ID RL18_ECOLI Reviewed; 117 AA. AC P0C018; P02419; Q2M6W9; DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot. DT 21-JUL-1986, sequence version 1. DT 04-NOV-2026, entry version 173. DE RecName: Full=Large ribosomal subunit protein uL18 {ECO:0000303|PubMed:24524803}; DE AltName: Full=50S ribosomal protein L18; GN Name=rplR; OrderedLocusNames=b3304, JW3266; OS Escherichia coli (strain K12). OC Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; OC Enterobacterales; Enterobacteriaceae; Escherichia. OX NCBI_TaxID=83333; RN [1] RP PROTEIN SEQUENCE, AND SUBUNIT. RC STRAIN=K; RX PubMed=1098937; DOI=10.1016/0014-5793(75)81127-6; RA Brosius J., Schiltz E., Chen R.; RT "The primary structure of the 5S RNA binding protein L18 from Escherichia RT coli ribosomes."; RL FEBS Lett. 56:359-361(1975). RN [2] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RC STRAIN=K12; RX PubMed=6222285; DOI=10.1093/nar/11.9.2599; RA Cerretti D.P., Dean D., Davis G.R., Bedwell D.M., Nomura M.; RT "The spc ribosomal protein operon of Escherichia coli: sequence and RT cotranscription of the ribosomal protein genes and a protein export gene."; RL Nucleic Acids Res. 11:2599-2616(1983). RN [3] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=K12 / MG1655 / ATCC 47076; RX PubMed=9278503; DOI=10.1126/science.277.5331.1453; RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., RA Shao Y.; RT "The complete genome sequence of Escherichia coli K-12."; RL Science 277:1453-1462(1997). RN [4] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911; RX PubMed=16738553; DOI=10.1038/msb4100049; RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.; RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 RT and W3110."; RL Mol. Syst. Biol. 2:E1-E5(2006). RN [5] RP FORMATION OF THE 5S RRNA/L5/L18/L25 SUBCOMPLEX. RX PubMed=354687; DOI=10.1021/bi00606a002; RA Spierer P., Zimmermann R.A.; RT "Stoichiometry, cooperativity, and stability of interactions between 5S RNA RT and proteins L5, L18, and L25 from the 50S ribosomal subunit of Escherichia RT coli."; RL Biochemistry 17:2474-2479(1978). RN [6] RP FUNCTION OF THE BASIC N-TERMINUS. RX PubMed=353728; DOI=10.1093/nar/5.6.1753; RA Newberry V., Brosius J., Garrett R.; RT "Fragment of protein L18 from the Escherichia coli ribosome that contains RT the 5S RNA binding site."; RL Nucleic Acids Res. 5:1753-1766(1978). RN [7] RP ASSOCIATION OF 5S RRNA/L5/L18 WITH 23S RRNA. RC STRAIN=MRE-600; RX PubMed=109811; DOI=10.1093/nar/6.4.1669; RA Spierer P., Wang C.-C., Marsh T.L., Zimmermann R.A.; RT "Cooperative interactions among protein and RNA components of the 50S RT ribosomal subunit of Escherichia coli."; RL Nucleic Acids Res. 6:1669-1682(1979). RN [8] RP REQUIREMENT OF N-TERMINUS FOR FORMATION OF 5S RRNA-23S RRNA COMPLEX. RC STRAIN=MRE-600; RX PubMed=6159586; DOI=10.1093/nar/8.18.4131; RA Newberry V., Garrett R.A.; RT "The role of the basic N-terminal region of protein L18 in 5S RNA-23S RNA RT complex formation."; RL Nucleic Acids Res. 8:4131-4142(1980). RN [9] RP REQUIREMENT FOR INCORPORATION OF 5S RRNA INTO THE 50S SUBUNIT. RC STRAIN=MRE-600; RX PubMed=7038683; DOI=10.1073/pnas.79.3.729; RA Rohl R., Nierhaus K.H.; RT "Assembly map of the large subunit (50S) of Escherichia coli ribosomes."; RL Proc. Natl. Acad. Sci. U.S.A. 79:729-733(1982). RN [10] RP CHARACTERIZATION OF A 5S RRNA/L5/L18/L25 SUBCOMPLEX. RC STRAIN=K12 / A19; RX PubMed=8925931; DOI=10.1016/0014-5793(96)00872-1; RA Shpanchenko O.V., Zvereva M.I., Dontsova O.A., Nierhaus K.H., RA Bogdanov A.A.; RT "5S rRNA sugar-phosphate backbone protection in complexes with specific RT ribosomal proteins."; RL FEBS Lett. 394:71-75(1996). RN [11] RP PHOSPHORYLATION. RX PubMed=10529214; DOI=10.1021/bi9914816; RA Bloemink M.J., Moore P.B.; RT "Phosphorylation of ribosomal protein L18 is required for its folding and RT binding to 5S rRNA."; RL Biochemistry 38:13385-13390(1999). RN [12] RP MASS SPECTROMETRY, AND SUBUNIT. RC STRAIN=K12 / ATCC 25404 / DSM 5698 / NCIMB 11290; RX PubMed=10094780; DOI=10.1006/abio.1998.3077; RA Arnold R.J., Reilly J.P.; RT "Observation of Escherichia coli ribosomal proteins and their RT posttranslational modifications by mass spectrometry."; RL Anal. Biochem. 269:105-112(1999). RN [13] RP NOMENCLATURE. RX PubMed=24524803; DOI=10.1016/j.sbi.2014.01.002; RA Ban N., Beckmann R., Cate J.H.D., Dinman J.D., Dragon F., Ellis S.R., RA Lafontaine D.L.J., Lindahl L., Liljas A., Lipton J.M., McAlear M.A., RA Moore P.B., Noller H.F., Ortega J., Panse V.G., Ramakrishnan V., RA Spahn C.M.T., Steitz T.A., Tchorzewski M., Tollervey D., Warren A.J., RA Williamson J.R., Wilson D., Yonath A., Yusupov M.; RT "A new system for naming ribosomal proteins."; RL Curr. Opin. Struct. Biol. 24:165-169(2014). RN [14] RP STRUCTURE BY ELECTRON MICROSCOPY, AND SUBUNIT. RC STRAIN=MRE-600; RX PubMed=12809609; DOI=10.1016/s0092-8674(03)00427-6; RA Gao H., Sengupta J., Valle M., Korostelev A., Eswar N., Stagg S.M., RA Van Roey P., Agrawal R.K., Harvey S.C., Sali A., Chapman M.S., Frank J.; RT "Study of the structural dynamics of the E. coli 70S ribosome using real- RT space refinement."; RL Cell 113:789-801(2003). RN [15] RP X-RAY CRYSTALLOGRAPHY OF 2 DIFFERENT RIBOSOME STRUCTURES, AND SUBUNIT. RC STRAIN=MRE-600; RX