ID RS27A_YEAST Reviewed; 82 AA. AC P35997; D6VX42; DT 01-JUN-1994, integrated into UniProtKB/Swiss-Prot. DT 01-JUN-1994, sequence version 1. DT 02-SEP-2026, entry version 188. DE RecName: Full=Small ribosomal subunit protein eS27A {ECO:0000303|PubMed:24524803}; DE AltName: Full=40S ribosomal protein S27-A {ECO:0000303|PubMed:9559554}; DE AltName: Full=RP61; DE AltName: Full=YS20; GN Name=RPS27A {ECO:0000303|PubMed:9559554}; OrderedLocusNames=YKL156W; OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; OC Saccharomycetales; Saccharomycetaceae; Saccharomyces. OX NCBI_TaxID=559292; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RC STRAIN=ATCC 204508 / S288c; RX PubMed=8091859; DOI=10.1002/yea.320100005; RA Vandenbol M., Bolle P.-A., Dion C., Portetelle D., Hilger F.; RT "DNA sequencing of a 36.2 kb fragment located between the FAS1 and LAP loci RT of chromosome XI of Saccharomyces cerevisiae."; RL Yeast 10:S35-S40(1994). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 204508 / S288c; RX PubMed=8196765; DOI=10.1038/369371a0; RA Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V., RA Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P., RA Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L., RA Daignan-Fornier B., del Rey F., Dion C., Domdey H., Duesterhoeft A., RA Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H., RA Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L., RA Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M., RA Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H., RA Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J., RA Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H., RA Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J., RA Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S., RA Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F., RA Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R., RA Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W., RA Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M., RA Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C., RA Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H., RA Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L., RA van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S., RA von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M., RA Becker I., Mewes H.-W.; RT "Complete DNA sequence of yeast chromosome XI."; RL Nature 369:371-378(1994). RN [3] RP GENOME REANNOTATION. RC STRAIN=ATCC 204508 / S288c; RX PubMed=24374639; DOI=10.1534/g3.113.008995; RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.; RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now."; RL G3 (Bethesda) 4:389-398(2014). RN [4] RP NOMENCLATURE, AND SUBUNIT. RX PubMed=9559554; RX DOI=10.1002/(sici)1097-0061(19980330)14:5<471::aid-yea241>3.0.co;2-u; RA Planta R.J., Mager W.H.; RT "The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae."; RL Yeast 14:471-477(1998). RN [5] RP ANALYSIS OF N-TERMINUS. RX PubMed=10601260; DOI=10.1074/jbc.274.52.37035; RA Arnold R.J., Polevoda B., Reilly J.P., Sherman F.; RT "The action of N-terminal acetyltransferases on yeast ribosomal proteins."; RL J. Biol. Chem. 274:37035-37040(1999). RN [6] RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]. RX