ID THM1_THADA Reviewed; 235 AA. AC P02883; A1IIJ1; Q8RVT0; DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot. DT 28-MAR-2018, sequence version 2. DT 02-SEP-2026, entry version 148. DE RecName: Full=Thaumatin I {ECO:0000303|PubMed:456365}; DE AltName: Full=Thaumatin-1 {ECO:0000305}; DE Flags: Precursor; OS Thaumatococcus daniellii (Katemfe) (Phrynium daniellii). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; Liliopsida; Zingiberales; Marantaceae; OC Thaumatococcus. OX NCBI_TaxID=4621; RN [1] RP NUCLEOTIDE SEQUENCE [MRNA]. RX PubMed=17897626; DOI=10.1016/j.bbrc.2007.09.021; RA Ide N., Masuda T., Kitabatake N.; RT "Effects of pre- and pro-sequence of thaumatin on the secretion by Pichia RT pastoris."; RL Biochem. Biophys. Res. Commun. 363:708-714(2007). RN [2] RP NUCLEOTIDE SEQUENCE [MRNA] OF 23-229. RX PubMed=17691810; DOI=10.1021/bp070072v; RA Ide N., Kaneko R., Wada R., Mehta A., Tamaki S., Tsuruta T., Fujita Y., RA Masuda T., Kitabatake N.; RT "Cloning of the thaumatin I cDNA and characterization of recombinant RT thaumatin I secreted by Pichia pastoris."; RL Biotechnol. Prog. 23:1023-1030(2007). RN [3] RP PROTEIN SEQUENCE OF 23-229. RX PubMed=456365; DOI=10.1111/j.1432-1033.1979.tb13029.x; RA Iyengar R.B., Smits P., van der Ouderaa F., van der Wel H., RA van Brouwershaven J., Ravestein P., Richters G., van Wassenaar P.D.; RT "The complete amino-acid sequence of the sweet protein thaumatin I."; RL Eur. J. Biochem. 96:193-204(1979). RN [4] RP X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 23-229, DISULFIDE BONDS, AND RP FUNCTION. RX PubMed=3856268; DOI=10.1073/pnas.82.5.1406; RA de Vos A.M., Hatada M., van der Wel H., Krabbendam H., Peerdeman A.F., RA Kim S.-H.; RT "Three-dimensional structure of thaumatin I, an intensely sweet protein."; RL Proc. Natl. Acad. Sci. U.S.A. 82:1406-1409(1985). RN [5] RP X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 23-229. RX PubMed=2360997; DOI=10.1080/07391102.1990.10508545; RA McPherson A., Weickmann J.; RT "X-ray analysis of new crystal forms of the sweet protein thaumatin."; RL J. Biomol. Struct. Dyn. 7:1053-1060(1990). RN [6] RP X-RAY CRYSTALLOGRAPHY (1.65 ANGSTROMS) OF 23-229. RX PubMed=1469722; DOI=10.1016/0022-2836(92)90873-i; RA Ogata C.M., Gordon P.F., de Vos A.M., Kim S.