PubMed=16272117; DOI=10.1126/science.1117230; RA Schuwirth B.S., Borovinskaya M.A., Hau C.W., Zhang W., Vila-Sanjurjo A., RA Holton J.M., Cate J.H.D.; RT "Structures of the bacterial ribosome at 3.5 A resolution."; RL Science 310:827-834(2005). RN [16] RP STRUCTURE BY ELECTRON MICROSCOPY IN TNAC-STALLED 50S RIBOSOMAL SUBUNIT, AND RP SUBUNIT. RC STRAIN=K12 / A19 / KC6; RX PubMed=25310980; DOI=10.1016/j.celrep.2014.09.011; RA Bischoff L., Berninghausen O., Beckmann R.; RT "Molecular basis for the ribosome functioning as an L-tryptophan sensor."; RL Cell Rep. 9:469-475(2014). RN [17] RP STRUCTURE BY ELECTRON MICROSCOPY OF 50S RIBOSOMAL SUBUNIT IN COMPLEX WITH RP OBGE AND GMP-PNP, AND SUBUNIT. RX PubMed=24844575; DOI=10.1371/journal.pbio.1001866; RA Feng B., Mandava C.S., Guo Q., Wang J., Cao W., Li N., Zhang Y., Zhang Y., RA Wang Z., Wu J., Sanyal S., Lei J., Gao N.; RT "Structural and functional insights into the mode of action of a RT universally conserved Obg GTPase."; RL PLoS Biol. 12:E1001866-E1001866(2014). RN [18] RP STRUCTURE BY ELECTRON MICROSCOPY OF 70S RIBOSOME IN COMPLEX WITH ARFA AND RP RF2, AND SUBUNIT. RX PubMed=27906160; DOI=10.1038/nature20822; RA Ma C., Kurita D., Li N., Chen Y., Himeno H., Gao N.; RT "Mechanistic insights into the alternative translation termination by ArfA RT and RF2."; RL Nature 541:550-553(2017). RN [19] RP STRUCTURE BY ELECTRON MICROSCOPY OF 70S RIBOSOME IN COMPLEX WITH ARFA AND RP RF2, AND SUBUNIT. RX PubMed=27906161; DOI=10.1038/nature20821; RA Huter P., Mueller C., Beckert B., Arenz S., Berninghausen O., Beckmann R., RA Wilson D.N.; RT "Structural basis for ArfA-RF2-mediated translation termination on mRNAs RT lacking stop codons."; RL Nature 541:546-549(2017). RN [20] RP STRUCTURE BY ELECTRON MICROSCOPY OF 70S RIBOSOME IN COMPLEX WITH ARFA AND RP RF2, AND SUBUNIT. RX PubMed=27934701; DOI=10.1126/science.aai9127; RA James N.R., Brown A., Gordiyenko Y., Ramakrishnan V.; RT "Translational termination without a stop codon."; RL Science 354:1437-1440(2016). RN [21] RP STRUCTURE BY ELECTRON MICROSCOPY OF 70S RIBOSOME IN COMPLEX WITH ARFA AND RP RF2, AND SUBUNIT. RX PubMed=28077875; DOI=10.1038/nature21053; RA Zeng F., Chen Y., Remis J., Shekhar M., Phillips J.C., Tajkhorshid E., RA Jin H.; RT "Structural basis of co-translational quality control by ArfA and RF2 bound RT to ribosome."; RL Nature 541:554-557(2017). CC -!- FUNCTION: This is one of the proteins that mediates the attachment of CC the 5S rRNA subcomplex onto the large ribosomal subunit where it forms CC part of the central protuberance. Binds stably to 5S rRNA; increases CC binding abilities of L5 in a cooperative fashion; both proteins CC together confer 23S rRNA binding. The 5S rRNA and some of its CC associated proteins might help stabilize positioning of ribosome-bound CC tRNAs. {ECO:0000269|PubMed:109811, ECO:0000269|PubMed:353728, CC ECO:0000269|PubMed:354687, ECO:0000269|PubMed:6159586, CC ECO:0000269|PubMed:7038683}. CC -!- SUBUNIT: Part of the 50S ribosomal subunit (PubMed:1098937, CC PubMed:10094780, PubMed:12809609, PubMed:16272117, PubMed:25310980, CC PubMed:24844575, PubMed:27934701, PubMed:27906160, PubMed:27906161); CC part of the 5S rRNA/L5/L18/L25 subcomplex (PubMed:109811, CC PubMed:353728, PubMed:354687, PubMed:6159586, PubMed:7038683, CC PubMed:8925931). Contacts the 5S and 23S rRNAs. CC {ECO:0000269|PubMed:10094780, ECO:0000269|PubMed:109811, CC ECO:0000269|PubMed:1098937, ECO:0000269|PubMed:12809609, CC ECO:0000269|PubMed:16272117, ECO:0000269|PubMed:24844575, CC ECO:0000269|PubMed:25310980, ECO:0000269|PubMed:27906160, CC ECO:0000269|PubMed:27906161, ECO:0000269|PubMed:27934701, CC ECO:0000269|PubMed:353728, ECO:0000269|PubMed:354687, CC ECO:0000269|PubMed:6159586, ECO:0000269|PubMed:7038683, CC ECO:0000269|PubMed:8925931}. CC -!- DOMAIN: The basic N-terminus is not necessary for binding to 5S rRNA. CC It is however required for cooperative binding of L5 and L18 to 5S rRNA CC as well as for binding of the 5S rRNA/L5/L18 complex to the 23S rRNA. CC {ECO:0000269|PubMed:353728}. CC -!- PTM: The protein has been shown to contain a phosphoserine, which was CC required for the protein to bind to 5S rRNA (PubMed:10529214). However, CC the presence of this phosphoserine is controversial, and it has not CC been seen by mass spectrometry. {ECO:0000269|PubMed:10529214}. CC -!- MASS SPECTROMETRY: Mass=12769.8; Method=MALDI; CC Evidence={ECO:0000269|PubMed:10094780}; CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL18 family. CC {ECO:0000305}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; X01563; CAA25721.1; -; Genomic_DNA. DR EMBL; U18997; AAA58101.1; -; Genomic_DNA. DR EMBL; U00096; AAC76329.1; -; Genomic_DNA. DR EMBL; AP009048; BAE77987.1; -; Genomic_DNA. DR PIR; A02803; R5EC18. DR RefSeq; NP_417763.1; NC_000913.3. DR RefSeq; WP_000358960.1; NZ_CP009789.1. DR PDB; 10QM; EM; 2.49 A; W=1-117. DR PDB; 11BQ; EM; 3.00 A; n=1-117. DR PDB; 11DG; EM; 3.00 A; n=1-117. DR PDB; 11EL; EM; 3.20 A; n=1-117. DR PDB; 11FV; EM; 2.90 A; W=1-117. DR PDB; 11GG; EM; 3.02 A; W=1-117. DR PDB; 1ML5; EM; 14.00 A; q=3-115. DR PDB; 28UH; EM; 2.06 A; n=1-117. DR PDB; 28UI; EM; 2.10 A; n=1-117. DR PDB; 28UJ; EM; 2.16 A; n=1-117. DR PDB; 28UK; EM; 2.24 A; n=1-117. DR