ID   YFFB_ECOLI              Reviewed;         118 AA.
AC   P24178;
DT   01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-1992, sequence version 1.
DT   04-NOV-2026, entry version 159.
DE   RecName: Full=Protein YffB;
GN   Name=yffB; OrderedLocusNames=b2471, JW2455;
OS   Escherichia coli (strain K12).
OC   Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
OC   Enterobacterales; Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12;
RX   PubMed=1644752; DOI=10.1128/jb.174.16.5265-5271.1992;
RA   Bouvier J., Richaud C., Higgins W., Bogler O., Stragier S.;
RT   "Cloning, characterization, and expression of the dapE gene of Escherichia
RT   coli.";
RL   J. Bacteriol. 174:5265-5271(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=9205837; DOI=10.1093/dnares/4.2.91;
RA   Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T.,
RA   Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K.,
RA   Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T., Oyama S.,
RA   Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H.,
RA   Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.;
RT   "Construction of a contiguous 874-kb sequence of the Escherichia coli-K12
RT   genome corresponding to 50.0-68.8 min on the linkage map and analysis of
RT   its sequence features.";
RL   DNA Res. 4:91-113(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [5]
RP   IDENTIFICATION BY MASS SPECTROMETRY.
RC   STRAIN=B / BL21;
RX   PubMed=10493123;
RX   DOI=10.1002/(sici)1522-2683(19990801)20:11<2181::aid-elps2181>3.0.co;2-q;
RA   Fountoulakis M., Takacs M.-F., Berndt P., Langen H., Takacs B.;
RT   "Enrichment of low abundance proteins of Escherichia coli by hydroxyapatite
RT   chromatography.";
RL   Electrophoresis 20:2181-2195(1999).
CC   -!- SIMILARITY: Belongs to the ArsC family. {ECO:0000305}.
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DR   EMBL; X57403; CAA40664.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC75524.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA16345.1; -; Genomic_DNA.
DR   PIR; B42959; B42959.
DR   RefSeq; NP_416966.1; NC_000913.3.
DR   RefSeq; WP_000258236.1; NZ_CP009789.1.
DR   AlphaFoldDB; P24178; -.
DR   SMR; P24178; -.
DR   BioGRID; 4259194; 44.
DR   BioGRID; 851292; 7.
DR   DIP; DIP-12024N; -.
DR   FunCoup; P24178; 167.
DR   IntAct; P24178; 19.
DR   STRING; 511145.b2471; -.
DR   jPOST; P24178; -.
DR   PaxDb; 511145-b2471; -.
DR   EnsemblBacteria; AAC75524; AAC75524; b2471.
DR   GeneID; 946953; -.
DR   KEGG; ecj:JW2455; -.
DR   KEGG; eco:b2471; -.
DR   KEGG; ecoc:C3026_13710; -.
DR   PATRIC; fig|1411691.4.peg.4269; -.
DR   EchoBASE; EB1137; -.
DR   eggNOG; COG1393; Bacteria.
DR   HOGENOM; CLU_116644_2_1_6; -.
DR   InParanoid; P24178; -.
DR   OMA; AACDNQA; -.
DR   OrthoDB; 9803749at2; -.
DR   PhylomeDB; P24178; -.
DR   BioCyc; EcoCyc:EG11147-MONOMER; -.
DR   PRO; PR:P24178; -.
DR   Proteomes; UP000000625; Chromosome.
DR   AbasyAtlas; P24178; -.
DR   GO; GO:0005829; C:cytosol; IDA:EcoCyc.
DR   CDD; cd03035; ArsC_Yffb; 1.
DR   FunFam; 3.40.30.10:FF:000068; ArsC family reductase; 1.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR   InterPro; IPR006660; Arsenate_reductase-like.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR006504; Tscrpt_reg_Spx/MgsR.
DR   NCBIfam; TIGR01617; arsC_related; 1.
DR   NCBIfam; NF008107; PRK10853.1; 1.
DR   PANTHER; PTHR30041; ARSENATE REDUCTASE; 1.
DR   PANTHER; PTHR30041:SF8; PROTEIN YFFB; 1.
DR   Pfam; PF03960; ArsC; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 1.
DR   PROSITE; PS51353; ARSC; 1.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..118
FT                   /note="Protein YffB"
FT                   /id="PRO_0000169229"
FT   ACT_SITE        10
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01282"
SQ   SEQUENCE   118 AA;  13601 MW;  38DF13A158BEA275 CRC64;
     MVTLYGIKNC DTIKKARRWL EANNIDYRFH DYRVDGLDSE LLNDFINELG WEALLNTRGT
     TWRKLDETTR NKITDAASAA ALMTEMPAII KRPLLCVPGK PMLLGFSDSS YQQFFHEV
//