ID   COG3_CHIOP              Reviewed;          20 AA.
AC   P34155;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   02-SEP-2026, entry version 65.
DE   RecName: Full=Collagenolytic protease 36 kDa;
DE            EC=3.4.21.32;
DE   Flags: Fragment;
OS   Chionoecetes opilio (Atlantic snow crab) (Cancer opilio).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Altocrustacea; Communostraca;
OC   Malacostraca; Eumalacostraca; Stomatocarida; Decapoda; Pleocyemata;
OC   Brachyura; Eubrachyura; Majoidea; Majidae; Chionoecetes.
OX   NCBI_TaxID=41210;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Hepatopancreas;
RX   PubMed=1663026;
RA   Klimova O.A., Vedishcheva Y.V., Strongin A.Y.;
RT   "Isolation and characteristics of collagenolytic enzymes from the
RT   hepatopancreas of the crab Chionoecetes opilio.";
RL   Dokl. Akad. Nauk SSSR 317:482-484(1991).
CC   -!- FUNCTION: This enzyme is a serine protease capable of degrading the
CC       native triple helix of collagen.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of proteins, with broad specificity for peptide
CC         bonds. Native collagen is cleaved about 75% of the length of the
CC         molecule from the N-terminus. Low activity on small molecule
CC         substrates of both trypsin and chymotrypsin.; EC=3.4.21.32;
CC   -!- SIMILARITY: Belongs to the peptidase S1 family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00274}.
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DR   AlphaFoldDB; P34155; -.
DR   MEROPS; S01.122; -.
PE   1: Evidence at protein level;
KW   Collagen degradation; Direct protein sequencing; Hydrolase; Protease;
KW   Serine protease.
FT   CHAIN           1..>20
FT                   /note="Collagenolytic protease 36 kDa"
FT                   /id="PRO_0000088672"
FT   DOMAIN          1..>20
FT                   /note="Peptidase S1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00274"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         20
SQ   SEQUENCE   20 AA;  2116 MW;  45A172721B801016 CRC64;
     IVGGTEVTPG EIPYQLSLQD
//