ID   YJK7_YEAST              Reviewed;         387 AA.
AC   P42947; D6VW77;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   04-NOV-2026, entry version 146.
DE   RecName: Full=Uncharacterized protein YJL107C;
GN   OrderedLocusNames=YJL107C; ORFNames=J0813;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 96604 / S288c / FY1679;
RX   PubMed=7483851; DOI=10.1002/yea.320110909;
RA   Rasmussen S.W.;
RT   "A 37.5 kb region of yeast chromosome X includes the SME1, MEF2, GSH1 and
RT   CSD3 genes, a TCP-1-related gene, an open reading frame similar to the
RT   DAL80 gene, and a tRNA(Arg).";
RL   Yeast 11:873-883(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=8641269; DOI=10.1002/j.1460-2075.1996.tb00557.x;
RA   Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C.,
RA   Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D.,
RA   Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J.,
RA   Heumann K., Hilger F., Hollenberg C.P., Huang M.-E., Jacq C.,
RA   Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E.,
RA   Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T.,
RA   Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B.,
RA   Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R.,
RA   Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N.,
RA   To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H.,
RA   von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.;
RT   "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.";
RL   EMBO J. 15:2031-2049(1996).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=17322287; DOI=10.1101/gr.6037607;
RA   Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA   Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA   Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA   Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA   LaBaer J.;
RT   "Approaching a complete repository of sequence-verified protein-encoding
RT   clones for Saccharomyces cerevisiae.";
RL   Genome Res. 17:536-543(2007).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 360-387, AND CONFIRMATION OF
RP   FRAMESHIFT.
RC   STRAIN=ATCC 204511 / S288c / AB972;
RX   PubMed=12844361; DOI=10.1186/gb-2003-4-7-r45;
RA   Brachat S., Dietrich F.S., Voegeli S., Zhang Z., Stuart L., Lerch A.,
RA   Gates K., Gaffney T.D., Philippsen P.;
RT   "Reinvestigation of the Saccharomyces cerevisiae genome annotation by
RT   comparison to the genome of a related fungus: Ashbya gossypii.";
RL   Genome Biol. 4:R45.1-R45.13(2003).
RN   [6]
RP   CONFIRMATION OF FRAMESHIFT.
RC   STRAIN=ATCC 204508 / S288c, and ATCC 28383 / FL100 / VTT C-80102;
RX   PubMed=11054818;
RX   DOI=10.1002/1097-0061(200011)16:15<1377::aid-yea637>3.0.co;2-0;
RA   Sychrova H., Braun V., Potier S., Souciet J.L.;
RT   "Organization of specific genomic regions of Zygosaccharomyces rouxii and
RT   Pichia sorbitophila: comparison with Saccharomyces cerevisiae.";
RL   Yeast 16:1377-1385(2000).
RN   [7]
RP   LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX   PubMed=14562106; DOI=10.1038/nature02046;
RA   Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA   O'Shea E.K., Weissman J.S.;
RT   "Global analysis of protein expression in yeast.";
RL   Nature 425:737-741(2003).
CC   -!- MISCELLANEOUS: Present with 1480 molecules/cell in log phase SD medium.
CC       {ECO:0000269|PubMed:14562106}.
CC   -!- SIMILARITY: Belongs to the ThrE exporter (TC 2.A.79) family.
CC       {ECO:0000305}.
CC   -!- CAUTION: This is a truncated version of a ThrE family protein. Strain
CC       S288c has a frameshift in position 382, which disrupts the gene coding
CC       for this protein and produces two ORFs YJL107C and YJL108C. A
CC       contiguous sequence for a S.cerevisiae ThrE family protein can be found
CC       in strain YJM789 (AC A6ZQL9). {ECO:0000305}.
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DR   EMBL; X85021; CAA59387.1; -; Genomic_DNA.
DR   EMBL; Z49383; CAA89403.1; -; Genomic_DNA.
DR   EMBL; AY557885; AAS56211.1; -; Genomic_DNA.
DR   EMBL; AY227895; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BK006943; DAA08693.1; -; Genomic_DNA.
DR   PIR; S53380; S53380.
DR   RefSeq; NP_012428.1; NM_001181540.1.
DR   BioGRID; 33649; 148.
DR   DIP; DIP-5095N; -.
DR   IntAct; P42947; 1.
DR   STRING; 4932.YJL107C; -.
DR   iPTMnet; P42947; -.
DR   PaxDb; 4932-YJL107C; -.
DR   PeptideAtlas; P42947; -.
DR   EnsemblFungi; YJL107C_mRNA; YJL107C; YJL107C.
DR   GeneID; 853337; -.
DR   KEGG; sce:YJL107C; -.
DR   VEuPathDB; FungiDB:YJL107C; -.
DR   AGR; SGD:S000003643; -.
DR   SGD; S000003643; YJL107C.
DR   eggNOG; ENOG502QPMM; Eukaryota.
DR   HOGENOM; CLU_060178_0_0_1; -.
DR   InParanoid; P42947; -.
DR   OMA; DSQGCNN; -.
DR   OrthoDB; 413008at2759; -.
DR   BioCyc; YEAST:G3O-31561-MONOMER; -.
DR   PRO; PR:P42947; -.
DR   InterPro; IPR010619; ThrE-like_N.
DR   InterPro; IPR051361; ThrE/Ser_Exporter.
DR   PANTHER; PTHR31082; PHEROMONE-REGULATED MEMBRANE PROTEIN 10; 1.
DR   PANTHER; PTHR31082:SF4; PHEROMONE-REGULATED MEMBRANE PROTEIN 10; 1.
DR   Pfam; PF06738; ThrE; 1.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Proteomes; UP000002311; Chromosome X.
DR   RNAct; P42947; protein.
DR   BioGRID-ORCS; 853337; 0 hits in 10 CRISPR screens.
DR   AlphaFoldDB; P42947; -.
DR   FunCoup; P42947; 63.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..387
FT                   /note="Uncharacterized protein YJL107C"
FT                   /id="PRO_0000203046"
FT   REGION          1..126
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          138..169
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          275..298
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        32..45
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        49..63
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        78..93
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        155..169
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        275..296
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   387 AA;  42508 MW;  D7659D1955F5677F CRC64;
     MDGRNEKPTT PVSDFRVGSS EQSQAGVNLE DSSDHRTSNS AESKKGNLSG KSISDLGISN
     NDNKNVRFTA DTDALENDLS SRSTETSDNS KGTDGQDEED RPARHKRKPK VSFTHLRNNG
     KDGDDETFIK KIINNLTGNQ GGLVPGLAPI PSENENGKND IEKNNRNEEI PLSDLADASK
     IVDVHEGDDK EKLEALKLEG DVNCTSDGET LGSSSKNSFL APAVDHFDDY AENNSSDDNE
     GFIETSTYVP PPSQVKSGVL GSLLKLYQNE DQNSSSIFSD SQAVTTDDEG ISSTAGNKDV
     PVAKRSRLQN LKGKAKKGRM PRLKKRLKTE AKITVHIADI LQRHRFILRM CRALMMYGAP
     THRLEEYMVM TSRVLEIDGQ FCIFQVV
//