ID   RPOE_MYCGE              Reviewed;         145 AA.
AC   P47268; Q49195;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   02-SEP-2026, entry version 122.
DE   RecName: Full=Probable DNA-directed RNA polymerase subunit delta;
DE   AltName: Full=RNAP delta factor;
GN   Name=rpoE; OrderedLocusNames=MG022;
OS   Mycoplasmoides genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 /
OS   G37) (Mycoplasma genitalium).
OC   Bacteria; Bacillati; Mycoplasmatota; Mycoplasmoidales; Mycoplasmoidaceae;
OC   Mycoplasmoides.
OX   NCBI_TaxID=243273;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA   Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA   Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA   Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA   Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA   Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA   Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT   "The minimal gene complement of Mycoplasma genitalium.";
RL   Science 270:397-403(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-95.
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=8253680; DOI=10.1128/jb.175.24.7918-7930.1993;
RA   Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III;
RT   "A survey of the Mycoplasma genitalium genome by using random sequencing.";
RL   J. Bacteriol. 175:7918-7930(1993).
CC   -!- FUNCTION: Participates in both the initiation and recycling phases of
CC       transcription. In the presence of the delta subunit, RNAP displays an
CC       increased specificity of transcription, a decreased affinity for
CC       nucleic acids, and an increased efficiency of RNA synthesis because of
CC       enhanced recycling (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: RNAP is composed of a core of 2 alpha, a beta and a beta'
CC       subunits. The core is associated with a delta subunit and one of
CC       several sigma factors (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RpoE family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAC43196.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; L43967; AAC71238.1; -; Genomic_DNA.
DR   EMBL; U01721; AAC43196.1; ALT_INIT; Unassigned_DNA.
DR   PIR; D64202; D64202.
DR   RefSeq; WP_009885918.1; NC_000908.2.
DR   AlphaFoldDB; P47268; -.
DR   SMR; P47268; -.
DR   FunCoup; P47268; 3.
DR   STRING; 243273.MG_022; -.
DR   GeneID; 99646830; -.
DR   KEGG; mge:MG_022; -.
DR   eggNOG; COG3343; Bacteria.
DR   HOGENOM; CLU_1775406_0_0_14; -.
DR   InParanoid; P47268; -.
DR   OrthoDB; 400111at2; -.
DR   BioCyc; MGEN243273:G1GJ2-22-MONOMER; -.
DR   Proteomes; UP000000807; Chromosome.
DR   GO; GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.1250; RNA polymerase, subunit delta, N-terminal domain; 1.
DR   HAMAP; MF_00357; RNApol_bact_RpoE; 1.
DR   InterPro; IPR007759; Asxl_HARE-HTH.
DR   InterPro; IPR038087; RNAP_delta_N_dom_sf.
DR   InterPro; IPR029757; RpoE.
DR   NCBIfam; TIGR04567; RNAP_delt_lowGC; 1.
DR   Pfam; PF05066; HARE-HTH; 1.
DR   PROSITE; PS51913; HTH_HARE; 1.
PE   3: Inferred from homology;
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Reference proteome;
KW   Transcription; Transferase.
FT   CHAIN           1..145
FT                   /note="Probable DNA-directed RNA polymerase subunit delta"
FT                   /id="PRO_0000204318"
FT   DOMAIN          6..75
FT                   /note="HTH HARE-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01261"
SQ   SEQUENCE   145 AA;  17057 MW;  C7A1901C94E2A41F CRC64;
     MQLEYLNLIS QAKVIAEKQF KANPFSFETI WKEVVKHFKI SKQDEPSLIG RFYQDFLEDP
     NFVYLGDRKW KLRDFMKFDE WNKISQSMFV TKEIFEEGYE DLSNKKVEPE EGVGDFIMGN
     DGDDNETGSE IVQGLINDSF SEENQ
//