PubMed=14562095; DOI=10.1038/nature02026; RA Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., RA Weissman J.S., O'Shea E.K.; RT "Global analysis of protein localization in budding yeast."; RL Nature 425:686-691(2003). RN [7] RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS]. RX PubMed=14562106; DOI=10.1038/nature02046; RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., RA O'Shea E.K., Weissman J.S.; RT "Global analysis of protein expression in yeast."; RL Nature 425:737-741(2003). RN [8] RP METHYLATION AT CYS-40. RX PubMed=22650761; DOI=10.1021/bi300186g; RA Young B.D., Weiss D.I., Zurita-Lopez C.I., Webb K.J., Clarke S.G., RA McBride A.E.; RT "Identification of methylated proteins in the yeast small ribosomal RT subunit: a role for SPOUT methyltransferases in protein arginine RT methylation."; RL Biochemistry 51:5091-5104(2012). RN [9] RP NOMENCLATURE. RX PubMed=24524803; DOI=10.1016/j.sbi.2014.01.002; RA Ban N., Beckmann R., Cate J.H.D., Dinman J.D., Dragon F., Ellis S.R., RA Lafontaine D.L.J., Lindahl L., Liljas A., Lipton J.M., McAlear M.A., RA Moore P.B., Noller H.F., Ortega J., Panse V.G., Ramakrishnan V., RA Spahn C.M.T., Steitz T.A., Tchorzewski M., Tollervey D., Warren A.J., RA Williamson J.R., Wilson D., Yonath A., Yusupov M.; RT "A new system for naming ribosomal proteins."; RL Curr. Opin. Struct. Biol. 24:165-169(2014). RN [10] RP STRUCTURE BY ELECTRON MICROSCOPY. RX PubMed=20980660; DOI=10.1073/pnas.1009999107; RA Armache J.P., Jarasch A., Anger A.M., Villa E., Becker T., Bhushan S., RA Jossinet F., Habeck M., Dindar G., Franckenberg S., Marquez V., Mielke T., RA Thomm M., Berninghausen O., Beatrix B., Soding J., Westhof E., Wilson D.N., RA Beckmann R.; RT "Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome RT at 5.5-A resolution."; RL Proc. Natl. Acad. Sci. U.S.A. 107:19748-19753(2010). RN [11] RP X-RAY CRYSTALLOGRAPHY (3.00 ANGSTROMS) OF 80S RIBOSOME, SUBUNIT, AND RP SUBCELLULAR LOCATION. RX PubMed=22096102; DOI=10.1126/science.1212642; RA Ben-Shem A., Garreau de Loubresse N., Melnikov S., Jenner L., Yusupova G., RA Yusupov M.; RT "The structure of the eukaryotic ribosome at 3.0 A resolution."; RL Science 334:1524-1529(2011). RN [12] RP STRUCTURE BY ELECTRON MICROSCOPY (4.30 ANGSTROMS). RX PubMed=24200810; DOI=10.1126/science.1240585; RA Fernandez I.S., Bai X.C., Hussain T., Kelley A.C., Lorsch J.R., RA Ramakrishnan V., Scheres S.H.; RT "Molecular architecture of a eukaryotic translational initiation complex."; RL Science 342:1240585-1240585(2013). CC -!- FUNCTION: Component of the ribosome, a large ribonucleoprotein complex CC responsible for the synthesis of proteins in the cell. The small CC ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the CC encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) CC molecules. The large subunit (LSU) contains the ribosomal catalytic CC site termed the peptidyl transferase center (PTC), which catalyzes the CC formation of peptide bonds, thereby polymerizing the amino acids CC delivered by tRNAs into a polypeptide chain. The nascent polypeptides CC leave the ribosome through a tunnel in the LSU and interact with CC protein factors that function in enzymatic processing, targeting, and CC the membrane insertion of nascent chains at the exit of the ribosomal CC tunnel. {ECO:0000305|PubMed:22096102}. CC -!