ID RL32_ARATH Reviewed; 390 AA. AC P22738; Q9SY92; DT 01-AUG-1991, integrated into UniProtKB/Swiss-Prot. DT 23-JAN-2007, sequence version 4. DT 02-SEP-2026, entry version 171. DE RecName: Full=Large ribosomal subunit protein uL3y {ECO:0000303|PubMed:36423343}; DE AltName: Full=60S ribosomal protein L3-2; GN Name=ARP2; Synonyms=RPL3B; OrderedLocusNames=At1g61580; GN ORFNames=T25B24.7; OS Arabidopsis thaliana (Mouse-ear cress). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis. OX NCBI_TaxID=3702; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RX PubMed=2227432; DOI=10.1016/0378-1119(90)90222-d; RA Kim Y., Zhang H., Scholl R.L.; RT "Two evolutionarily divergent genes encode a cytoplasmic ribosomal protein RT of Arabidopsis thaliana."; RL Gene 93:177-182(1990). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Columbia; RX PubMed=11130712; DOI=10.1038/35048500; RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L., RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., RA Yu G., Fraser C.M., Venter J.C., Davis R.W.; RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."; RL Nature 408:816-820(2000). RN [3] RP GENOME REANNOTATION. RC STRAIN=cv. Columbia; RX PubMed=27862469; DOI=10.1111/tpj.13415; RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S., RA Town C.D.; RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference RT genome."; RL Plant J. 89:789-804(2017). RN [4] RP GENOME REANNOTATION. RC STRAIN=cv. Columbia; RG The Arabidopsis Information Resource (TAIR); RT "Community-consensus reference genome of Arabidopsis thaliana Col-0."; RL Submitted (FEB-2026) to the EMBL/GenBank/DDBJ databases. RN [5] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=cv. Columbia; RX PubMed=14593172; DOI=10.1126/science.1088305; RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L., RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., RA Ecker J.R.; RT "Empirical analysis of transcriptional activity in the Arabidopsis RT genome."; RL Science 302:842-846(2003). RN [6] RP GENE FAMILY ORGANIZATION, AND NOMENCLATURE. RX PubMed=11598216; DOI=10.1104/pp.127.2.398; RA Barakat A., Szick-Miranda K., Chang I.-F., Guyot R., Blanc G., Cooke R., RA Delseny M., Bailey-Serres J.; RT "The organization of cytoplasmic ribosomal protein genes in the Arabidopsis RT genome."; RL Plant Physiol. 127:398-415(2001). RN [7] RP NOMENCLATURE. RX PubMed=36423343; DOI=10.1093/plcell/koac333; RA Scarpin M.R., Busche M., Martinez R.E., Harper L.C., Reiser L., RA Szakonyi D., Merchante C., Lan T., Xiong W., Mo B., Tang G., Chen X., RA Bailey-Serres J., Browning K.S., Brunkard J.O.; RT "An updated nomenclature for plant ribosomal protein genes."; RL Plant Cell 35:640-643(2023). CC -!