evidence="ECO:0000250" FT CHAIN 2..268 FT /note="Small ribosomal subunit protein uS3" FT /id="PRO_0000130150" FT DOMAIN 40..110 FT /note="KH type-2" FT /evidence="ECO:0000255|HAMAP-Rule:MF_01309" SQ SEQUENCE 268 AA; 29986 MW; 2BFE5D5D1923515E CRC64; MGQKVNSNGL RFGINKNWIS RWTASSNQQT ATWLVQDEKI RNLFFINYRN AQVSNVEIER TQTTVDVYVY AAQPALLIGS ENKNIQKITK MIQIIVGRKI KLDLTINEIG SPMLSSRIIA RDIANAIENR VPLRSAMRQA LTKVLKAGAN GIKVLVSGRL NGAEIARDKM YIEGNMPLST LRADIDYAFE KAKTTYGIIG VKVWINRGMI YAKGLNRTPA HILHPQKKQL KTPTIKKTNS VIAKQKLTGS DIETASLKAL TDNNQNHE //