- COFACTOR: CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000305}; CC Note=Binds 1 zinc ion per subunit. {ECO:0000305}; CC -!- SUBUNIT: Component of the small ribosomal subunit (SSU). Mature yeast CC ribosomes consist of a small (40S) and a large (60S) subunit. The 40S CC small subunit contains 1 molecule of ribosomal RNA (18S rRNA) and 33 CC different proteins (encoded by 57 genes). The large 60S subunit CC contains 3 rRNA molecules (25S, 5.8S and 5S rRNA) and 46 different CC proteins (encoded by 81 genes) (PubMed:22096102, PubMed:9559554). CC {ECO:0000269|PubMed:22096102, ECO:0000305|PubMed:9559554}. CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:14562095, CC ECO:0000269|PubMed:22096102}. CC -!- PTM: The N-terminus is not modified. {ECO:0000269|PubMed:10601260}. CC -!- MISCELLANEOUS: Present with 43300 molecules/cell in log phase SD CC medium. {ECO:0000269|PubMed:14562106}. CC -!- MISCELLANEOUS: There are 2 genes for eS27 in yeast. {ECO:0000305}. CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS27 family. CC {ECO:0000305}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; Z26877; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; Z28156; CAA81998.1; -; Genomic_DNA. DR EMBL; Z28155; CAA81997.1; -; Genomic_DNA. DR EMBL; BK006944; DAA09008.1; -; Genomic_DNA. DR PIR; S37986; S37986. DR RefSeq; NP_012766.1; NM_001179722.1. DR PDB; 3J6X; EM; 6.10 A; 27=1-82. DR PDB; 3J6Y; EM; 6.10 A; 27=1-82. DR PDB; 3J77; EM; 6.20 A; 27=1-82. DR PDB; 3J78; EM; 6.30 A; 27=1-82. DR PDB; 4U3M; X-ray; 3.00 A; D7/d7=2-82. DR PDB; 4U3N; X-ray; 3.20 A; D7/d7=2-82. DR PDB; 4U3U; X-ray; 2.90 A; D7/d7=2-82. DR PDB; 4U4N; X-ray; 3.10 A; D7/d7=2-82. DR PDB; 4U4O; X-ray; 3.60 A; D7/d7=2-82. DR PDB; 4U4Q; X-ray; 3.00 A; D7/d7=2-82. DR PDB; 4U4R; X-ray; 2.80 A; D7/d7=2-82. DR PDB; 4U4U; X-ray; 3.00 A; D7/d7=2-82. DR PDB; 4U4Y; X-ray; 3.20 A; D7/d7=2-82. DR PDB; 4U4Z; X-ray; 3.10 A; D7/d7=2-82. DR PDB; 4U50; X-ray; 3.20 A; D7/d7=2-82. DR PDB; 4U51; X-ray; 3.20 A; D7/d7=2-82. DR PDB; 4U52; X-ray; 3.00 A; D7/d7=2-82. DR PDB; 4U53; X-ray; 3.30 A; D7/d7=2-82. DR PDB; 4U55; X-ray; 3.20 A; D7/d7=2-82. DR PDB; 4U56; X-ray; 3.45 A; D7/d7=2-82. DR PDB; 4U6F; X-ray; 3.10 A; D7/d7=2-82. DR PDB; 4V6I; EM; 8.80 A; AX=1-82. DR PDB; 4V88; X-ray; 3.00 A; Ab/Cb=1-82. DR PDB; 4V8Y; EM; 4.30 A; A1=1-82. DR PDB; 4V8Z; EM; 6.60 A; A1=1-82. DR PDB; 4V92; EM; 3.70 A; b=2-82. DR PDB; 5DAT; X-ray; 3.15 A; D7/d7=2-82. DR PDB; 5DC3; X-ray; 3.25 A; D7/d7=2-82. DR PDB; 5DGE; X-ray; 3.45 A; D7/d7=2-82. DR PDB; 5DGF; X-ray; 3.30 A; D7/d7=2-82. DR PDB; 5DGV; X-ray; 3.10 A; D7/d7=2-82. DR PDB; 5FCI; X-ray; 3.40 A; D7/d7=2-82. DR PDB; 5FCJ; X-ray; 3.10 A; D7/d7=2-82. DR PDB; 5I4L; X-ray; 3.10 A; D7/d7=2-82. DR PDB; 5JUO; EM; 4.00 A; YB=1-82. DR PDB; 5JUP; EM; 3.50 A; YB=1-82. DR PDB; 5JUS; EM; 4.20 A; YB=1-82. DR PDB; 5JUT; EM; 4.00 A; YB=1-82. DR PDB; 5JUU; EM; 4.00 A; YB=1-82. DR PDB; 5LL6; EM; 3.90 A; f=1-82. DR PDB; 5LYB; X-ray; 3.25 A; D7/d7=2-82. DR PDB; 5M1J; EM; 3.30 A; b2=2-82. DR PDB; 5MC6; EM; 3.80 A; f=1-82. DR PDB; 5MEI; X-ray; 3.50 A; c/d7=2-82. DR PDB; 5NDG; X-ray; 3.70 A; D7/d7=2-82. DR PDB; 5NDV; X-ray; 3.30 A; D7/d7=2-82. DR PDB; 5NDW; X-ray; 3.70 