PDB; 28UL; EM; 2.50 A; n=1-117. DR PDB; 28UM; EM; 2.15 A; n=1-117. DR PDB; 28UN; EM; 2.48 A; n=1-117. DR PDB; 2J28; EM; 8.00 A; O=1-117. DR PDB; 2RDO; EM; 9.10 A; O=1-117. DR PDB; 30QZ; EM; 2.23 A; n=1-117. DR PDB; 30RA; EM; 2.78 A; n=1-117. DR PDB; 30RB; EM; 2.92 A; n=1-117. DR PDB; 3BBX; EM; 10.00 A; O=1-117. DR PDB; 3J5L; EM; 6.60 A; O=2-117. DR PDB; 3J7Z; EM; 3.90 A; O=1-117. DR PDB; 3J8G; EM; 5.00 A; O=1-117. DR PDB; 3J9Y; EM; 3.90 A; O=1-117. DR PDB; 3J9Z; EM; 3.60 A; LK=1-117. DR PDB; 3JA1; EM; 3.60 A; LQ=1-117. DR PDB; 3JBU; EM; 3.64 A; o=1-117. DR PDB; 3JBV; EM; 3.32 A; o=1-117. DR PDB; 3JCD; EM; 3.70 A; O=1-117. DR PDB; 3JCE; EM; 3.20 A; O=1-117. DR PDB; 3JCJ; EM; 3.70 A; N=1-117. DR PDB; 3JCN; EM; 4.60 A; O=1-117. DR PDB; 4CSU; EM; 5.50 A; O=2-117. DR PDB; 4U1U; X-ray; 2.95 A; BO/DO=2-117. DR PDB; 4U1V; X-ray; 3.00 A; BO/DO=2-117. DR PDB; 4U20; X-ray; 2.90 A; BO/DO=2-117. DR PDB; 4U24; X-ray; 2.90 A; BO/DO=2-117. DR PDB; 4U25; X-ray; 2.90 A; BO/DO=2-117. DR PDB; 4U26; X-ray; 2.80 A; BO/DO=2-117. DR PDB; 4U27; X-ray; 2.80 A; BO/DO=2-117. DR PDB; 4UY8; EM; 3.80 A; O=2-117. DR PDB; 4V47; EM; 12.30 A; AM=1-117. DR PDB; 4V48; EM; 11.50 A; AM=1-117. DR PDB; 4V4H; X-ray; 3.46 A; BO/DO=1-117. DR PDB; 4V4Q; X-ray; 3.46 A; BO/DO=1-117. DR PDB; 4V4V; EM; 15.00 A; BM=3-115. DR PDB; 4V4W; EM; 15.00 A; BM=3-115. DR PDB; 4V50; X-ray; 3.22 A; BO/DO=1-117. DR PDB; 4V52; X-ray; 3.21 A; BO/DO=1-117. DR PDB; 4V53; X-ray; 3.54 A; BO/DO=1-117. DR PDB; 4V54; X-ray; 3.30 A; BO/DO=1-117. DR PDB; 4V55; X-ray; 4.00 A; BO/DO=1-117. DR PDB; 4V56; X-ray; 3.93 A; BO/DO=1-117. DR PDB; 4V57; X-ray; 3.50 A; BO/DO=1-117. DR PDB; 4V5B; X-ray; 3.74 A; AO/CO=1-117. DR PDB; 4V5H; EM; 5.80 A; BO=2-117. DR PDB; 4V5Y; X-ray; 4.45 A; BO/DO=1-117. DR PDB; 4V64; X-ray; 3.50 A; BO/DO=1-117. DR PDB; 4V65; EM; 9.00 A; BH=1-117. DR PDB; 4V66; EM; 9.00 A; BH=1-117. DR PDB; 4V69; EM; 6.70 A; BO=2-117. DR PDB; 4V6C; X-ray; 3.19 A; BO/DO=1-117. DR PDB; 4V6D; X-ray; 3.81 A; BO/DO=1-117. DR PDB; 4V6E; X-ray; 3.71 A; BO/DO=1-117. DR PDB; 4V6K; EM; 8.25 A; AP=1-117. DR PDB; 4V6L; EM; 13.20 A; BP=1-117. DR PDB; 4V6M; EM; 7.10 A; BO=1-117. DR PDB; 4V6N; EM; 12.10 A; AQ=1-117. DR PDB; 4V6O; EM; 14.70 A; BQ=1-117. DR PDB; 4V6P; EM; 13.50 A; BQ=1-117. DR PDB; 4V6Q; EM; 11.50 A; BQ=1-117. DR PDB; 4V6R; EM; 11.50 A; BQ=1-117. DR PDB; 4V6S; EM; 13.10 A; AQ=1-117. DR PDB; 4V6T; EM; 8.30 A; BO=2-117. DR PDB; 4V6V; EM; 9.80 A; BS=1-117. DR PDB; 4V6Y; EM; 12.00 A; BO=1-117. DR PDB; 4V6Z; EM; 12.00 A; BO=1-117. DR PDB; 4V70; EM; 17.00 A; BO=1-117. DR PDB; 4V71; EM; 20.00 A; BO=1-117. DR PDB; 4V72; EM; 13.00 A; BO=1-117. DR PDB; 4V73; EM; 15.00 A; BO=1-117. DR PDB; 4V74; EM; 17.00 A; BO=1-117. DR PDB; 4V75; EM; 12.00 A; BO=1-117. DR PDB; 4V76; EM; 17.00 A; BO=1-117. DR PDB; 4V77; EM; 17.00 A; BO=1-117. DR PDB; 4V78; EM; 20.00 A; BO=1-117. DR PDB; 4V79; EM; 15.00 A; BO=1-117. DR PDB; 4V7A; EM; 9.00 A; BO=1-117. DR PDB; 4V7B; EM; 6.80 A; BO=1-117. DR PDB; 4V7C; EM; 7.60 A; BQ=1-117. DR PDB; 4V7D; EM; 7.60 A; AR=1-117. DR PDB; 4V7I; EM; 9.60 A; AO=1-117. DR PDB; 4V7S; X-ray; 3.25 A; BO/DO=2-117. DR PDB; 4V7T; X-ray; 3.19 A; BO/DO=2-117. DR PDB; 4V7U; X-ray; 3.10 A; BO/DO=2-117. DR PDB; 4V7V; X-ray; 3.29 A; BO/DO=2-117. DR PDB; 4V85; X-ray; 3.20 A; BS=1-117. DR PDB; 4V89; X-ray; 3.70 A; BS=1-117. DR PDB; 4V9C; X-ray; 3.30 A; BO/DO=1-117. DR PDB; 4V9D; X-ray; 3.00 A; CO/DO=2-117. DR PDB; 4V9O; X-ray; 2.90 A; AO/CO/EO/GO=1-117. DR PDB; 4V9P; X-ray; 2.90 A; AO/CO/EO/GO=1-117. DR PDB; 4WF1; X-ray; 3.09 A; BO/DO=2-117. DR PDB; 4WOI; X-ray; 3.00 A; BO/CO=1-117. DR PDB; 4WWW; X-ray; 3.10 A; RO/YO=2-117. DR PDB; 4YBB; X-ray; 2.10 A; CP/DP=1-117. DR PDB; 5ADY; EM; 4.50 A; O=1-117. DR PDB; 5AFI; EM; 2.90 A; O=1-117. DR PDB; 5AKA; EM; 5.70 A; O=1-117. DR PDB; 5GAD; EM; 3.70 A; P=1-117. DR PDB; 5GAE; EM; 3.33 A; P=1-117. DR PDB; 5GAF; EM; 4.30 A; P=1-117. DR PDB; 5GAG; EM; 3.80 A; P=1-117. DR PDB; 5GAH; EM; 3.80 A; P=1-117. DR PDB; 5H5U; EM; 3.00 A; P=1-117. DR PDB; 5IQR; EM; 3.00 A; O=1-117. DR PDB; 5IT8; X-ray; 3.12 A; CP/DP=1-117. DR PDB; 5J5B; X-ray; 2.80 A; CP/DP=1-117. DR PDB; 5J7L; X-ray; 3.00 A; CP/DP=1-117. DR PDB; 5J88; X-ray; 3.32 A; CP/DP=1-117. DR PDB; 5J8A; X-ray; 3.10 A; CP/DP=1-117. DR PDB; 5J91; X-ray; 2.96 A; CP/DP=1-117. DR PDB; 5JC9; X-ray; 3.03 A; CP/DP=1-117. DR PDB; 5JTE; EM; 3.60 A; BO=1-117. DR PDB; 5JU8; EM; 3.60 A; BO=1-117. DR PDB; 5KCR; EM; 3.60 A; 1S=1-117. DR PDB; 5KCS; EM; 3.90 A; 1S=1-117. DR PDB; 5KPS; EM; 3.90 A; O=1-117. DR PDB; 5KPV; EM; 4.10 A; N=1-117. DR PDB; 5KPW; EM; 3.90 A; N=1-117. DR PDB; 5KPX; EM; 3.90 A; N=1-117. DR PDB; 5L3P; EM; 3.70 A; S=1-117. DR PDB; 5LZA; EM; 3.60 A; O=2-117. DR PDB; 5LZB; EM; 5.30 A; O=2-117. DR PDB; 5LZC; EM; 4.80 A; O=2-117. DR PDB; 5LZD; EM; 3.40 A; O=2-117. DR PDB; 5LZE; EM; 3.50 A; O=2-117. DR PDB; 5LZF; EM; 4.60 A; O=2-117. DR PDB; 5MDV; EM; 2.97 A; O=1-117. DR PDB; 5MDW; EM; 3.06 A; O=1-117. DR PDB; 5MDY; EM; 3.35 A; O=1-117. DR PDB; 5MDZ; EM; 3.10 A; O=1-117. DR PDB; 5MGP; EM; 3.10 A; O=2-117. DR PDB; 5NCO; EM; 4.80 A; P=1-117. DR PDB; 5NP6; EM; 3.60 A; m=2-117. DR PDB; 5NWY; EM; 2.93 A; b=1-117. DR PDB; 5O2R; EM; 3.40 A; O=2-117. DR PDB; 5U4I; EM; 3.50 A; P=1-117. DR PDB; 5U9F; EM; 3.20 A; 17=1-117. DR PDB; 5U9G; EM; 3.20 A; 17=1-117. DR PDB; 5UYK; EM; 