ID   FDHE_HAEIN              Reviewed;         302 AA.
AC   P44452;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   04-NOV-2026, entry version 122.
DE   RecName: Full=Protein FdhE homolog;
GN   Name=fdhE; OrderedLocusNames=HI_0009;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
OC   Pasteurellales; Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: Necessary for formate dehydrogenase activity. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the FdhE family. {ECO:0000305}.
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DR   EMBL; L42023; AAC21687.1; -; Genomic_DNA.
DR   PIR; C64042; C64042.
DR   AlphaFoldDB; P44452; -.
DR   SMR; P44452; -.
DR   STRING; 71421.HI_0009; -.
DR   EnsemblBacteria; AAC21687; AAC21687; HI_0009.
DR   KEGG; hin:HI_0009; -.
DR   PATRIC; fig|71421.8.peg.9; -.
DR   eggNOG; COG3058; Bacteria.
DR   HOGENOM; CLU_055275_0_0_6; -.
DR   OMA; AAEWHMV; -.
DR   OrthoDB; 9794151at2; -.
DR   PhylomeDB; P44452; -.
DR   BioCyc; HINF71421:G1GJ1-9-MONOMER; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0008199; F:ferric iron binding; IBA:GO_Central.
DR   GO; GO:0051604; P:protein maturation; IBA:GO_Central.
DR   CDD; cd16341; FdhE; 1.
DR   FunFam; 3.90.1670.10:FF:000001; Protein FdhE; 1.
DR   Gene3D; 3.90.1670.10; FdhE-like domain; 1.
DR   HAMAP; MF_00611; FdeH; 1.
DR   InterPro; IPR024064; FdhE-like_sf.
DR   InterPro; IPR056796; FdhE_C.
DR   InterPro; IPR056797; FdhE_central.
DR   InterPro; IPR056774; FdhE_N.
DR   InterPro; IPR006452; Formate_DH_accessory.
DR   NCBIfam; TIGR01562; FdhE; 1.
DR   NCBIfam; NF002925; fdhE; 1.
DR   PANTHER; PTHR37689; PROTEIN FDHE; 1.
DR   PANTHER; PTHR37689:SF1; PROTEIN FDHE; 1.
DR   Pfam; PF24860; FdhE_C; 1.
DR   Pfam; PF24859; FdhE_central; 1.
DR   Pfam; PF04216; FdhE_N; 1.
DR   PIRSF; PIRSF018296; Format_dh_formtn; 1.
DR   SUPFAM; SSF144020; FdhE-like; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..302
FT                   /note="Protein FdhE homolog"
FT                   /id="PRO_0000189642"
SQ   SEQUENCE   302 AA;  34224 MW;  376F3A031710CBA7 CRC64;
     MSIKILSESE IKQVANSYQA PAVLFANPKN LYQRRAKRLR DLAQNHPLSD YLLFAADIVE
     SQLSTLEKNP LPPQQLEQLN TIEPLNAKTF KRNSIWREYL TEILDEIKPK ANEQIAATIE
     FLEKASSAEL EEMANKLLAQ EFNLVSSDKA VFIWAALSLY WLQAAQQIPH NSQVENAENL
     HHCPVCGSLP VASMVQIGTS QGLRYLHCNL CESEWNLVRA QCTNCNSHDK LEMWSLNEEL
     ALVRAETCGS CESYLKMMFQ EKDPYVEPVA DDLASIFLDI EMEEKGFARS GLNPFIFPAE
     EA
//