ID   YIDH_ECOLI              Reviewed;         115 AA.
AC   P0ADM0; P31445; Q2M7Y9;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   04-NOV-2026, entry version 114.
DE   RecName: Full=Inner membrane protein YidH;
GN   Name=yidH; OrderedLocusNames=b3676, JW3652;
OS   Escherichia coli (strain K12).
OC   Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
OC   Enterobacterales; Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=7686882; DOI=10.1006/geno.1993.1230;
RA   Burland V.D., Plunkett G. III, Daniels D.L., Blattner F.R.;
RT   "DNA sequence and analysis of 136 kilobases of the Escherichia coli genome:
RT   organizational symmetry around the origin of replication.";
RL   Genomics 16:551-561(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [4]
RP   TOPOLOGY [LARGE SCALE ANALYSIS].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=15919996; DOI=10.1126/science.1109730;
RA   Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT   "Global topology analysis of the Escherichia coli inner membrane
RT   proteome.";
RL   Science 308:1321-1323(2005).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: To M.tuberculosis Rv2272. {ECO:0000305}.
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DR   EMBL; L10328; AAA62028.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC76699.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77617.1; -; Genomic_DNA.
DR   PIR; E65169; E65169.
DR   RefSeq; NP_418132.1; NC_000913.3.
DR   RefSeq; WP_000703959.1; NZ_CP009789.1.
DR   AlphaFoldDB; P0ADM0; -.
DR   SMR; P0ADM0; -.
DR   BioGRID; 4262587; 6.
DR   DIP; DIP-47894N; -.
DR   FunCoup; P0ADM0; 5.
DR   STRING; 511145.b3676; -.
DR   TCDB; 9.B.51.1.1; the uncharacterized duf202/yidh (yidh) family.
DR   PaxDb; 511145-b3676; -.
DR   EnsemblBacteria; AAC76699; AAC76699; b3676.
DR   GeneID; 93778418; -.
DR   GeneID; 948190; -.
DR   KEGG; ecj:JW3652; -.
DR   KEGG; eco:b3676; -.
DR   KEGG; ecoc:C3026_19935; -.
DR   PATRIC; fig|511145.12.peg.3797; -.
DR   EchoBASE; EB1647; -.
DR   eggNOG; COG2149; Bacteria.
DR   HOGENOM; CLU_053359_4_1_6; -.
DR   InParanoid; P0ADM0; -.
DR   OMA; AAGRWMH; -.
DR   OrthoDB; 582337at2; -.
DR   PhylomeDB; P0ADM0; -.
DR   BioCyc; EcoCyc:EG11696-MONOMER; -.
DR   PRO; PR:P0ADM0; -.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR   GO; GO:0006979; P:response to oxidative stress; IMP:EcoCyc.
DR   InterPro; IPR003807; DUF202.
DR   InterPro; IPR052053; IM_YidH-like.
DR   PANTHER; PTHR34187:SF2; DUF202 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR34187; FGR18P; 1.
DR   Pfam; PF02656; DUF202; 1.
PE   1: Evidence at protein level;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..115
FT                   /note="Inner membrane protein YidH"
FT                   /id="PRO_0000169628"
FT   TOPO_DOM        1..30
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        31..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        52..53
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        54..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        75..92
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        93..113
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        114..115
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   115 AA;  12779 MW;  59E08E0F3EA7125A CRC64;
     MKISRLGEAP DYRFSLANER TFLAWIRTAL GFLAAGVGLD QLAPDFATPV IRELLALLLC
     LFSGGLAMYG YLRWLRNEKA MRLKEDLPYT NSLLIISLIL MVVAVIVMGL VLYAG
//