3.90 A; 17=2-117. DR PDB; 5UYL; EM; 3.60 A; 17=2-117. DR PDB; 5UYM; EM; 3.20 A; 17=2-117. DR PDB; 5UYN; EM; 4.00 A; 17=2-117. DR PDB; 5UYP; EM; 3.90 A; 17=2-117. DR PDB; 5UYQ; EM; 3.80 A; 17=2-117. DR PDB; 5WDT; EM; 3.00 A; O=2-117. DR PDB; 5WE4; EM; 3.10 A; O=2-117. DR PDB; 5WE6; EM; 3.40 A; O=2-117. DR PDB; 5WF0; EM; 3.60 A; O=2-117. DR PDB; 5WFK; EM; 3.40 A; O=2-117. DR PDB; 5WFS; EM; 3.00 A; O=2-117. DR PDB; 6BU8; EM; 3.50 A; 17=2-117. DR PDB; 6BY1; X-ray; 3.94 A; CO/DO=2-117. DR PDB; 6C4I; EM; 3.24 A; P=1-117. DR PDB; 6DNC; EM; 3.70 A; S=1-117. DR PDB; 6ENF; EM; 3.20 A; O=2-117. DR PDB; 6ENJ; EM; 3.70 A; O=2-117. DR PDB; 6ENU; EM; 3.10 A; O=2-117. DR PDB; 6GBZ; EM; 3.80 A; O=2-117. DR PDB; 6GC0; EM; 3.80 A; O=2-117. DR PDB; 6GC4; EM; 4.30 A; O=2-117. DR PDB; 6GC8; EM; 3.80 A; O=2-117. DR PDB; 6GWT; EM; 3.80 A; O=2-117. DR PDB; 6GXM; EM; 3.80 A; O=2-117. DR PDB; 6GXN; EM; 3.90 A; O=2-117. DR PDB; 6GXO; EM; 3.90 A; O=2-117. DR PDB; 6GXP; EM; 4.40 A; O=2-117. DR PDB; 6H4N; EM; 3.00 A; O=2-117. DR PDB; 6H58; EM; 7.90 A; O/OO=2-117. DR PDB; 6HRM; EM; 2.96 A; O=2-117. DR PDB; 6I0Y; EM; 3.20 A; O=2-117. DR PDB; 6I7V; X-ray; 2.90 A; CP/DP=1-117. DR PDB; 6O9J; EM; 3.90 A; O=1-117. DR PDB; 6O9K; EM; 4.00 A; O=2-117. DR PDB; 6OFX; EM; 3.30 A; o=2-117. DR PDB; 6OG7; EM; 3.30 A; o=2-117. DR PDB; 6OGF; EM; 3.90 A; o=1-117. DR PDB; 6OGG; EM; 4.20 A; o=1-117. DR PDB; 6OGI; EM; 3.40 A; o=1-117. DR PDB; 6OM6; EM; 3.10 A; O=1-117. DR PDB; 6ORE; EM; 2.90 A; O=2-117. DR PDB; 6ORL; EM; 3.50 A; O=2-117. DR PDB; 6OSK; EM; 3.60 A; O=2-117. DR PDB; 6OSQ; EM; 3.50 A; O=2-117. DR PDB; 6OST; EM; 4.20 A; O=2-117. DR PDB; 6OT3; EM; 3.90 A; O=2-117. DR PDB; 6OUO; EM; 3.70 A; O=2-117. DR PDB; 6PJ6; EM; 2.20 A; W=1-117. DR PDB; 6Q97; EM; 3.90 A; O=3-117. DR PDB; 6Q98; EM; 4.30 A; O=1-117. DR PDB; 6Q9A; EM; 3.70 A; O=3-117. DR PDB; 6QDW; EM; 2.83 A; o=1-117. DR PDB; 6QUL; EM; 3.00 A; P=1-117. DR PDB; 6S0K; EM; 3.10 A; P=1-117. DR PDB; 6SZS; EM; 3.06 A; O=1-117. DR PDB; 6TBV; EM; 2.70 A; L181=1-117. DR PDB; 6TC3; EM; 2.70 A; L181=1-117. DR PDB; 6U48; EM; 2.87 A; CP=2-117. DR PDB; 6VU3; EM; 3.70 A; x=2-117. DR PDB; 6VWL; EM; 3.10 A; M=1-117. DR PDB; 6VWM; EM; 3.40 A; M=1-117. DR PDB; 6VWN; EM; 3.40 A; M=1-117. DR PDB; 6VYQ; EM; 3.70 A; x=1-117. DR PDB; 6VYR; EM; 3.80 A; x=1-117. DR PDB; 6VYS; EM; 3.70 A; x=1-117. DR PDB; 6VYT; EM; 14.00 A; x=1-117. DR PDB; 6VYU; EM; 7.00 A; x=1-117. DR PDB; 6VYW; EM; 7.00 A; x=1-117. DR PDB; 6VYX; EM; 9.90 A; x=1-117. DR PDB; 6VYY; EM; 9.90 A; x=1-117. DR PDB; 6VYZ; EM; 9.90 A; x=1-117. DR PDB; 6VZ2; EM; 10.00 A; x=1-117. DR PDB; 6VZ3; EM; 8.90 A; x=2-117. DR PDB; 6VZ5; EM; 8.90 A; x=1-117. DR PDB; 6VZ7; EM; 7.00 A; x=2-117. DR PDB; 6VZJ; EM; 4.10 A; x=2-117. DR PDB; 6WD0; EM; 3.00 A; o=2-117. DR PDB; 6WD1; EM; 3.30 A; o=2-117. DR PDB; 6WD2; EM; 3.60 A; o=2-117. DR PDB; 6WD3; EM; 3.60 A; o=2-117. DR PDB; 6WD4; EM; 3.70 A; o=2-117. DR PDB; 6WD5; EM; 3.60 A; o=2-117. DR PDB; 6WD6; EM; 3.70 A; o=2-117. DR PDB; 6WD7; EM; 3.90 A; o=2-117. DR PDB; 6WD8; EM; 3.70 A; o=2-117. DR PDB; 6WD9; EM; 3.70 A; o=2-117. DR PDB; 6WDA; EM; 3.80 A; o=2-117. DR PDB; 6WDB; EM; 4.00 A; o=2-117. DR PDB; 6WDC; EM; 4.20 A; o=2-117. DR PDB; 6WDD; EM; 3.20 A; o=2-117. DR PDB; 6WDE; EM; 3.00 A; o=2-117. DR PDB; 6WDF; EM; 3.30 A; o=2-117. DR PDB; 6WDG; EM; 3.30 A; o=2-117. DR PDB; 6WDH; EM; 4.30 A; o=2-117. DR PDB; 6WDI; EM; 4.00 A; o=2-117. DR PDB; 6WDJ; EM; 3.70 A; o=2-117. DR PDB; 6WDK; EM; 3.60 A; o=2-117. DR PDB; 6WDL; EM; 3.70 A; o=2-117. DR PDB; 6WDM; EM; 3.60 A; o=2-117. DR PDB; 6WNT; EM; 3.10 A; o=2-117. DR PDB; 6WNV; EM; 3.50 A; o=2-117. DR PDB; 6WNW; EM; 3.20 A; o=2-117. DR PDB; 6X6T; EM; 3.20 A; x=1-117. DR PDB; 6X7F; EM; 3.50 A; x=1-117. DR PDB; 6X7K; EM; 3.10 A; x=1-117. DR PDB; 6X9Q; EM; 4.80 A; x=1-117. DR PDB; 6XDQ; EM; 3.70 A; x=1-117. DR PDB; 6XDR; EM; 4.70 A; x=1-117. DR PDB; 6XGF; EM; 5.00 A; x=1-117. DR PDB; 6XII; EM; 7.00 A; x=1-117. DR PDB; 6XIJ; EM; 8.00 A; x=1-117. DR PDB; 6XZ7; EM; 2.10 A; O=1-117. DR PDB; 6XZA; EM; 2.66 A; O2=1-117. DR PDB; 6XZB; EM; 2.54 A; O2=1-117. DR PDB; 6Y69; EM; 2.86 A; O=2-117. DR PDB; 6YSR; EM; 3.10 A; O=1-117. DR PDB; 6YSS; EM; 2.60 A; O=1-117. DR PDB; 6YST; EM; 3.20 A; O=1-117. DR PDB; 6YSU; EM; 3.70 A; O=1-117. DR PDB; 6ZTJ; EM; 3.40 A; BP=1-117. DR PDB; 6ZTL; EM; 3.50 A; BP=1-117. DR PDB; 6ZTM; EM; 3.30 A; BP=1-117. DR PDB; 6ZTN; EM; 3.90 A; BP=1-117. DR PDB; 6ZTO; EM; 3.00 A; BP=1-117. DR PDB; 6ZTP; EM; 3.00 A; BP=1-117. DR PDB; 6ZU1; EM; 3.00 A; BP=1-117. DR PDB; 7ABZ; EM; 3.21 A; O=2-117. DR PDB; 7AC7; EM; 3.08 A; O=3-117. DR PDB; 7ACJ; EM; 3.20 A; O=2-117. DR PDB; 7ACR; EM; 3.44 A; O=2-117. DR PDB; 7B5K; EM; 2.90 A; O=1-117. DR PDB; 7BL2; EM; 3.70 A; O=1-117. DR PDB; 7BL3; EM; 3.50 A; O=1-117. DR PDB; 7BL4; EM; 2.40 A; O=1-117. DR PDB; 7BL5; EM; 3.30 A; O=1-117. DR PDB; 7BL6; EM; 4.00 A; O=1-117. DR PDB; 7BV8; EM; 3.14 A; P=1-117. DR PDB; 7D6Z; EM; 3.40 A; O=1-117. DR PDB; 7D80; EM; 4.10 A; n=1-117. DR PDB; 7JSS; EM; 3.70 A; o=2-117. DR PDB; 7JSW; EM; 3.80 A; o=2-117. DR PDB; 7JSZ; EM; 3.70 A; o=2-117. DR PDB; 7JT1; EM; 3.30 A; o=2-117. DR PDB; 7JT2; EM; 3.50 A; o=2-117. DR PDB; 7JT3; EM; 3.70 A; o=2-117. DR PDB; 7K00; EM; 1.98 A; n=1-117. DR PDB; 7K50; EM; 3.40 A; o=2-117. DR PDB; 7K51; EM; 3.50 A; o=2-117. DR PDB; 7K52; EM; 