-H.; RT "Crystal structure of a sweet tasting protein thaumatin I, at 1.65-A RT resolution."; RL J. Mol. Biol. 228:893-908(1992). RN [7] RP X-RAY CRYSTALLOGRAPHY (1.98 ANGSTROMS) OF 23-229, AND DISULFIDE BONDS. RX PubMed=17327674; DOI=10.1107/s0907444906055624; RA Mueller-Dieckmann C., Panjikar S., Schmidt A., Mueller S., Kuper J., RA Geerlof A., Wilmanns M., Singh R.K., Tucker P.A., Weiss M.S.; RT "On the routine use of soft X-rays in macromolecular crystallography. Part RT IV. Efficient determination of anomalous substructures in biomacromolecules RT using longer X-ray wavelengths."; RL Acta Crystallogr. D 63:366-380(2007). RN [8] RP X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 23-229, AND DISULFIDE BONDS. RX PubMed=25384243; DOI=10.1038/nmeth.3172; RA Sugahara M., Mizohata E., Nango E., Suzuki M., Tanaka T., Masuda T., RA Tanaka R., Shimamura T., Tanaka Y., Suno C., Ihara K., Pan D., RA Kakinouchi K., Sugiyama S., Murata M., Inoue T., Tono K., Song C., Park J., RA Kameshima T., Hatsui T., Joti Y., Yabashi M., Iwata S.; RT "Grease matrix as a versatile carrier of proteins for serial RT crystallography."; RL Nat. Methods 12:61-63(2015). CC -!- FUNCTION: Taste-modifying protein; intensely sweet-tasting. It is CC 100000 times sweeter than sucrose on a molar basis. CC {ECO:0000305|PubMed:3856268}. CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle. Note=Thaumatin accumulates CC in vesicle-like organelles. {ECO:0000305}. CC -!- SIMILARITY: Belongs to the thaumatin family. {ECO:0000255|PROSITE- CC ProRule:PRU00699}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AB265690; BAF44567.1; -; mRNA. DR EMBL; AF355098; AAL83964.1; -; mRNA. DR PIR; A03377; QTTC1. DR PDB; 1LR2; X-ray; 1.80 A; A=23-229. DR PDB; 1LR3; X-ray; 1.80 A; A=23-229. DR PDB; 1LXZ; X-ray; 1.25 A; A=23-229. DR PDB; 1LY0; X-ray; 1.36 A; A=23-229. DR PDB; 1PP3; X-ray; 1.60 A; A/B=23-229. DR PDB; 1RQW; X-ray; 1.05 A; A=23-229. DR PDB; 1THI; X-ray; 3.20 A; A=23-229. DR PDB; 1THU; X-ray; 2.60 A; A=23-229. DR PDB; 1THV; X-ray; 1.75 A; A=23-229. DR PDB; 1THW; X-ray; 1.75 A; A=23-229. DR PDB; 2A7I; X-ray; 1.75 A; X=23-229. DR PDB; 2BLR; X-ray; 1.40 A; A=23-228. DR PDB; 2BLU; X-ray; 1.40 A; A=23-228. DR PDB; 2D8O; X-ray; 2.38 A; A=23-229. DR PDB; 2D8P; X-ray; 2.30 A; A=23-229. DR PDB; 2G4Y; X-ray; 1.98 A; A=23-229. DR PDB; 2OQN; X-ray; 1.90 A; A=23-229. DR PDB; 2PE7; X-ray; 1.46 A; A=23-229. DR PDB; 2VHK; X-ray; 0.94 A; A=23-228. DR PDB; 2VHR; X-ray; 0.95 A; A=23-229. DR PDB; 2VI1; X-ray; 1.04 A; A=23-229. DR PDB; 2VI2; X-ray; 1.08 A; A=23-229. DR PDB; 2VI3; X-ray; 0.98 A; A=23-229. DR PDB; 2VI4; X-ray; 1.10 A; A=23-229. DR PDB; 2VU6; X-ray; 0.95 A; A=23-229. DR PDB; 2VU7; X-ray; 1.08 A; A=23-229. DR PDB; 2WBZ; X-ray; 1.60 A; A=23-228. DR PDB; 3AL7; X-ray; 1.10 A; A=23-229. DR PDB; 3ALD; X-ray; 1.10 A; A=23-229. DR PDB; 3DZN; X-ray; 1.51 A; A=23-229. DR PDB; 3DZP; X-ray; 1.51 A; A=23-229. DR PDB; 