- SUBCELLULAR LOCATION: Cytoplasm. CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL3 family. CC {ECO:0000305}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; M32655; AAA66161.1; -; Genomic_DNA. DR EMBL; AC005850; AAD25547.1; -; Genomic_DNA. DR EMBL; CP002684; AEE33859.1; -; Genomic_DNA. DR EMBL; OZ408683; CAO7031700.1; -; Genomic_DNA. DR EMBL; BT003869; AAO41918.1; -; mRNA. DR EMBL; BT005702; AAO64122.1; -; mRNA. DR PIR; B96641; B96641. DR PIR; JQ0772; JQ0772. DR RefSeq; NP_176352.1; NM_104840.5. DR AlphaFoldDB; P22738; -. DR SMR; P22738; -. DR BioGRID; 27677; 170. DR FunCoup; P22738; 2194. DR IntAct; P22738; 1. DR STRING; 3702.P22738; -. DR iPTMnet; P22738; -. DR PaxDb; 3702-P22738; -. DR ProteomicsDB; 236463; -. DR GeneID; 842454; -. DR KEGG; ath:AT1G61580; -. DR Araport; AT1G61580; -. DR TAIR; AT1G61580; RPL3B. DR eggNOG; KOG0746; Eukaryota. DR HOGENOM; CLU_033361_2_1_1; -. DR InParanoid; P22738; -. DR OMA; VDWARVK; -. DR PhylomeDB; P22738; -. DR CD-CODE; 4299E36E; Nucleolus. DR PRO; PR:P22738; -. DR Proteomes; UP000006548; Chromosome 1. DR GO; GO:0005737; C:cytoplasm; ISM:TAIR. DR GO; GO:0022625; C:cytosolic large ribosomal subunit; HDA:TAIR. DR GO; GO:0005634; C:nucleus; HDA:TAIR. DR GO; GO:0003735; F:structural constituent of ribosome; IDA:CAFA. DR GO; GO:0042742; P:defense response to bacterium; IEP:TAIR. DR GO; GO:0006412; P:translation; IBA:GO_Central. DR FunFam; 2.40.30.10:FF:000079; 60S ribosomal protein L3; 1. DR FunFam; 3.30.1430.10:FF:000001; 60S ribosomal protein L3; 1. DR FunFam; 4.10.960.10:FF:000001; 60S ribosomal protein L3; 1. DR FunFam; 4.10.960.10:FF:000002; 60S ribosomal protein L3; 1. DR FunFam; 2.40.30.10:FF:000351; Ribosomal protein L3; 1. DR Gene3D; 3.30.1430.10; -; 1. DR Gene3D; 4.10.960.10; Ribosomal protein L3, domain 3; 1. DR Gene3D; 2.40.30.10; Translation factors; 1. DR InterPro; IPR045077; L3_arc_euk. DR InterPro; IPR044892; Ribosomal_L3_dom_3_arc_sf. DR InterPro; IPR000597; Ribosomal_uL3. DR InterPro; IPR019926; Ribosomal_uL3_CS. DR InterPro; IPR009000; Transl_B-barrel_sf. DR PANTHER; PTHR11363; 60S RIBOSOMAL PROTEIN L3-RELATED; 1. DR PANTHER; PTHR11363:SF14; LARGE RIBOSOMAL SUBUNIT PROTEIN UL3Y; 1. DR Pfam; PF00297; Ribosomal_L3; 1. DR SUPFAM; SSF50447; Translation proteins; 1. DR PROSITE; PS00474; RIBOSOMAL_L3; 1. PE 2: Evidence at transcript level; KW Cytoplasm; Reference proteome; Ribonucleoprotein; Ribosomal protein. FT CHAIN 1..390 FT /note="Large ribosomal subunit protein uL3y" FT /id="PRO_0000077240" FT REGION 1..36 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 18..31 FT /note="Basic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT CONFLICT 174 FT /note="L -> V (in Ref. 1; AAA66161)" FT /evidence="ECO:0000305" SQ SEQUENCE 390 AA; 44546 MW; 1D9B17C2A953B27C CRC64; MSHRKFEHPR HGSLGFLPRK RASRHRGKVK AFPKDDPTKP CRLTSFLGYK AGMTHIVRDV EKPGSKLHKK ETCEAVTIIE TPPMVVVGVV GYVKTPRGLR SLCTVWAQHL SEELRRRFYK NWAKSKKKAF TRYSKKHETE EGKKDIQSQL EKMKKYCSVI RVLAHTQIRK MKGLKQKKAH LNEIQINGGD IAKKVDYACS LFEKQVPVDA IFQKDEMIDI IGVTKGKGYE GVVTRWGVTR LPRKTHRGLR KVACIGAWHP ARVSYTVARA GQNGYHHRTE MNKKVYRVGK VGQETHSAMT EYDRTEKDIT PMGGFPHYGI VKEDYLMIKG CCVGPKKRVV TLRQTLLKQT SRLAMEEIKL KFIDAASNGG HGRFQTSQEK AKFYGRTIKA //