3.40 A; o=2-117. DR PDB; 7K53; EM; 3.20 A; o=2-117. DR PDB; 7K54; EM; 3.20 A; o=2-117. DR PDB; 7K55; EM; 3.30 A; o=2-117. DR PDB; 7LV0; EM; 3.20 A; o=2-117. DR PDB; 7LVK; EM; 2.20 A; W=1-117. DR PDB; 7M5D; EM; 2.80 A; O=2-117. DR PDB; 7N1P; EM; 2.33 A; LR=1-117. DR PDB; 7N2C; EM; 2.72 A; LR=1-117. DR PDB; 7N2U; EM; 2.53 A; LR=1-117. DR PDB; 7N2V; EM; 2.54 A; LR=1-117. DR PDB; 7N30; EM; 2.66 A; LR=1-117. DR PDB; 7N31; EM; 2.69 A; LR=1-117. DR PDB; 7NBU; EM; 3.11 A; n=2-117. DR PDB; 7NWT; EM; 2.66 A; O=1-117. DR PDB; 7O19; EM; 2.90 A; BO=1-117. DR PDB; 7O1A; EM; 2.40 A; BO=1-117. DR PDB; 7O1C; EM; 2.60 A; BO=1-117. DR PDB; 7OIZ; EM; 2.90 A; n=1-117. DR PDB; 7OJ0; EM; 3.50 A; n=1-117. DR PDB; 7P3K; EM; 2.90 A; n=1-117. DR PDB; 7PJS; EM; 2.35 A; O=1-117. DR PDB; 7PJT; EM; 6.00 A; O=1-117. DR PDB; 7PJU; EM; 9.50 A; O=1-117. DR PDB; 7PJV; EM; 3.10 A; O=1-117. DR PDB; 7PJW; EM; 4.00 A; O=1-117. DR PDB; 7PJX; EM; 6.50 A; O=1-117. DR PDB; 7PJY; EM; 3.10 A; O=1-117. DR PDB; 7PJZ; EM; 6.00 A; O=1-117. DR PDB; 7Q4K; EM; 3.00 A; BO=1-117. DR PDB; 7QG8; EM; 3.97 A; b=1-117. DR PDB; 7QGH; EM; 4.48 A; b=1-117. DR PDB; 7QGN; EM; 3.37 A; b=1-117. DR PDB; 7QGR; EM; 5.70 A; b=1-117. DR PDB; 7QQ3; EM; 2.10 A; W=1-117. DR PDB; 7S1G; EM; 2.48 A; W=1-117. DR PDB; 7S1H; EM; 2.35 A; W=1-117. DR PDB; 7S1I; EM; 2.48 A; W=1-117. DR PDB; 7S1J; EM; 2.47 A; W=1-117. DR PDB; 7S1K; EM; 2.42 A; W=1-117. DR PDB; 7SA4; EM; 2.55 A; O=1-117. DR PDB; 7SS9; EM; 3.90 A; o=2-117. DR PDB; 7SSD; EM; 3.30 A; o=2-117. DR PDB; 7SSL; EM; 3.80 A; o=2-117. DR PDB; 7SSN; EM; 3.20 A; o=2-117. DR PDB; 7SSO; EM; 3.20 A; o=2-117. DR PDB; 7SSW; EM; 3.80 A; o=2-117. DR PDB; 7ST2; EM; 2.90 A; o=2-117. DR PDB; 7ST6; EM; 3.00 A; o=2-117. DR PDB; 7ST7; EM; 3.20 A; o=2-117. DR PDB; 7TOS; EM; 2.90 A; L18=2-117. DR PDB; 7UG7; EM; 2.58 A; LR=1-117. DR PDB; 7UPH; EM; 4.18 A; n=2-117. DR PDB; 7Y7C; EM; 2.51 A; n=1-117. DR PDB; 7Y7D; EM; 2.58 A; n=1-117. DR PDB; 7Y7E; EM; 2.41 A; n=1-117. DR PDB; 7Y7F; EM; 2.43 A; n=1-117. DR PDB; 7Y7G; EM; 2.34 A; n=1-117. DR PDB; 7Y7H; EM; 2.51 A; n=1-117. DR PDB; 7YLA; EM; 2.52 A; W=2-117. DR PDB; 7Z20; EM; 2.29 A; o=1-117. DR PDB; 7ZOD; EM; 2.56 A; o=1-117. DR PDB; 7ZP8; EM; 2.20 A; o=1-117. DR PDB; 7ZQ5; EM; 2.70 A; o=1-117. DR PDB; 7ZQ6; EM; 2.75 A; o=1-117. DR PDB; 7ZTA; EM; 2.70 A; L181=1-117. DR PDB; 8A3L; EM; 3.42 A; n=1-117. DR PDB; 8AKN; EM; 2.30 A; n=1-117. DR PDB; 8AM9; EM; 2.80 A; n=1-117. DR PDB; 8ANA; EM; 2.10 A; n=1-117. DR PDB; 8AP4; EM; 3.00 A; n=1-117. DR PDB; 8AYE; EM; 1.96 A; n=1-117. DR PDB; 8B0X; EM; 1.55 A; n=1-117. DR PDB; 8B7Y; EM; 3.00 A; W=1-117. DR PDB; 8BF7; EM; 2.33 A; L=1-117. DR PDB; 8BGE; EM; 2.11 A; L=1-117. DR PDB; 8BGH; EM; 2.88 A; L=1-117. DR PDB; 8BH4; EM; 2.62 A; L=1-117. DR PDB; 8BHJ; EM; 2.81 A; L=1-117. DR PDB; 8BHL; EM; 2.21 A; L=1-117. DR PDB; 8BHN; EM; 2.85 A; L=1-117. DR PDB; 8BHP; EM; 2.37 A; L=1-117. DR PDB; 8BIL; EM; 2.04 A; L=1-117. DR PDB; 8BIM; EM; 2.04 A; L=1-117. DR PDB; 8C8X; EM; 3.93 A; O=1-117. DR PDB; 8C8Y; EM; 3.03 A; O=1-117. DR PDB; 8C8Z; EM; 3.12 A; O=1-117. DR PDB; 8C90; EM; 3.15 A; O=1-117. DR PDB; 8C94; EM; 3.80 A; O=1-117. DR PDB; 8C95; EM; 4.92 A; O=1-117. DR PDB; 8CEU; EM; 1.83 A; n=1-117. DR PDB; 8CGD; EM; 1.98 A; n=1-117. DR PDB; 8CGV; EM; 1.66 A; n=1-117. DR PDB; 8EIU; EM; 2.24 A; n=1-117. DR PDB; 8EKC; EM; 2.70 A; Q=1-117. DR PDB; 8EMM; EM; 2.10 A; n=1-117. DR PDB; 8FIZ; EM; 3.80 A; BH=1-117. DR PDB; 8FTO; EM; 1.85 A; n=1-117. DR PDB; 8FZD; EM; 3.10 A; Q=1-117. DR PDB; 8FZE; EM; 3.00 A; Q=1-117. DR PDB; 8FZF; EM; 3.20 A; Q=1-117. DR PDB; 8FZG; EM; 3.10 A; Q=1-117. DR PDB; 8FZH; EM; 2.90 A; Q=1-117. DR PDB; 8FZI; EM; 3.10 A; Q=1-117. DR PDB; 8FZJ; EM; 3.00 A; Q=1-117. DR PDB; 8G2U; EM; 3.00 A; O=2-117. DR PDB; 8G31; EM; 3.20 A; O=2-117. DR PDB; 8G34; EM; 3.20 A; O=2-117. DR PDB; 8G38; EM; 3.20 A; O=2-117. DR PDB; 8G6W; EM; 2.02 A; n=1-117. DR PDB; 8G6X; EM; 2.31 A; n=1-117. DR PDB; 8G6Y; EM; 2.09 A; n=1-117. DR PDB; 8G7P; EM; 2.90 A; Q=1-117. DR PDB; 8G7Q; EM; 3.10 A; Q=1-117. DR PDB; 8G7R; EM; 2.80 A; Q=1-117. DR PDB; 8G7S; EM; 3.10 A; Q=1-117. DR PDB; 8HSP; EM; 2.32 A; n=1-117. DR PDB; 8HTZ; EM; 2.40 A; n=1-117. DR PDB; 8HU1; EM; 2.69 A; n=1-117. DR PDB; 8IFB; EM; 2.43 A; n=1-117. DR PDB; 8IFC; EM; 2.90 A; n=1-117. DR PDB; 8J1Z; EM; 2.60 A; n=1-117. DR PDB; 8P16; EM; 2.77 A; O=1-117. DR PDB; 8P17; EM; 2.78 A; O=1-117. DR PDB; 8P18; EM; 2.77 A; O=1-117. DR PDB; 8PEG; EM; 3.30 A; r=1-117. DR PDB; 8PHJ; EM; 3.67 A; n=1-117. DR PDB; 8PKL; EM; 3.09 A; r=1-117. DR PDB; 8PVA; EM; 4.50 A; n=1-117. DR PDB; 8QBT; EM; 2.20 A; O=1-117. DR PDB; 8QK7; EM; 2.77 A; O=1-117. DR PDB; 8QOA; EM; 2.00 A; n=1-117. DR PDB; 8R3V; EM; 3.28 A; r2=1-117. DR PDB; 8R6C; EM; 2.20 A; n=1-117. DR PDB; 8R8M; EM; 2.40 A; n=1-117. DR PDB; 8RCL; EM; 3.49 A; r2=1-117. DR PDB; 8RCM; EM; 3.59 A; r2=1-117. DR PDB; 8RCS; EM; 4.46 A; r2=1-117. DR PDB; 8RCT; EM; 5.32 A; r2=1-117. DR PDB; 8RPY; EM; 2.64 A; O=2-117. DR PDB; 8RPZ; EM; 2.44 A; O=2-117. DR PDB; 8RQ0; EM; 2.44 A; O=2-117. DR PDB; 8RQ2; EM; 2.44 A; O=2-117. DR PDB; 8SYL; EM; 2.90 A; Q=1-117. DR PDB; 8T5D; EM; 3.20 A; O=2-117. DR PDB; 8T5H; EM; 3.30 A; O=2-117. DR PDB; 8URM; EM; 3.00 A; O=1-117. DR PDB; 8UTJ; EM; 3.50 A; O=1-117. DR PDB; 8UX8; EM; 3.60 A; O=1-117. DR PDB; 8UXB; EM; 2.90 A; O=1-117. DR