3DZR; X-ray; 1.51 A; A=23-229. DR PDB; 3E0A; X-ray; 1.51 A; A=23-229. DR PDB; 3E3S; X-ray; 1.73 A; A=23-229. DR PDB; 3N02; X-ray; 1.50 A; A=23-228. DR PDB; 3N03; X-ray; 1.50 A; A=23-228. DR PDB; 3QY5; X-ray; 1.25 A; A=23-229. DR PDB; 3V7V; X-ray; 2.30 A; A=23-229. DR PDB; 3V82; X-ray; 2.30 A; A=23-229. DR PDB; 3V84; X-ray; 2.30 A; A=23-229. DR PDB; 3V87; X-ray; 2.30 A; A=23-229. DR PDB; 3V88; X-ray; 2.30 A; A=23-229. DR PDB; 3V8A; X-ray; 2.30 A; A=23-229. DR PDB; 3VCE; X-ray; 2.30 A; A=23-229. DR PDB; 3VCG; X-ray; 2.30 A; A=23-229. DR PDB; 3VCH; X-ray; 2.30 A; A=23-229. DR PDB; 3VCI; X-ray; 2.30 A; A=23-229. DR PDB; 3VCJ; X-ray; 2.30 A; A=23-229. DR PDB; 3VCK; X-ray; 2.30 A; A=23-229. DR PDB; 3VHF; X-ray; 1.39 A; A=23-229. DR PDB; 3VHG; X-ray; 1.00 A; A=23-229. DR PDB; 3VJQ; X-ray; 1.00 A; A=23-229. DR PDB; 3WXS; X-ray; 2.00 A; A=23-229. DR PDB; 3X3O; X-ray; 1.48 A; A=23-229. DR PDB; 3X3P; X-ray; 1.48 A; A=23-229. DR PDB; 3X3Q; X-ray; 1.50 A; A=23-229. DR PDB; 3X3R; X-ray; 1.52 A; A=23-229. DR PDB; 3X3S; X-ray; 1.46 A; A=23-229. DR PDB; 3X3T; X-ray; 1.50 A; A=23-229. DR PDB; 3ZEJ; X-ray; 1.55 A; A=23-229. DR PDB; 4AXR; X-ray; 1.38 A; A=23-229. DR PDB; 4AXU; X-ray; 1.38 A; A=23-228. DR PDB; 4BAL; X-ray; 1.30 A; A=23-229. DR PDB; 4BAR; X-ray; 1.20 A; A=23-229. DR PDB; 4C3C; X-ray; 1.80 A; A=23-229. DR PDB; 4DC5; X-ray; 1.48 A; A=23-229. DR PDB; 4DC6; X-ray; 1.48 A; A=23-229. DR PDB; 4DIY; X-ray; 1.98 A; A=23-229. DR PDB; 4DIZ; X-ray; 1.98 A; A=23-229. DR PDB; 4DJ0; X-ray; 1.98 A; A=23-229. DR PDB; 4DJ1; X-ray; 1.98 A; A=23-229. DR PDB; 4EK0; X-ray; 1.52 A; A=23-229. DR PDB; 4EKA; X-ray; 1.55 A; A=23-229. DR PDB; 4EKB; X-ray; 1.52 A; A=23-229. DR PDB; 4EKH; X-ray; 1.75 A; A=23-229. DR PDB; 4EKO; X-ray; 1.52 A; A=23-229. DR PDB; 4EKT; X-ray; 1.75 A; A=23-229. DR PDB; 4EL2; X-ray; 1.52 A; A=23-229. DR PDB; 4EL3; X-ray; 1.95 A; A=23-229. DR PDB; 4EL7; X-ray; 1.52 A; A=23-229. DR PDB; 4ELA; X-ray; 2.00 A; A=23-229. DR PDB; 4TVT; X-ray; 1.20 A; A=23-229. DR PDB; 4XVB; X-ray; 1.52 A; A=23-229. DR PDB; 4ZG3; X-ray; 1.20 A; A=23-229. DR PDB; 4ZXR; X-ray; 1.92 A; A=23-229. DR PDB; 5A47; X-ray; 1.20 A; A=23-229. DR PDB; 5AMZ; X-ray; 1.40 A; A=23-228. DR PDB; 5AVG; X-ray; 0.95 A; A=23-228. DR PDB; 5FGT; X-ray; 2.10 A; A=23-229. DR PDB; 5FGX; X-ray; 2.13 A; A=23-229. DR PDB; 5GQP; X-ray; 1.30 A; A=23-229. DR PDB; 5JVX; X-ray; 1.70 A; A=23-229. DR PDB; 5K7Q; EM; 2.50 A; A=23-229. DR PDB; 5KVW; X-ray; 1.59 A; A=23-229. DR PDB; 5KVX; X-ray; 1.59 A; A=23-229. DR PDB; 5KVZ; X-ray; 1.59 A; A=23-229. DR PDB; 5KW0; X-ray; 1.59 A; A=23-229. DR PDB; 5KW3; X-ray; 1.55 A; A=23-229. DR