ID   XYLH_HAEIN              Reviewed;         375 AA.
AC   P45045;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   10-JUN-2026, entry version 129.
DE   RecName: Full=Xylose transport system permease protein XylH;
GN   Name=xylH; OrderedLocusNames=HI_1109;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
OC   Pasteurellales; Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: Part of the binding protein-dependent transport system for D-
CC       xylose. Probably responsible for the translocation of the substrate
CC       across the membrane (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the binding protein-dependent transport system
CC       permease family. AraH/RbsC subfamily. {ECO:0000305}.
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DR   EMBL; L42023; AAC22763.1; -; Genomic_DNA.
DR   PIR; A64183; A64183.
DR   STRING; 71421.HI_1109; -.
DR   EnsemblBacteria; AAC22763; AAC22763; HI_1109.
DR   KEGG; hin:HI_1109; -.
DR   PATRIC; fig|71421.8.peg.1158; -.
DR   eggNOG; COG4214; Bacteria.
DR   HOGENOM; CLU_028880_2_0_6; -.
DR   OrthoDB; 5422926at2; -.
DR   PhylomeDB; P45045; -.
DR   BioCyc; HINF71421:G1GJ1-1144-MONOMER; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd06579; TM_PBP1_transp_AraH_like; 1.
DR   InterPro; IPR001851; ABC_transp_permease.
DR   PANTHER; PTHR32196; ABC TRANSPORTER PERMEASE PROTEIN YPHD-RELATED-RELATED; 1.
DR   PANTHER; PTHR32196:SF32; XYLOSE TRANSPORT SYSTEM PERMEASE PROTEIN XYLH; 1.
DR   Pfam; PF02653; BPD_transp_2; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Sugar transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..375
FT                   /note="Xylose transport system permease protein XylH"
FT                   /id="PRO_0000060237"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        52..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        85..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        118..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        159..179
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        199..219
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        220..240
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        271..291
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        319..339
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        348..368
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   375 AA;  39510 MW;  21E9D6D343CF062F CRC64;
     MFKLKSVNLQ VYIMLIAIAV IMAFFSVATD GAYLSARNIS NLLRQTSITG XLAIGMVFVI
     ISAEIDLSVG SLMGLLGGFA AIADVWWGFP LPVTIIATIA LGLIFGIWNG WWVAYRKVPS
     FIVTLAGYLA FRGILIGLTN GTTVSPISGT MTVIGQGYLS DIAGVILGGI AVIGFVLWGN
     YQRRSRQQLQ LEVSALSKDF TKYALFAVIV LGAIYLLNDY RGIPFPVLVL AVLAILGLFL
     SRKTSFGRHV YAIGGNIDAA KLSGINVEKT KLIIFAMNGV LVAIAGLILS ARLGAGSPSA
     GQNAELDAIA ACVIGGASLA GGVGSVFGVV IGALIIASLD NGMSMLDVPT FWQYIVKGGI
     LLLAVWIDTS NKKKM
//