PDB; 8UZ3; EM; 3.20 A; O=1-117. DR PDB; 8UZG; EM; 3.70 A; O=1-117. DR PDB; 8V03; EM; 4.00 A; O=1-117. DR PDB; 8VKV; EM; 3.60 A; x=1-117. DR PDB; 8VL1; EM; 5.30 A; x=1-117. DR PDB; 8VOO; EM; 3.40 A; x=1-117. DR PDB; 8VOP; EM; 6.00 A; x=1-117. DR PDB; 8VOQ; EM; 9.30 A; x=1-117. DR PDB; 8VOR; EM; 3.60 A; x=1-117. DR PDB; 8VOS; EM; 4.60 A; x=1-117. DR PDB; 8VS9; EM; 3.90 A; L18=1-117. DR PDB; 8VSA; EM; 3.70 A; L18=1-117. DR PDB; 8W51; EM; 2.40 A; P=1-117. DR PDB; 8Y5K; EM; 6.90 A; o=1-117. DR PDB; 8Y5L; EM; 3.70 A; o=1-117. DR PDB; 8Y5M; EM; 4.50 A; o=1-117. DR PDB; 8Y5N; EM; 4.50 A; o=1-117. DR PDB; 8Y5O; EM; 4.20 A; o=1-117. DR PDB; 8Y5P; EM; 6.50 A; o=1-117. DR PDB; 8Y5Q; EM; 3.90 A; o=1-117. DR PDB; 8Y5R; EM; 4.50 A; o=1-117. DR PDB; 8Y5S; EM; 4.50 A; o=1-117. DR PDB; 8Y5T; EM; 4.40 A; o=1-117. DR PDB; 8YDE; EM; 5.00 A; o=1-117. DR PDB; 8YDF; EM; 4.60 A; o=1-117. DR PDB; 8YDG; EM; 5.10 A; o=1-117. DR PDB; 8YDH; EM; 4.55 A; o=1-117. DR PDB; 8YDI; EM; 4.60 A; o=1-117. DR PDB; 8YDJ; EM; 5.10 A; o=1-117. DR PDB; 8YUO; EM; 2.25 A; n=1-117. DR PDB; 8YUP; EM; 2.39 A; n=1-117. DR PDB; 8YUQ; EM; 2.41 A; n=1-117. DR PDB; 8YUR; EM; 2.47 A; n=1-117. DR PDB; 8YUS; EM; 2.43 A; n=1-117. DR PDB; 8ZEJ; EM; 2.69 A; p=1-117. DR PDB; 8ZFF; EM; 2.59 A; n=1-117. DR PDB; 8ZFG; EM; 2.68 A; n=1-117. DR PDB; 8ZFI; EM; 2.90 A; p=1-117. DR PDB; 8ZTU; EM; 2.90 A; n=1-117. DR PDB; 8ZTV; EM; 2.90 A; n=1-117. DR PDB; 9B4Z; EM; 2.20 A; BO=1-117. DR PDB; 9B50; EM; 2.70 A; BO=1-117. DR PDB; 9B51; EM; 2.40 A; BO=1-117. DR PDB; 9D89; EM; 1.95 A; n=2-117. DR PDB; 9FBV; EM; 2.40 A; n=1-117. DR PDB; 9GFT; EM; 3.10 A; Aj/b=1-117. DR PDB; 9GGR; EM; 3.20 A; Aj/b=1-117. DR PDB; 9GHA; EM; 2.24 A; n=1-117. DR PDB; 9GHB; EM; 2.21 A; n=1-117. DR PDB; 9GHC; EM; 2.79 A; n=1-117. DR PDB; 9GHD; EM; 2.41 A; n=1-117. DR PDB; 9GHE; EM; 1.87 A; n=1-117. DR PDB; 9GHF; EM; 2.40 A; n=1-117. DR PDB; 9GR1; EM; 3.17 A; n=1-117. DR PDB; 9GXX; EM; 2.61 A; n=1-117. DR PDB; 9H0L; EM; 2.49 A; n=1-117. DR PDB; 9H3P; EM; 7.06 A; O=2-117. DR PDB; 9H3Q; EM; 4.02 A; O=2-117. DR PDB; 9H3R; EM; 4.12 A; O=2-117. DR PDB; 9H3S; EM; 4.16 A; O=2-117. DR PDB; 9H3V; EM; 3.55 A; O=2-117. DR PDB; 9H3W; EM; 5.38 A; O=2-117. DR PDB; 9H3X; EM; 4.12 A; O=2-117. DR PDB; 9H3Y; EM; 3.09 A; O=2-117. DR PDB; 9H3Z; EM; 2.98 A; O=2-117. DR PDB; 9HA4; EM; 4.26 A; O=2-117. DR PDB; 9HA6; EM; 3.08 A; O=2-117. DR PDB; 9HA7; EM; 4.37 A; O=2-117. DR PDB; 9HUQ; EM; 2.49 A; o=1-117. DR PDB; 9HUS; EM; 2.40 A; o=1-117. DR PDB; 9HY6; EM; 2.60 A; o=1-117. DR PDB; 9HYM; EM; 2.20 A; o=1-117. DR PDB; 9I3L; EM; 3.10 A; o=1-117. DR PDB; 9IOT; EM; 2.70 A; Q=1-117. DR PDB; 9JMK; EM; 4.00 A; O=1-117. DR PDB; 9JPM; EM; 2.43 A; n=1-117. DR PDB; 9JPO; EM; 3.18 A; n=1-117. DR PDB; 9JPP; EM; 2.26 A; n=1-117. DR PDB; 9JQ2; EM; 2.61 A; n=1-117. DR PDB; 9MKK; EM; 3.20 A; n=1-117. DR PDB; 9MOR; EM; 2.65 A; O=1-117. DR PDB; 9MQ4; EM; 2.78 A; O=1-117. DR PDB; 9N2B; EM; 2.20 A; LR=1-117. DR PDB; 9N2C; EM; 2.40 A; LR=1-117. DR PDB; 9NJF; EM; 3.40 A; 18=2-117. DR PDB; 9NJV; EM; 3.10 A; 18=2-117. DR PDB; 9NKL; EM; 3.30 A; 18=2-117. DR PDB; 9NL5; EM; 3.00 A; 18=2-117. DR PDB; 9NL6; EM; 3.20 A; 18=2-117. DR PDB; 9NL7; EM; 3.30 A; 18=2-117. DR PDB; 9NLB; EM; 3.20 A; 18=2-117. DR PDB; 9NLE; EM; 3.20 A; 18=2-117. DR PDB; 9NLF; EM; 3.20 A; 18=2-117. DR PDB; 9NLH; EM; 3.10 A; 18=2-117. DR PDB; 9NLJ; EM; 3.10 A; 18=2-117. DR PDB; 9NLQ; EM; 3.30 A; 18=2-117. DR PDB; 9NLS; EM; 3.30 A; 18=2-117. DR PDB; 9O2X; EM; 2.29 A; n=1-117. DR PDB; 9O2Y; EM; 2.14 A; n=1-117. DR PDB; 9PIH; EM; 2.40 A; n=1-117. DR PDB; 9PII; EM; 2.40 A; n=1-117. DR PDB; 9PIJ; EM; 2.20 A; n=1-117. DR PDB; 9Q87; EM; 1.55 A; n=1-117. DR PDB; 9QQQ; EM; 2.26 A; n=1-117. DR PDB; 9QSJ; EM; 2.62 A; n=1-117. DR PDB; 9R3A; EM; 2.86 A; n=1-117. DR PDB; 9RBF; EM; 2.44 A; n=1-117. DR PDB; 9RFW; EM; 2.40 A; n=1-117. DR PDB; 9RJA; EM; 2.45 A; n=1-117. DR PDB; 9RTU; EM; 3.00 A; O=1-117. DR PDB; 9RTV; EM; 3.60 A; O=1-117. DR PDB; 9SLG; EM; 2.16 A; n=1-117. DR PDB; 9SRO; EM; 2.60 A; n=1-117. DR PDB; 9SS4; EM; 2.70 A; BR=1-117. DR PDB; 9SS5; EM; 2.70 A; BR=1-117. DR PDB; 9SS6; EM; 2.60 A; BR=1-117. DR PDB; 9SYH; EM; 1.89 A; n=1-117. DR PDB; 9T0Y; EM; 1.87 A; n=1-117. DR PDB; 9T6M; EM; 1.87 A; n=1-117. DR PDB; 9TEW; EM; 2.90 A; n=1-117. DR PDB; 9TEX; EM; 2.54 A; n=1-117. DR PDB; 9TEZ; EM; 2.88 A; n=1-117. DR PDB; 9TMI; EM; 2.08 A; n=1-117. DR PDB; 9TNL; EM; 2.11 A; n=1-117. DR PDB; 9TQA; EM; 2.06 A; n=1-117. DR PDB; 9VVI; EM; 2.82 A; n=1-117. DR PDB; 9WNQ; EM; 2.59 A; p=1-117. DR PDB; 9WNR; EM; 2.76 A; p=1-117. DR PDB; 9XFK; EM; 2.98 A; W=2-117. DR PDB; 9XFL; EM; 3.16 A; W=2-117. DR PDB; 9XWO; EM; 2.89 A; n=1-117. DR PDB; 9Y79; EM; 3.20 A; x=1-117. DR PDB; 9ZTL; EM; 2.91 A; n=1-117. DR AlphaFoldDB; P0C018; -. DR EMDB; EMD-0076; -. DR EMDB; EMD-0080; -. DR EMDB; EMD-0081; -. DR EMDB; EMD-0082; -. DR EMDB; EMD-0083; -. DR EMDB; EMD-0137; -. DR EMDB; EMD-0139; -. DR EMDB; EMD-0261; -. DR EMDB; EMD-0322; -. DR EMDB; EMD-10073; -. DR EMDB; EMD-10353; -. DR EMDB; EMD-10453; -. DR EMDB; EMD-10458; -. DR EMDB; EMD-10655; -. DR EMDB; EMD-10656; -. DR EMDB; EMD-10657; -. DR EMDB; EMD-10705; -. DR EMDB; EMD-10905; -. DR EMDB; EMD-10906; -. DR EMDB; EMD-10907; -. DR EMDB; EMD-10908; -. DR EMDB; EMD-11418; -. DR EMDB; EMD-11419; -. DR EMDB; EMD-11420; -. DR