ID   DCRA_NITV2              Reviewed;         669 AA.
AC   P35841;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2004, sequence version 2.
DT   02-SEP-2026, entry version 162.
DE   RecName: Full=Chemoreceptor protein A;
GN   Name=dcrA; OrderedLocusNames=DVU_3182;
OS   Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 /
OS   NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris).
OC   Bacteria; Pseudomonadati; Thermodesulfobacteriota; Desulfovibrionia;
OC   Desulfovibrionales; Desulfovibrionaceae; Nitratidesulfovibrio.
OX   NCBI_TaxID=882;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1548224; DOI=10.1128/jb.174.6.1726-1733.1992;
RA   Dolla A., Fu R., Brumlik M.J., Voordouw G.;
RT   "Nucleotide sequence of dcrA, a Desulfovibrio vulgaris Hildenborough
RT   chemoreceptor gene, and its expression in Escherichia coli.";
RL   J. Bacteriol. 174:1726-1733(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 /
RC   Hildenborough;
RX   PubMed=15077118; DOI=10.1038/nbt959;
RA   Heidelberg J.F., Seshadri R., Haveman S.A., Hemme C.L., Paulsen I.T.,
RA   Kolonay J.F., Eisen J.A., Ward N.L., Methe B.A., Brinkac L.M.,
RA   Daugherty S.C., DeBoy R.T., Dodson R.J., Durkin A.S., Madupu R.,
RA   Nelson W.C., Sullivan S.A., Fouts D.E., Haft D.H., Selengut J.,
RA   Peterson J.D., Davidsen T.M., Zafar N., Zhou L., Radune D., Dimitrov G.,
RA   Hance M., Tran K., Khouri H.M., Gill J., Utterback T.R., Feldblyum T.V.,
RA   Wall J.D., Voordouw G., Fraser C.M.;
RT   "The genome sequence of the anaerobic, sulfate-reducing bacterium
RT   Desulfovibrio vulgaris Hildenborough.";
RL   Nat. Biotechnol. 22:554-559(2004).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}; Periplasmic side {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000305}.
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DR   EMBL; M81168; AAA23379.1; -; Genomic_DNA.
DR   EMBL; AE017285; AAS97652.1; -; Genomic_DNA.
DR   PIR; A42275; A42275.
DR   RefSeq; WP_010940440.1; NC_002937.3.
DR   AlphaFoldDB; P35841; -.
DR   SMR; P35841; -.
DR   STRING; 882.DVU_3182; -.
DR   PaxDb; 882-DVU_3182; -.
DR   EnsemblBacteria; AAS97652; AAS97652; DVU_3182.
DR   KEGG; dvu:DVU_3182; -.
DR   PATRIC; fig|882.5.peg.2887; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_27_7; -.
DR   OrthoDB; 9816383at2; -.
DR   PhylomeDB; P35841; -.
DR   Proteomes; UP000002194; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   CDD; cd00130; PAS; 1.
DR   FunFam; 1.10.287.950:FF:000001; Methyl-accepting chemotaxis sensory transducer; 1.
DR   Gene3D; 3.30.450.290; -; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013767; PAS_fold.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR32089:SF112; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   Pfam; PF00989; PAS; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 2.
DR   SMART; SM00283; MA; 1.
DR   SMART; SM00086; PAC; 1.
DR   SMART; SM00091; PAS; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
DR   PROSITE; PS50113; PAC; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Chemotaxis; Membrane; Methylation; Reference proteome;
KW   Transducer; Transmembrane; Transmembrane helix.
FT   CHAIN           1..669
FT                   /note="Chemoreceptor protein A"
FT                   /id="PRO_0000110564"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          209..261
FT                   /note="HAMP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00102"
FT   DOMAIN          330..382
FT                   /note="PAC"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00141"
FT   DOMAIN          397..633
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00284"
FT   CONFLICT        248
FT                   /note="N -> K (in Ref. 1; AAA23379)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        456..460
FT                   /note="LANGE -> CQWR (in Ref. 1; AAA23379)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        536
FT                   /note="V -> L (in Ref. 1; AAA23379)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        638..649
FT                   /note="GIQRRVREAGDA -> ASRDGCGKQAMP (in Ref. 1; AAA23379)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   669 AA;  72984 MW;  BB3079D58F3FF9A5 CRC64;
     MSTQRSLGTK VMLLVSGISL FVYLILAVLT SYWQRQSALT LIDSGAVRAS ELLLDAIADP
     MSKGNDTGTT EKFDAIARRY ADIRAYMTDF RGNITYSTSK DVLRRDLADV VQAPALLDKF
     NAALKTDSRE EQLATIDGMA FYATIRSIPN APECHHCHGR SQPILGTLVM LQDVTPAMSE
     LRLHQYETVG LSVGGLLLLV GVLSLFMRRA VISRVQRIAA VSGQIEQGDY SVSFEHDGND
     ELTRLNANLA SMVTTIRDQM QYNRSVLEGI IVPLAVVDAR NRIEFINQPM CTIVSTACHE
     YSGKDFSAFM QQGGVEEDIT ATVLKGGNNQ QGNISYRRDD GTVFPLHYEV SPLRDDRGAV
     NGAIAVIIDL TQEEEARRRI EEQRINLLRV ADEVTGVAET LVRAAEALVT RMGELERDAT
     EAASETTQVA TAMEEMNVTV TEVARNASST AEMADLANGE AQSGGTEMAN TVRETRQVAQ
     RTEDLAESLH ELARRADNIG RVIEVINEIA DQTNLLALNA AIEAARAGDA GRGFAVVADE
     VRKLAEKTMV ATREVEQAIA AIQQGSNDAV EVMTETRQQV EVTAGKAEDT GKVLSGIVGR
     AESIADMVRN IATASEQQSS TSDEINRNVT RINDLTEGIQ RRVREAGDAI RQVEGMAQRL
     EALVDGFRK
//