A; D7/d7=2-82. DR PDB; 5OBM; X-ray; 3.40 A; D7/d7=2-82. DR PDB; 5ON6; X-ray; 3.10 A; c/d7=2-82. DR PDB; 5TBW; X-ray; 3.00 A; c/d7=2-82. DR PDB; 5TGA; X-ray; 3.30 A; D7/d7=2-82. DR PDB; 5TGM; X-ray; 3.50 A; D7/d7=2-82. DR PDB; 5WYJ; EM; 8.70 A; Sc=1-82. DR PDB; 5WYK; EM; 4.50 A; Sc=1-82. DR PDB; 6EML; EM; 3.60 A; f=1-82. DR PDB; 6FAI; EM; 3.40 A; b=1-82. DR PDB; 6GQ1; EM; 4.40 A; AR=2-82. DR PDB; 6GQB; EM; 3.90 A; AR=2-82. DR PDB; 6GQV; EM; 4.00 A; AR=2-82. DR PDB; 6HHQ; X-ray; 3.10 A; c/d7=1-82. DR PDB; 6I7O; EM; 5.30 A; f/fb=2-82. DR PDB; 6KE6; EM; 3.40 A; Sc=1-82. DR PDB; 6LQP; EM; 3.20 A; Sc=1-82. DR PDB; 6LQQ; EM; 4.10 A; Sc=1-82. DR PDB; 6LQR; EM; 8.60 A; Sc=1-82. DR PDB; 6LQS; EM; 3.80 A; Sc=1-82. DR PDB; 6LQT; EM; 4.90 A; Sc=1-82. DR PDB; 6Q8Y; EM; 3.10 A; f=2-82. DR PDB; 6RBD; EM; 3.47 A; b=1-82. DR PDB; 6RBE; EM; 3.80 A; b=1-82. DR PDB; 6S47; EM; 3.28 A; Bc=2-82. DR PDB; 6SNT; EM; 2.80 A; b=1-82. DR PDB; 6SV4; EM; 3.30 A; f/fb/fc=1-82. DR PDB; 6T4Q; EM; 2.60 A; Sb=2-82. DR PDB; 6T7I; EM; 3.20 A; Sb=1-82. DR PDB; 6T7T; EM; 3.10 A; Sb=2-82. DR PDB; 6T83; EM; 4.00 A; 2/bb=1-82. DR PDB; 6TB3; EM; 2.80 A; f=2-82. DR PDB; 6TNU; EM; 3.10 A; f=2-82. DR PDB; 6WDR; EM; 3.70 A; b=2-82. DR PDB; 6WOO; EM; 2.90 A; bb=2-82. DR PDB; 6XIQ; EM; 4.20 A; AR=1-82. DR PDB; 6XIR; EM; 3.20 A; AR=1-82. DR PDB; 6Y7C; EM; 3.80 A; b=1-82. DR PDB; 6Z6J; EM; 3.40 A; Sb=1-82. DR PDB; 6Z6K; EM; 3.40 A; Sb=1-82. DR PDB; 6ZCE; EM; 5.30 A; c=1-82. DR PDB; 6ZQA; EM; 4.40 A; Db=1-82. DR PDB; 6ZQB; EM; 3.90 A; Db=1-82. DR PDB; 6ZQC; EM; 3.80 A; Db=1-82. DR PDB; 6ZQD; EM; 3.80 A; Db=1-82. DR PDB; 6ZQE; EM; 7.10 A; Db=1-82. DR PDB; 6ZQF; EM; 4.90 A; Db=1-82. DR PDB; 6ZQG; EM; 3.50 A; Db=1-82. DR PDB; 6ZU9; EM; 6.20 A; f=1-82. DR PDB; 6ZVI; EM; 3.00 A; L=2-82. DR PDB; 7A1G; EM; 3.00 A; f=2-82. DR PDB; 7AJT; EM; 4.60 A; Db=1-82. DR PDB; 7AJU; EM; 3.80 A; Db=1-82. DR PDB; 7B7D; EM; 3.30 A; f=2-82. DR PDB; 7D4I; EM; 4.00 A; Sc=1-82. DR PDB; 7D5T; EM; 6.00 A; Sc=1-82. DR PDB; 7D63; EM; 12.30 A; Sc=1-82. DR PDB; 7MPI; EM; 3.05 A; Bb=2-82. DR PDB; 7MPJ; EM; 2.70 A; Bb=2-82. DR PDB; 7N8B; EM; 3.05 A; Bb=2-82. DR PDB; 7NRC; EM; 3.90 A; Sf=2-82. DR PDB; 7NRD; EM; 4.36 A; Sf=2-82. DR PDB; 7OSA; X-ray; 3.00 A; eS27=1-82. DR PDB; 7OSM; X-ray; 3.00 A; eS27=1-82. DR PDB; 7RR5; EM; 3.23 A; Sb=1-82. DR PDB; 7WTL; EM; 3.30 A; Sb=1-82. DR PDB; 7WTM; EM; 3.50 A; Sb=1-82. DR PDB; 7WTN; EM; 3.40 A; Sb=1-82. DR PDB; 7WTO; EM; 3.50 A; Sb=1-82. DR PDB; 7WTP; EM; 3.80 A; Sb=1-82. DR PDB; 7WTQ; EM; 3.70 A; Sb=1-82. DR PDB; 7WTR; EM; 3.50 A; Sb=1-82. DR PDB; 7ZPQ; EM; 3.47 A; Ab=2-82. DR PDB; 7ZRS; EM; 4.80 A; Ab=2-82. DR PDB; 7ZUW; EM; 4.30 A; Ab=2-82. DR PDB; 7ZUX; EM; 2.50 A; Db=2-82. DR PDB; 7ZW0; EM; 2.40 A; sf=1-82. DR PDB; 8BN3; EM; 2.40 A; D7=2-82. DR PDB; 8BQD; EM; 3.90 A; f=2-82. DR PDB; 8BQX; EM; 3.80 A; f=2-82. DR PDB; 8C00; EM; 2.90 A; f=1-82. DR PDB; 8C01; EM; 2.70 A; f=1-82. DR PDB; 8C83; EM; 3.00 A; f=1-82. DR PDB; 8CAH; EM; 3.00 A; f=1-82. DR PDB; 8CAS; EM; 3.30 A; f=1-82. DR PDB; 8CBJ; EM; 3.80 A; b=1-82. DR PDB; 8CCS; EM; 1.97 A; 3=1-82. DR PDB; 8CDL; EM; 2.72 A; 3=1-82. DR PDB; 8CDR; EM; 2.04 A; 3=1-82. DR PDB; 8CEH; EM; 2.05 A; 3=1-82. DR PDB; 8CF5; EM; 2.71 A; 3=1-82. DR PDB; 8CG8; EM; 2.57 A; 3=1-82. DR PDB; 8CGN; EM; 2.28 A; 3=1-82. DR PDB; 