EMDB; EMD-11421; -. DR EMDB; EMD-11422; -. DR EMDB; EMD-11423; -. DR EMDB; EMD-11426; -. DR EMDB; EMD-11710; -. DR EMDB; EMD-11713; -. DR EMDB; EMD-11717; -. DR EMDB; EMD-11718; -. DR EMDB; EMD-12035; -. DR EMDB; EMD-12215; -. DR EMDB; EMD-12216; -. DR EMDB; EMD-12217; -. DR EMDB; EMD-12218; -. DR EMDB; EMD-12219; -. DR EMDB; EMD-12261; -. DR EMDB; EMD-12635; -. DR EMDB; EMD-12693; -. DR EMDB; EMD-12694; -. DR EMDB; EMD-12695; -. DR EMDB; EMD-12936; -. DR EMDB; EMD-12937; -. DR EMDB; EMD-13180; -. DR EMDB; EMD-13458; -. DR EMDB; EMD-13459; -. DR EMDB; EMD-13461; -. DR EMDB; EMD-13462; -. DR EMDB; EMD-13463; -. DR EMDB; EMD-13464; -. DR EMDB; EMD-13465; -. DR EMDB; EMD-13805; -. DR EMDB; EMD-13952; -. DR EMDB; EMD-13955; -. DR EMDB; EMD-13956; -. DR EMDB; EMD-13958; -. DR EMDB; EMD-14121; -. DR EMDB; EMD-14454; -. DR EMDB; EMD-14846; -. DR EMDB; EMD-14850; -. DR EMDB; EMD-14864; -. DR EMDB; EMD-14865; -. DR EMDB; EMD-14956; -. DR EMDB; EMD-15116; -. DR EMDB; EMD-15488; -. DR EMDB; EMD-15558; -. DR EMDB; EMD-15712; -. DR EMDB; EMD-15793; -. DR EMDB; EMD-15905; -. DR EMDB; EMD-16015; -. DR EMDB; EMD-16029; -. DR EMDB; EMD-16031; -. DR EMDB; EMD-16047; -. DR EMDB; EMD-16057; -. DR EMDB; EMD-16059; -. DR EMDB; EMD-16062; -. DR EMDB; EMD-16065; -. DR EMDB; EMD-16081; -. DR EMDB; EMD-16082; -. DR EMDB; EMD-16494; -. DR EMDB; EMD-16495; -. DR EMDB; EMD-16496; -. DR EMDB; EMD-16497; -. DR EMDB; EMD-16501; -. DR EMDB; EMD-16502; -. DR EMDB; EMD-16613; -. DR EMDB; EMD-16641; -. DR EMDB; EMD-16652; -. DR EMDB; EMD-17346; -. DR EMDB; EMD-17347; -. DR EMDB; EMD-17348; -. DR EMDB; EMD-17631; -. DR EMDB; EMD-17667; -. DR EMDB; EMD-17743; -. DR EMDB; EMD-17959; -. DR EMDB; EMD-18320; -. DR EMDB; EMD-18458; -. DR EMDB; EMD-18534; -. DR EMDB; EMD-18875; -. DR EMDB; EMD-18950; -. DR EMDB; EMD-19004; -. DR EMDB; EMD-19054; -. DR EMDB; EMD-19055; -. DR EMDB; EMD-19058; -. DR EMDB; EMD-19059; -. DR EMDB; EMD-19426; -. DR EMDB; EMD-19427; -. DR EMDB; EMD-19428; -. DR EMDB; EMD-19429; -. DR EMDB; EMD-20048; -. DR EMDB; EMD-20052; -. DR EMDB; EMD-21420; -. DR EMDB; EMD-21421; -. DR EMDB; EMD-21422; -. DR EMDB; EMD-21620; -. DR EMDB; EMD-21625; -. DR EMDB; EMD-21630; -. DR EMDB; EMD-21631; -. DR EMDB; EMD-21632; -. DR EMDB; EMD-21633; -. DR EMDB; EMD-21634; -. DR EMDB; EMD-21635; -. DR EMDB; EMD-21636; -. DR EMDB; EMD-21637; -. DR EMDB; EMD-21638; -. DR EMDB; EMD-21639; -. DR EMDB; EMD-21640; -. DR EMDB; EMD-21641; -. DR EMDB; EMD-21856; -. DR EMDB; EMD-21857; -. DR EMDB; EMD-21858; -. DR EMDB; EMD-22459; -. DR EMDB; EMD-22461; -. DR EMDB; EMD-22464; -. DR EMDB; EMD-22466; -. DR EMDB; EMD-22469; -. DR EMDB; EMD-22472; -. DR EMDB; EMD-22669; -. DR EMDB; EMD-22670; -. DR EMDB; EMD-22671; -. DR EMDB; EMD-22672; -. DR EMDB; EMD-22673; -. DR EMDB; EMD-22674; -. DR EMDB; EMD-23528; -. DR EMDB; EMD-24120; -. DR EMDB; EMD-24132; -. DR EMDB; EMD-24133; -. DR EMDB; EMD-24134; -. DR EMDB; EMD-24135; -. DR EMDB; EMD-24136; -. DR EMDB; EMD-25405; -. DR EMDB; EMD-25407; -. DR EMDB; EMD-25409; -. DR EMDB; EMD-25410; -. DR EMDB; EMD-25411; -. DR EMDB; EMD-25415; -. DR EMDB; EMD-25418; -. DR EMDB; EMD-25420; -. DR EMDB; EMD-25421; -. DR EMDB; EMD-30215; -. DR EMDB; EMD-30598; -. DR EMDB; EMD-30611; -. DR EMDB; EMD-33660; -. DR EMDB; EMD-33661; -. DR EMDB; EMD-33662; -. DR EMDB; EMD-33663; -. DR EMDB; EMD-33664; -. DR EMDB; EMD-33665; -. DR EMDB; EMD-33904; -. DR EMDB; EMD-3489; -. DR EMDB; EMD-3490; -. DR EMDB; EMD-3492; -. DR EMDB; EMD-3493; -. DR EMDB; EMD-35001; -. DR EMDB; EMD-35020; -. DR EMDB; EMD-35022; -. DR EMDB; EMD-3508; -. DR EMDB; EMD-35411; -. DR EMDB; EMD-35412; -. DR EMDB; EMD-35939; -. DR EMDB; EMD-3617; -. DR EMDB; EMD-3713; -. DR EMDB; EMD-37271; -. DR EMDB; EMD-3730; -. DR EMDB; EMD-38940; -. DR EMDB; EMD-38941; -. DR EMDB; EMD-38942; -. DR EMDB; EMD-38943; -. DR EMDB; EMD-38944; -. DR EMDB; EMD-38945; -. DR EMDB; EMD-38946; -. DR EMDB; EMD-38947; -. DR EMDB; EMD-38948; -. DR EMDB; EMD-38949; -. DR EMDB; EMD-3898; -. DR EMDB; EMD-3899; -. DR EMDB; EMD-3903; -. DR EMDB; EMD-39168; -. DR EMDB; EMD-39169; -. DR EMDB; EMD-39170; -. DR EMDB; EMD-39171; -. DR EMDB; EMD-39172; -. DR EMDB; EMD-39173; -. DR EMDB; EMD-39577; -. DR EMDB; EMD-39578; -. DR EMDB; EMD-39579; -. DR EMDB; EMD-39580; -. DR EMDB; EMD-39581; -. DR EMDB; EMD-4001; -. DR EMDB; EMD-4121; -. DR EMDB; EMD-4122; -. DR EMDB; EMD-4123; -. DR EMDB; EMD-4124; -. DR EMDB; EMD-4125; -. DR EMDB; EMD-4126; -. DR EMDB; EMD-43391; -. DR EMDB; EMD-4378; -. DR EMDB; EMD-4379; -. DR EMDB; EMD-4380; -. DR EMDB; EMD-4383; -. DR EMDB; EMD-4476; -. DR EMDB; EMD-4477; -. DR EMDB; EMD-4478; -. DR EMDB; EMD-4638; -. DR EMDB; EMD-46632; -. DR EMDB; EMD-48329; -. DR EMDB; EMD-48479; -. DR EMDB; EMD-48513; -. DR EMDB; EMD-48830; -. DR EMDB; EMD-48831; -. DR EMDB; EMD-50296; -. DR EMDB; EMD-51318; -. DR EMDB; EMD-51340; -. DR EMDB; EMD-51350; -. DR EMDB; EMD-51351; -. DR EMDB; EMD-51352; -. DR EMDB; EMD-51353; -. DR EMDB; EMD-51354; -. DR EMDB; EMD-51355; -. DR EMDB; EMD-51679; -. DR EMDB; EMD-51758; -. DR EMDB; EMD-51833; -. DR EMDB; EMD-51834; -. DR EMDB; EMD-51835; -. DR EMDB; EMD-51836; -. DR EMDB; EMD-51839; -. DR EMDB; EMD-51840; -. DR EMDB; EMD-51841; -. DR EMDB; EMD-51842; -. DR EMDB; EMD-51843; -. DR EMDB; EMD-51976; -. DR EMDB; EMD-51978; -. DR