PDB; 5KW4; X-ray; 1.55 A; A=23-229. DR PDB; 5KW5; X-ray; 1.55 A; A=23-229. DR PDB; 5KW7; X-ray; 1.55 A; A=23-229. DR PDB; 5KW8; X-ray; 1.55 A; A=23-229. DR PDB; 5L4R; X-ray; 1.45 A; A=23-229. DR PDB; 5LH0; X-ray; 1.88 A; A=23-229. DR PDB; 5LH1; X-ray; 1.90 A; A=23-229. DR PDB; 5LH3; X-ray; 1.64 A; A=23-229. DR PDB; 5LH5; X-ray; 1.69 A; A=23-229. DR PDB; 5LH6; X-ray; 2.16 A; A=23-229. DR PDB; 5LH7; X-ray; 2.28 A; A=23-229. DR PDB; 5LMH; X-ray; 1.96 A; A=23-229. DR PDB; 5LN0; X-ray; 1.95 A; A=23-229. DR PDB; 5MJG; X-ray; 2.10 A; A=23-229. DR PDB; 5SW0; X-ray; 1.27 A; A=23-229. DR PDB; 5SW1; X-ray; 1.10 A; A=23-229. DR PDB; 5SW2; X-ray; 1.20 A; A=23-229. DR PDB; 5T3G; X-ray; 1.55 A; A=23-229. DR PDB; 5TCL; X-ray; 3.20 A; A=23-229. DR PDB; 5WR8; X-ray; 1.55 A; A=23-229. DR PDB; 5X9L; X-ray; 0.90 A; A=23-229. DR PDB; 5X9M; X-ray; 0.93 A; A=23-229. DR PDB; 5YYP; X-ray; 1.01 A; A=23-229. DR PDB; 5YYQ; X-ray; 1.07 A; A=23-229. DR PDB; 5YYR; X-ray; 1.07 A; A=23-229. DR PDB; 6C5Y; X-ray; 2.50 A; A=23-229. DR PDB; 6C6W; X-ray; 2.23 A; A=23-229. DR PDB; 6COA; X-ray; 1.20 A; A=23-229. DR PDB; 6E0D; X-ray; 2.24 A; A=1-235. DR PDB; 6FJ6; X-ray; 1.08 A; A=23-229. DR PDB; 6FJ8; X-ray; 1.50 A; A=23-229. DR PDB; 6FJ9; X-ray; 1.50 A; A=23-229. DR PDB; 6G89; X-ray; 2.36 A; C=23-228. DR PDB; 6O8A; X-ray; 2.60 A; A=23-229. DR PDB; 6RVO; X-ray; 1.97 A; A=23-229. DR PDB; 6S19; X-ray; 2.65 A; A=23-229. DR PDB; 6S1D; X-ray; 2.65 A; A=23-229. DR PDB; 6S1E; X-ray; 1.95 A; A=23-229. DR PDB; 6S1G; X-ray; 2.00 A; A=23-229. DR PDB; 6SRJ; X-ray; 2.30 A; A=23-229. DR PDB; 6SRK; X-ray; 2.30 A; A=23-229. DR PDB; 6SRL; X-ray; 2.30 A; A=23-229. DR PDB; 6SRO; X-ray; 2.30 A; A=23-229. DR PDB; 6SRP; X-ray; 2.30 A; A=23-229. DR PDB; 6SRQ; X-ray; 2.30 A; A=23-229. DR PDB; 6YBX; X-ray; 1.14 A; A=23-229. DR PDB; 6YC5; X-ray; 1.35 A; A=23-229. DR PDB; 6ZHN; EM; 2.76 A; A=23-229. DR PDB; 7AC3; X-ray; 1.65 A; A=23-229. DR PDB; 7AT6; X-ray; 1.46 A; A=23-229. DR PDB; 7LFG; X-ray; 1.22 A; A=23-229. DR PDB; 7LJV; X-ray; 1.48 A; A=23-229. DR PDB; 7LJW; X-ray; 1.22 A; A=23-229. DR PDB; 7LJZ; X-ray; 1.29 A; A=23-229. DR PDB; 7LK5; X-ray; 1.38 A; A=23-229. DR PDB; 7LK6; X-ray; 1.48 A; A=23-229. DR PDB; 7LNB; X-ray; 1.22 A; A=23-229. DR PDB; 7LNC; X-ray; 1.22 A; A=23-229. DR PDB; 7LND; X-ray; 1.22 A; A=23-229. DR PDB; 7O44; X-ray; 2.00 A; A=23-229. DR PDB; 7O51; X-ray; 2.20 A; A=23-229. DR PDB; 7O53; X-ray; 2.20 A; A=23-229. DR PDB; 7O5J; X-ray; 2.05 A; A=23-229. DR PDB; 7O5K; X-ray; 2.05 A; A=23-229. DR PDB; 7VCG; X-ray; 1.25 A; A=23-228. DR PDB; 7WXT; X-ray; 1.70 A; A=23-228. DR PDB; 8A9F; X-ray; 1.88 