8CIV; EM; 2.47 A; 3=1-82. DR PDB; 8CKU; EM; 3.11 A; 3=1-82. DR PDB; 8CMJ; EM; 3.79 A; 3=1-82. DR PDB; 8EUB; EM; 2.52 A; Bb=1-82. DR PDB; 8EVP; EM; 2.38 A; Bb=1-82. DR PDB; 8EVQ; EM; 2.72 A; Bb=1-82. DR PDB; 8EVR; EM; 2.87 A; Bb=1-82. DR PDB; 8EVS; EM; 2.62 A; Bb=1-82. DR PDB; 8EVT; EM; 2.20 A; Bb=1-82. DR PDB; 8EWB; EM; 2.87 A; Bb=1-82. DR PDB; 8EWC; EM; 2.45 A; Bb=1-82. DR PDB; 8K2D; EM; 3.20 A; Sb=1-82. DR PDB; 8K82; EM; 3.00 A; Sb=1-82. DR PDB; 8P4V; X-ray; 3.16 A; c/d7=1-82. DR PDB; 8P85; X-ray; 2.90 A; c/d7=1-82. DR PDB; 8P9A; X-ray; 2.90 A; c/d7=1-82. DR PDB; 8PNN; X-ray; 2.90 A; c/d7=1-82. DR PDB; 8T2X; EM; 2.46 A; Bb=1-82. DR PDB; 8T2Y; EM; 2.20 A; Bb=1-82. DR PDB; 8T2Z; EM; 2.40 A; Bb=1-82. DR PDB; 8T30; EM; 2.88 A; Bb=1-82. DR PDB; 8T3A; EM; 2.86 A; Bb=1-82. DR PDB; 8T3B; EM; 3.08 A; Bb=1-82. DR PDB; 8T3C; EM; 3.86 A; Bb=1-82. DR PDB; 8T3D; EM; 2.95 A; Bb=1-82. DR PDB; 8T3E; EM; 3.04 A; Bb=1-82. DR PDB; 8T3F; EM; 3.09 A; Bb=1-82. DR PDB; 8UT0; EM; 3.22 A; Sf=2-82. DR PDB; 8UTI; EM; 3.13 A; Sf=2-82. DR PDB; 8XU8; EM; 3.40 A; Sf=2-82. DR PDB; 8Y0U; EM; 3.59 A; Sb=1-82. DR PDB; 8YLD; EM; 3.90 A; Sf=2-82. DR PDB; 8YLR; EM; 3.90 A; Sf=2-82. DR PDB; 8Z70; EM; 3.20 A; Sf=2-82. DR PDB; 8Z71; EM; 3.60 A; Sf=2-82. DR PDB; 8ZGR; EM; 2.70 A; Sf=2-82. DR PDB; 8ZGY; EM; 2.80 A; Sf=2-82. DR PDB; 8ZH3; EM; 2.70 A; Sf=2-82. DR PDB; 8ZHB; EM; 2.60 A; Sf=2-82. DR PDB; 8ZHC; EM; 2.30 A; Sf=2-82. DR PDB; 9F9S; EM; 2.90 A; RB/SB=1-82. DR PDB; 9N6V; EM; 3.16 A; NQ=1-82. DR PDB; 9N6W; EM; 3.05 A; NQ=1-82. DR PDB; 9N6X; EM; 3.71 A; NQ=1-82. DR PDB; 9N6Y; EM; 3.65 A; NQ=1-82. DR PDB; 9N6Z; EM; 4.74 A; NQ=1-82. DR PDB; 9N70; EM; 5.17 A; NQ=1-82. DR PDB; 9N72; EM; 5.94 A; NQ=1-82. DR PDB; 9N73; EM; 5.96 A; NQ=1-82. DR PDB; 9N74; EM; 2.65 A; NQ=1-82. DR PDB; 9N75; EM; 3.01 A; NQ=1-82. DR PDB; 9N76; EM; 4.20 A; NQ=1-82. DR PDB; 9N77; EM; 3.94 A; NQ=1-82. DR PDB; 9N78; EM; 4.17 A; NQ=1-82. DR PDB; 9N79; EM; 3.93 A; NQ=1-82. DR PDB; 9N7A; EM; 3.84 A; NQ=1-82. DR PDB; 9N7B; EM; 3.25 A; NQ=1-82. DR PDB; 9R9O; EM; 2.90 A; Sb=1-82. DR PDB; 9R9P; EM; 3.00 A; Sb=1-82. DR AlphaFoldDB; P35997; -. DR EMDB; EMD-0047; -. DR EMDB; EMD-0048; -. DR EMDB; EMD-0049; -. DR EMDB; EMD-0949; -. DR EMDB; EMD-0950; -. DR EMDB; EMD-0951; -. DR EMDB; EMD-0952; -. DR EMDB; EMD-0953; -. DR EMDB; EMD-10098; -. DR EMDB; EMD-10262; -. DR EMDB; EMD-10315; -. DR EMDB; EMD-10377; -. DR EMDB; EMD-10396; -. DR EMDB; EMD-10397; -. DR EMDB; EMD-10398; -. DR EMDB; EMD-10431; -. DR EMDB; EMD-10537; -. DR EMDB; EMD-10713; -. DR EMDB; EMD-11096; -. DR EMDB; EMD-11097; -. DR EMDB; EMD-11160; -. DR EMDB; EMD-11357; -. DR EMDB; EMD-11358; -. DR EMDB; EMD-11359; -. DR EMDB; EMD-11360; -. DR EMDB; EMD-11361; -. DR EMDB; EMD-11362; -. DR EMDB; EMD-11363; -. DR EMDB; EMD-11439; -. DR EMDB; EMD-11457; -. DR EMDB; EMD-11608; -. DR EMDB; EMD-11807; -. DR EMDB; EMD-11808; -. DR EMDB; EMD-12081; -. DR EMDB; EMD-12534; -. DR EMDB; EMD-12535; -. DR EMDB; EMD-14861; -. DR EMDB; EMD-14921; -. DR EMDB; EMD-14978; -. DR EMDB; EMD-14979; -. DR EMDB; EMD-14990; -. DR EMDB; EMD-16127; -. DR EMDB; EMD-16182; -. DR EMDB; EMD-16191; -. DR EMDB; EMD-16347; -. DR EMDB; EMD-16349; -. DR EMDB; EMD-16470; -. DR EMDB; EMD-16525; -. DR EMDB; EMD-16533; -. DR EMDB; EMD-16541; -. DR EMDB; EMD-16563; -. DR