EMDB; EMD-51979; -. DR EMDB; EMD-52417; -. DR EMDB; EMD-52418; -. DR EMDB; EMD-52500; -. DR EMDB; EMD-52512; -. DR EMDB; EMD-52597; -. DR EMDB; EMD-53311; -. DR EMDB; EMD-53341; -. DR EMDB; EMD-53553; -. DR EMDB; EMD-53892; -. DR EMDB; EMD-53943; -. DR EMDB; EMD-54009; -. DR EMDB; EMD-54253; -. DR EMDB; EMD-54254; -. DR EMDB; EMD-55001; -. DR EMDB; EMD-55145; -. DR EMDB; EMD-55176; -. DR EMDB; EMD-55177; -. DR EMDB; EMD-55178; -. DR EMDB; EMD-55349; -. DR EMDB; EMD-55415; -. DR EMDB; EMD-55598; -. DR EMDB; EMD-55618; -. DR EMDB; EMD-55844; -. DR EMDB; EMD-55845; -. DR EMDB; EMD-55849; -. DR EMDB; EMD-56070; -. DR EMDB; EMD-56091; -. DR EMDB; EMD-56128; -. DR EMDB; EMD-56827; -. DR EMDB; EMD-56828; -. DR EMDB; EMD-56829; -. DR EMDB; EMD-56830; -. DR EMDB; EMD-56831; -. DR EMDB; EMD-56832; -. DR EMDB; EMD-56833; -. DR EMDB; EMD-57973; -. DR EMDB; EMD-57974; -. DR EMDB; EMD-57975; -. DR EMDB; EMD-60034; -. DR EMDB; EMD-60059; -. DR EMDB; EMD-60060; -. DR EMDB; EMD-60061; -. DR EMDB; EMD-60473; -. DR EMDB; EMD-60474; -. DR EMDB; EMD-60747; -. DR EMDB; EMD-61605; -. DR EMDB; EMD-61706; -. DR EMDB; EMD-61708; -. DR EMDB; EMD-61709; -. DR EMDB; EMD-61720; -. DR EMDB; EMD-65381; -. DR EMDB; EMD-66121; -. DR EMDB; EMD-66122; -. DR EMDB; EMD-6667; -. DR EMDB; EMD-67339; -. DR EMDB; EMD-70050; -. DR EMDB; EMD-70051; -. DR EMDB; EMD-71667; -. DR EMDB; EMD-71668; -. DR EMDB; EMD-71669; -. DR EMDB; EMD-72646; -. DR EMDB; EMD-7289; -. DR EMDB; EMD-7341; -. DR EMDB; EMD-74757; -. DR EMDB; EMD-75389; -. DR EMDB; EMD-75605; -. DR EMDB; EMD-75634; -. DR EMDB; EMD-75650; -. DR EMDB; EMD-75668; -. DR EMDB; EMD-75676; -. DR EMDB; EMD-8000; -. DR EMDB; EMD-8001; -. DR EMDB; EMD-8002; -. DR EMDB; EMD-8003; -. DR EMDB; EMD-8004; -. DR EMDB; EMD-8107; -. DR EMDB; EMD-8175; -. DR EMDB; EMD-8176; -. DR EMDB; EMD-8237; -. DR EMDB; EMD-8238; -. DR EMDB; EMD-8279; -. DR EMDB; EMD-8280; -. DR EMDB; EMD-8281; -. DR EMDB; EMD-8282; -. DR EMDB; EMD-8505; -. DR EMDB; EMD-8615; -. DR EMDB; EMD-8616; -. DR EMDB; EMD-8617; -. DR EMDB; EMD-8618; -. DR EMDB; EMD-8619; -. DR EMDB; EMD-8620; -. DR EMDB; EMD-8813; -. DR EMDB; EMD-8814; -. DR EMDB; EMD-8815; -. DR EMDB; EMD-8828; -. DR SMR; P0C018; -. DR BioGRID; 4263396; 12. DR BioGRID; 852116; 4. DR ComplexPortal; CPX-3807; 50S large ribosomal subunit. DR DIP; DIP-47908N; -. DR FunCoup; P0C018; 950. DR IntAct; P0C018; 53. DR STRING; 511145.b3304; -. DR jPOST; P0C018; -. DR PaxDb; 511145-b3304; -. DR EnsemblBacteria; AAC76329; AAC76329; b3304. DR GeneID; 947804; -. DR GeneID; 98390426; -. DR KEGG; ecj:JW3266; -. DR KEGG; eco:b3304; -. DR KEGG; ecoc:C3026_17960; -. DR PATRIC; fig|1411691.4.peg.3427; -. DR EchoBASE; EB0872; -. DR eggNOG; COG0256; Bacteria. DR HOGENOM; CLU_098841_0_1_6; -. DR InParanoid; P0C018; -. DR OMA; ACAYRYQ; -. DR OrthoDB; 9810939at2; -. DR PhylomeDB; P0C018; -. DR BioCyc; EcoCyc:EG10879-MONOMER; -. DR BioCyc; MetaCyc:EG10879-MONOMER; -. DR EvolutionaryTrace; P0C018; -. DR PRO; PR:P0C018; -. DR Proteomes; UP000000625; Chromosome. DR GO; GO:0005737; C:cytoplasm; IDA:ComplexPortal. DR GO; GO:0005829; C:cytosol; IDA:EcoCyc. DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IDA:EcoCyc. DR GO; GO:0008097; F:5S rRNA binding; IDA:EcoCyc. DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro. DR GO; GO:0002181; P:cytoplasmic translation; NAS:ComplexPortal. DR CDD; cd00432; Ribosomal_L18_L5e; 1. DR FunFam; 3.30.420.100:FF:000001; 50S ribosomal protein L18; 1. DR Gene3D; 3.30.420.100; -; 1. DR HAMAP; MF_01337_B; Ribosomal_uL18_B; 1. DR InterPro; IPR057268; Ribosomal_L18. DR InterPro; IPR005484; Ribosomal_uL18_bac/plant/anim. DR InterPro; IPR004389; Ribosomal_uL18_bact. DR NCBIfam; TIGR00060; L18_bact; 1. DR PANTHER; PTHR12899; 39S RIBOSOMAL PROTEIN L18, MITOCHONDRIAL; 1. DR PANTHER; PTHR12899:SF3; LARGE RIBOSOMAL SUBUNIT PROTEIN UL18M; 1. DR Pfam; PF00861; Ribosomal_L18p; 1. DR SUPFAM; SSF53137; Translational machinery components; 1. PE 1: Evidence at protein level; KW 3D-structure; Direct protein sequencing; Phosphoprotein; KW Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding; KW rRNA-binding. FT CHAIN 1..117 FT /note="Large ribosomal subunit protein uL18" FT /id="PRO_0000131258" FT REGION 1..17 FT /note="Required for binding of the 5S rRNA/L5/L18 complex FT to the 23S rRNA" FT /evidence="ECO:0000269|PubMed:353728" FT HELIX 3..21 FT /evidence="ECO:0007829|PDB:8B0X" FT STRAND 25..30 FT /evidence="ECO:0007829|PDB:8B0X" FT STRAND 32..34 FT /evidence="ECO:0007829|PDB:6WD0" FT STRAND 35..40 FT /evidence="ECO:0007829|PDB:8B0X" FT STRAND 42..45 FT /evidence="ECO:0007829|PDB:9MOR" FT STRAND 47..52 FT /evidence="ECO:0007829|PDB:8B0X" FT STRAND 53..55 FT /evidence="ECO:0007829|PDB:4V9D" FT HELIX 56..59 FT /evidence="ECO:0007829|PDB:8B0X" FT STRAND 60..63 FT /evidence="ECO:0007829|PDB:4YBB" FT STRAND 65..67 FT /evidence="ECO:0007829|PDB:9GHE" FT HELIX 68..84 FT /evidence="ECO:0007829|PDB:8B0X" FT STRAND 91..93 FT /evidence="ECO:0007829|PDB:8B0X" FT STRAND 95..97 FT /evidence="ECO:0007829|PDB:5IQR" FT HELIX 101..113 FT /evidence="ECO:0007829|PDB:8B0X" SQ SEQUENCE 117 AA; 12770 MW; CA1082FF9B5D9697 CRC64; MDKKSARIRR ATRARRKLQE LGATRLVVHR TPRHIYAQVI APNGSEVLVA ASTVEKAIAE QLKYTGNKDA AAAVGKAVAE RALEKGIKDV SFDRSGFQYH GRVQALADAA REAGLQF //