ID   CAHC_HORVU              Reviewed;         324 AA.
AC   P40880;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   10-JUN-2026, entry version 105.
DE   RecName: Full=Carbonic anhydrase, chloroplastic;
DE            EC=4.2.1.1;
DE   AltName: Full=Carbonate dehydratase;
DE   Flags: Precursor;
OS   Hordeum vulgare (Barley).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum.
OX   NCBI_TaxID=4513;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=7784519; DOI=10.1104/pp.108.1.433;
RA   Bracey M.H., Bartlett S.G.;
RT   "Sequence of a cDNA encoding carbonic anhydrase from barley.";
RL   Plant Physiol. 108:433-434(1995).
CC   -!- FUNCTION: Reversible hydration of carbon dioxide.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=hydrogencarbonate + H(+) = CO2 + H2O; Xref=Rhea:RHEA:10748,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16526,
CC         ChEBI:CHEBI:17544; EC=4.2.1.1;
CC   -!- SUBUNIT: Homohexamer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast stroma {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the beta-class carbonic anhydrase family.
CC       {ECO:0000305}.
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DR   EMBL; L36959; AAC41656.1; -; mRNA.
DR   PIR; T04478; T04478.
DR   AlphaFoldDB; P40880; -.
DR   SMR; P40880; -.
DR   GO; GO:0009570; C:chloroplast stroma; IEA:UniProtKB-SubCell.
DR   GO; GO:0004089; F:carbonate dehydratase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0015976; P:carbon utilization; IEA:InterPro.
DR   CDD; cd00884; beta_CA_cladeB; 1.
DR   FunFam; 3.40.1050.10:FF:000008; Carbonic anhydrase; 1.
DR   Gene3D; 3.40.1050.10; Carbonic anhydrase; 1.
DR   InterPro; IPR045066; Beta_CA_cladeB.
DR   InterPro; IPR001765; Carbonic_anhydrase.
DR   InterPro; IPR015892; Carbonic_anhydrase_CS.
DR   InterPro; IPR036874; Carbonic_anhydrase_sf.
DR   PANTHER; PTHR11002:SF56; BETA CARBONIC ANHYDRASE 2, CHLOROPLASTIC; 1.
DR   PANTHER; PTHR11002; CARBONIC ANHYDRASE; 1.
DR   Pfam; PF00484; Pro_CA; 1.
DR   SMART; SM00947; Pro_CA; 1.
DR   SUPFAM; SSF53056; beta-carbonic anhydrase, cab; 1.
DR   PROSITE; PS00704; PROK_CO2_ANHYDRASE_1; 1.
DR   PROSITE; PS00705; PROK_CO2_ANHYDRASE_2; 1.
PE   2: Evidence at transcript level;
KW   Chloroplast; Lyase; Plastid; Transit peptide; Zinc.
FT   TRANSIT         1..?
FT                   /note="Chloroplast"
FT                   /evidence="ECO:0000255"
FT   CHAIN           ?..324
FT                   /note="Carbonic anhydrase, chloroplastic"
FT                   /id="PRO_0000004268"
SQ   SEQUENCE   324 AA;  35074 MW;  026F541956F06E75 CRC64;
     MSLQIGRTER ARSPVFVFAH KRQLLHGRCS TIDNANCSTC SMKINSTCTL TALPIAALPG
     PRTTSHYSTA AANWCYATVA PRARSSTIAA SLGTPAPSSS ASFRPKLIRT TPVQAAPVAP
     ALMDAAVERL KTGFEKFKTE VYDKKPDFFE PLKAGQAPKY MVFACADSRV CPSVTLGLEP
     GEAFTIRNIA NMVPAYCKNK YAGVGSAIEY AVCALKVEVI VVIGHSRCGG IKALLSLKDG
     ADDSFHFVED WVRIGFPAKK KVQTECASMP FDDQCTVLEK EAVNVSLQNL LTYPFVKEGV
     TNGTLKLVGG HYDFVSGKFE TWEQ
//