EMDB; EMD-16591; -. DR EMDB; EMD-16594; -. DR EMDB; EMD-16609; -. DR EMDB; EMD-16616; -. DR EMDB; EMD-16634; -. DR EMDB; EMD-16648; -. DR EMDB; EMD-16684; -. DR EMDB; EMD-16702; -. DR EMDB; EMD-16729; -. DR EMDB; EMD-21644; -. DR EMDB; EMD-21859; -. DR EMDB; EMD-22196; -. DR EMDB; EMD-22198; -. DR EMDB; EMD-23934; -. DR EMDB; EMD-23935; -. DR EMDB; EMD-24235; -. DR EMDB; EMD-24652; -. DR EMDB; EMD-28610; -. DR EMDB; EMD-28632; -. DR EMDB; EMD-28633; -. DR EMDB; EMD-28634; -. DR EMDB; EMD-28635; -. DR EMDB; EMD-28636; -. DR EMDB; EMD-28642; -. DR EMDB; EMD-28643; -. DR EMDB; EMD-30574; -. DR EMDB; EMD-30585; -. DR EMDB; EMD-30588; -. DR EMDB; EMD-32790; -. DR EMDB; EMD-32791; -. DR EMDB; EMD-32792; -. DR EMDB; EMD-32793; -. DR EMDB; EMD-32794; -. DR EMDB; EMD-32795; -. DR EMDB; EMD-32796; -. DR EMDB; EMD-3461; -. DR EMDB; EMD-36839; -. DR EMDB; EMD-36945; -. DR EMDB; EMD-38660; -. DR EMDB; EMD-40990; -. DR EMDB; EMD-40991; -. DR EMDB; EMD-40992; -. DR EMDB; EMD-40993; -. DR EMDB; EMD-40997; -. DR EMDB; EMD-40998; -. DR EMDB; EMD-40999; -. DR EMDB; EMD-41000; -. DR EMDB; EMD-41001; -. DR EMDB; EMD-41002; -. DR EMDB; EMD-4140; -. DR EMDB; EMD-4214; -. DR EMDB; EMD-42525; -. DR EMDB; EMD-42540; -. DR EMDB; EMD-4427; -. DR EMDB; EMD-4474; -. DR EMDB; EMD-4792; -. DR EMDB; EMD-4793; -. DR EMDB; EMD-49075; -. DR EMDB; EMD-49076; -. DR EMDB; EMD-49077; -. DR EMDB; EMD-49078; -. DR EMDB; EMD-49079; -. DR EMDB; EMD-49080; -. DR EMDB; EMD-49082; -. DR EMDB; EMD-49083; -. DR EMDB; EMD-49084; -. DR EMDB; EMD-49085; -. DR EMDB; EMD-49086; -. DR EMDB; EMD-49087; -. DR EMDB; EMD-49088; -. DR EMDB; EMD-49089; -. DR EMDB; EMD-49090; -. DR EMDB; EMD-49091; -. DR EMDB; EMD-50259; -. DR EMDB; EMD-53860; -. DR EMDB; EMD-53861; -. DR EMDB; EMD-60088; -. DR EMDB; EMD-60091; -. DR EMDB; EMD-60094; -. DR EMDB; EMD-60097; -. DR EMDB; EMD-60098; -. DR EMDB; EMD-6695; -. DR EMDB; EMD-6696; -. DR EMDB; EMD-9964; -. DR SMR; P35997; -. DR BioGRID; 33981; 739. DR ComplexPortal; CPX-1599; 40S cytosolic small ribosomal subunit. DR FunCoup; P35997; 1041. DR IntAct; P35997; 34. DR MINT; P35997; -. DR STRING; 4932.YKL156W; -. DR iPTMnet; P35997; -. DR PaxDb; 4932-YKL156W; -. DR PeptideAtlas; P35997; -. DR TopDownProteomics; P35997; -. DR EnsemblFungi; YKL156W_mRNA; YKL156W; YKL156W. DR GeneID; 853700; -. DR KEGG; sce:YKL156W; -. DR AGR; SGD:S000001639; -. DR SGD; S000001639; RPS27A. DR VEuPathDB; FungiDB:YKL156W; -. DR eggNOG; KOG1779; Eukaryota. DR HOGENOM; CLU_130128_3_0_1; -. DR InParanoid; P35997; -. DR OMA; IRSCARI; -. DR OrthoDB; 5567124at2759; -. DR BioCyc; YEAST:G3O-31926-MONOMER; -. DR Reactome; R-SCE-156827; L13a-mediated translational silencing of Ceruloplasmin expression. DR Reactome; R-SCE-1799339; SRP-dependent cotranslational protein targeting to membrane. DR Reactome; R-SCE-6791226; Major pathway of rRNA processing in the nucleolus and cytosol. DR Reactome; R-SCE-72649; Translation initiation complex formation. DR Reactome; R-SCE-72689; Formation of a pool of free 40S subunits. DR Reactome; R-SCE-72695; Formation of the ternary complex, and subsequently, the 43S complex. DR Reactome; R-SCE-72702; Ribosomal scanning and start codon recognition. DR Reactome; R-SCE-72706; GTP hydrolysis and joining of the 60S ribosomal subunit. DR Reactome; R-SCE-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC). DR Reactome; R-SCE-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC). DR Reactome; R-SCE-9954714; PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA. DR BioGRID-ORCS; 853700; 0 hits in 10 CRISPR screens. DR PRO; PR:P35997; -. DR Proteomes; UP000002311; Chromosome XI. DR RNAct; P35997; protein. DR GO; GO:0005737; C:cytoplasm; EXP:UniProtKB. DR GO; GO:0005829; C:cytosol; TAS:Reactome. DR GO; GO:0022627; C:cytosolic small ribosomal subunit; IDA:SGD. DR GO; GO:0003735; F:structural constituent of ribosome; IDA:SGD. DR GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IGI:SGD. DR GO; GO:0000028; P:ribosomal small subunit assembly; IMP:SGD. DR GO; GO:0006364; P:rRNA processing; IBA:GO_Central. DR GO; GO:0006412; P:translation; IBA:GO_Central. DR FunFam; 2.20.25.100:FF:000001; 40S ribosomal protein S27; 1. DR Gene3D; 2.20.25.100; Zn-binding ribosomal proteins; 1. DR HAMAP; MF_00371; Ribosomal_eS27; 1. DR InterPro; IPR000592; Ribosomal_eS27. DR InterPro; IPR023407; Ribosomal_eS27_Zn-bd_dom_sf. DR InterPro; IPR011332; Ribosomal_zn-bd. DR PANTHER; PTHR11594; 40S RIBOSOMAL PROTEIN S27; 1. DR Pfam; PF01667; Ribosomal_S27e; 1. DR SUPFAM; SSF57829; Zn-binding ribosomal proteins; 1. DR PROSITE; PS01168; RIBOSOMAL_S27E; 1. DR PDBsum; 3J6X; -. DR PDBsum; 3J6Y; -. DR PDBsum; 3J77; -. DR PDBsum; 3J78; -. DR PDBsum; 4U3M; -. DR PDBsum; 4U3N; -. DR PDBsum; 4U3U; -. DR PDBsum; 4U4N; -. DR PDBsum; 4U4O; -. DR PDBsum; 4U4Q; -. DR PDBsum; 4U4R; -. DR PDBsum; 4U4U; -. DR PDBsum; 4U4Y; -. DR PDBsum; 4U4Z; -. DR PDBsum; 4U50; -. DR PDBsum; 4U51; -. DR PDBsum; 4U52; -. DR PDBsum; 4U53; -. DR PDBsum; 4U55; -. DR PDBsum; 4U56; -. DR PDBsum; 4U6F; -. DR PDBsum; 4V6I; -. DR PDBsum; 4V88; -. DR PDBsum; 4V8Y; -. DR PDBsum; 4V8Z; -. DR PDBsum; 4V92; -. DR PDBsum; 5DAT; -. DR PDBsum; 5DC3; -. DR PDBsum; 5DGE; -. DR PDBsum; 5DGF; -. DR PDBsum; 5DGV; -. DR PDBsum; 5FCI; -. DR PDBsum; 5FCJ; -. DR PDBsum; 5I4L; -. DR PDBsum; 5JUO; -. DR PDBsum; 5JUP; -. DR PDBsum; 5JUS; -. DR PDBsum; 5JUT; -. DR PDBsum; 5JUU; -. DR PDBsum; 5LL6; -. DR PDBsum; 5LYB; -. DR PDBsum; 5M1J; -. DR PDBsum; 5MC6; -. DR PDBsum; 5MEI; -. DR PDBsum; 5NDG; -. DR PDBsum; 5NDV; -. DR PDBsum; 5NDW; -. DR PDBsum; 5OBM; -. DR PDBsum; 5ON6; -. DR PDBsum; 5TBW; -. DR PDBsum; 5TGA; -. DR PDBsum; 5TGM; -. DR PDBsum; 5WYJ; -. DR PDBsum; 5WYK; -. DR PDBsum; 6EML; -. DR PDBsum; 6FAI; -. DR PDBsum; 6GQ1; -. DR PDBsum; 6GQB; -. DR PDBsum; 6GQV; -. DR PDBsum; 6HHQ; -. DR PDBsum; 6I7O; -. DR PDBsum; 6KE6; -. DR PDBsum; 6LQP; -. DR PDBsum; 6LQQ; -. DR PDBsum; 6LQR; -. DR PDBsum; 6LQS; -. DR PDBsum; 6LQT; -. DR PDBsum; 6Q8Y; -. DR PDBsum; 6RBD; -. DR PDBsum; 6RBE; -. DR PDBsum; 6S47; -. DR PDBsum; 6SNT; -. DR PDBsum; 6SV4; -. DR PDBsum; 6T4Q; -. DR PDBsum; 6T7I; -. DR PDBsum; 6T7T; -. DR PDBsum; 6T83; -. DR PDBsum; 6TB3; -. DR PDBsum; 6TNU; -. DR PDBsum; 6WDR; -. DR PDBsum; 6WOO; -. DR PDBsum; 6XIQ; -. DR PDBsum; 6XIR; -. DR PDBsum; 6Y7C; -. DR PDBsum; 6Z6J; -. DR PDBsum; 6Z6K; -. DR PDBsum; 6ZCE; -. DR PDBsum; 6ZQA; -. DR PDBsum; 6ZQB; -. DR PDBsum; 6ZQC; -. DR PDBsum; 6ZQD; -. DR PDBsum; 6ZQE; -. DR PDBsum; 6ZQF; -. DR PDBsum; 6ZQG; -. DR PDBsum; 6ZU9; -. DR PDBsum; 6ZVI; -. DR PDBsum; 7A1G; -. DR PDBsum; 7AJT; -. DR PDBsum; 7AJU; -. DR PDBsum; 7B7D; -. DR PDBsum; 7D4I; -. DR PDBsum; 7D5T; -. DR PDBsum; 7D63; -. DR PDBsum; 7MPI; -. DR PDBsum; 7MPJ; -. DR PDBsum; 7N8B; -. DR PDBsum; 7NRC; -. DR PDBsum; 7NRD; -. DR PDBsum; 7OSA; -. DR PDBsum; 7OSM; -. DR PDBsum; 7RR5; -. DR PDBsum; 7WTL; -. DR PDBsum; 7WTM; -. DR PDBsum; 7WTN; -. DR PDBsum; 7WTO; -. DR PDBsum; 7WTP; -. DR PDBsum; 7WTQ; -. DR PDBsum; 7WTR; -. DR PDBsum; 7ZPQ; -. DR PDBsum; 7ZRS; -. DR PDBsum; 7ZUW; -. DR PDBsum; 7ZUX; -. DR PDBsum; 7ZW0; -. DR PDBsum; 8BN3; -. DR PDBsum; 8BQD; -. DR PDBsum; 8BQX; -. DR PDBsum; 8C00; -. DR PDBsum; 8C01; -. DR PDBsum; 8C83; -. DR PDBsum; 8CAH; -. DR PDBsum; 8CAS; -. DR PDBsum; 8CBJ; -. DR PDBsum; 8CCS; -. DR PDBsum; 8CDL; -. DR PDBsum; 8CDR; -. DR PDBsum; 8CEH; -. DR PDBsum; 8CF5; -. DR PDBsum; 8CG8; -. DR PDBsum; 8CGN; -. DR PDBsum; 8CIV; -. DR PDBsum; 8CKU; -. DR PDBsum; 8CMJ; -. DR PDBsum; 8EUB; -. DR PDBsum; 8EVP; -. DR PDBsum; 8EVQ; -. DR PDBsum; 8EVR; -. DR PDBsum; 8EVS; -. DR PDBsum; 8EVT; -. DR PDBsum; 8EWB; -. DR PDBsum; 8EWC; -. DR PDBsum; 8K2D; -. DR PDBsum; 8K82; -. DR PDBsum; 8P4V; -. DR PDBsum; 8P85; -. DR PDBsum; 8P9A; -. DR PDBsum; 8PNN; -. DR PDBsum; 8T2X; -. DR PDBsum; 8T2Y; -. DR PDBsum; 8T2Z; -. DR PDBsum; 8T30; -. DR PDBsum; 8T3A; -. DR PDBsum; 8T3B; -. DR PDBsum; 8T3C; -. DR PDBsum; 8T3D; -. DR PDBsum; 8T3E; -. DR PDBsum; 8T3F; -. DR PDBsum; 8UT0; -. DR PDBsum; 8UTI; -. DR PDBsum; 8XU8; -. DR PDBsum; 8Y0U; -. DR PDBsum; 8YLD; -. DR PDBsum; 8YLR; -. DR PDBsum; 8Z70; -. DR PDBsum; 8Z71; -. DR PDBsum; 8ZGR; -. DR PDBsum; 8ZGY; -. DR PDBsum; 8ZH3; -. DR PDBsum; 8ZHB; -. DR PDBsum; 8ZHC; -. DR PDBsum; 9F9S; -. DR PDBsum; 9N6V; -. DR PDBsum; 9N6W; -. DR PDBsum; 9N6X; -. DR PDBsum; 9N6Y; -. DR PDBsum; 9N6Z; -. DR PDBsum; 9N70; -. DR PDBsum; 9N72; -. DR PDBsum; 9N73; -. DR PDBsum; 9N74; -. DR PDBsum; 9N75; -. DR PDBsum; 9N76; -. DR PDBsum; 9N77; -. DR PDBsum; 9N78; -. DR PDBsum; 9N79; -. DR PDBsum; 9N7A; -. DR PDBsum; 9N7B; -. DR PDBsum; 9R9O; -. DR PDBsum; 9R9P; -. PE 1: Evidence at protein level; KW 3D-structure; Cytoplasm; Metal-binding; Methylation; Reference proteome; KW Ribonucleoprotein; Ribosomal protein; Zinc; Zinc-finger. FT CHAIN 1..82 FT /note="Small ribosomal subunit protein eS27A" FT /id="PRO_0000149066" FT ZN_FING 37..59 FT /note="C4-type" FT /evidence="ECO:0000255" FT MOD_RES 40 FT /note="S-methylcysteine" FT /evidence="ECO:0000269|PubMed:22650761" FT STRAND 7..9 FT /evidence="ECO:0007829|PDB:8CCS" FT HELIX 12..17 FT /evidence="ECO:0007829|PDB:8CCS" FT TURN 20..22 FT /evidence="ECO:0007829|PDB:8CCS" FT STRAND 23..25 FT /evidence="ECO:0007829|PDB:8CCS" FT STRAND 32..36 FT /evidence="ECO:0007829|PDB:8CCS" FT STRAND 38..41 FT /evidence="ECO:0007829|PDB:8CGN" FT STRAND 43..47 FT /evidence="ECO:0007829|PDB:8CCS" FT HELIX 54..56 FT /evidence="ECO:0007829|PDB:8PNN" FT STRAND 57..59 FT /evidence="ECO:0007829|PDB:8EVT" FT STRAND 63..65 FT /evidence="ECO:0007829|PDB:8EVT" FT STRAND 68..70 FT /evidence="ECO:0007829|PDB:8CCS" FT STRAND 73..76 FT /evidence="ECO:0007829|PDB:5JUP" FT STRAND 79..81 FT /evidence="ECO:0007829|PDB:8CCS" SQ SEQUENCE 82 AA; 8879 MW; FCA80130CFCEC91E CRC64; MVLVQDLLHP TAASEARKHK LKTLVQGPRS YFLDVKCPGC LNITTVFSHA QTAVTCESCS TILCTPTGGK AKLSEGTSFR RK //