A; AAA=23-229. DR PDB; 8ENA; X-ray; 2.50 A; A=23-229. DR PDB; 8F01; X-ray; 1.80 A; A=23-229. DR PDB; 8F03; X-ray; 1.39 A; A=23-229. DR PDB; 8FZW; X-ray; 1.48 A; A=23-229. DR PDB; 8HVE; X-ray; 1.13 A; A=23-229. DR PDB; 8HVF; X-ray; 1.13 A; A=23-229. DR PDB; 8JZ8; X-ray; 0.89 A; A=23-229. DR PDB; 8RS2; X-ray; 1.70 A; X=1-235. DR PDB; 8RS3; X-ray; 1.70 A; X=1-235. DR PDB; 8RSD; X-ray; 1.70 A; X=1-235. DR PDB; 8YK6; X-ray; 0.99 A; A=23-229. DR PDB; 9EPE; X-ray; 1.52 A; A=23-229. DR PDB; 9EQR; X-ray; 1.45 A; A=23-229. DR PDB; 9EQS; X-ray; 1.46 A; A=23-229. DR PDB; 9EQT; X-ray; 1.49 A; A=23-229. DR PDB; 9EQU; X-ray; 1.30 A; A=23-229. DR PDB; 9EQV; X-ray; 1.48 A; A=23-229. DR PDB; 9EQX; X-ray; 1.41 A; A=23-229. DR PDB; 9EQY; X-ray; 1.37 A; A=23-229. DR PDB; 9EQZ; X-ray; 1.48 A; A=23-229. DR PDB; 9ER0; X-ray; 1.44 A; A=23-229. DR PDB; 9ER1; X-ray; 1.43 A; A=23-229. DR PDB; 9FTS; X-ray; 1.75 A; A=23-229. DR PDB; 9FTU; X-ray; 1.75 A; A=23-229. DR PDB; 9FTV; X-ray; 1.75 A; A=23-229. DR PDB; 9FX4; X-ray; 1.59 A; A=1-235. DR PDB; 9FX5; X-ray; 1.59 A; A=1-235. DR PDB; 9G2J; X-ray; 1.69 A; A=23-229. DR PDB; 9P14; X-ray; 1.78 A; A=23-229. DR PDB; 9P15; X-ray; 1.67 A; A=23-229. DR PDB; 9QQC; X-ray; 1.80 A; A=23-229. DR PDB; 9QQG; X-ray; 2.40 A; A=23-229. DR PDB; 9QXW; X-ray; 1.68 A; A=23-228. DR PDB; 9QXY; X-ray; 1.60 A; A=23-228. DR AlphaFoldDB; P02883; -. DR EMDB; EMD-8219; -. DR MDRepo; P02883; -. DR PCDDB; P02883; -. DR SMR; P02883; -. DR Allergome; 9233; Tha da TLP. DR EvolutionaryTrace; P02883; -. DR GO; GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-SubCell. DR CDD; cd09217; TLP-P; 1. DR FunFam; 2.60.110.10:FF:000003; Thaumatin I; 1. DR Gene3D; 2.60.110.10; Thaumatin; 1. DR InterPro; IPR037176; Osmotin/thaumatin-like_sf. DR InterPro; IPR001938; Thaumatin. DR InterPro; IPR017949; Thaumatin_CS. DR PANTHER; PTHR31048; OS03G0233200 PROTEIN; 1. DR Pfam; PF00314; Thaumatin; 1. DR PIRSF; PIRSF002703; Thaumatin; 1. DR PRINTS; PR00347; THAUMATIN. DR SMART; SM00205; THN; 1. DR SUPFAM; SSF49870; Osmotin, thaumatin-like protein; 1. DR PROSITE; PS00316; THAUMATIN_1; 1. DR PROSITE; PS51367; THAUMATIN_2; 1. DR PDBsum; 1LR2; -. DR PDBsum; 1LR3; -. DR PDBsum; 1LXZ; -. DR PDBsum; 1LY0; -. DR PDBsum; 1PP3; -. DR PDBsum; 1RQW; -. DR PDBsum; 1THI; -. DR PDBsum; 1THU; -. DR PDBsum; 1THV; -. DR PDBsum; 1THW; -. DR PDBsum; 2A7I; -. DR PDBsum; 2BLR; -. DR PDBsum; 2BLU; -. DR PDBsum; 2D8O; -. DR PDBsum; 2D8P; -. DR PDBsum; 2G4Y; -. DR PDBsum; 2OQN; -. DR PDBsum; 2PE7; -. DR PDBsum; 2VHK; -. DR PDBsum; 2VHR; -. DR PDBsum; 2VI1; -. DR PDBsum; 2VI2; -. DR PDBsum; 2VI3; -. DR PDBsum; 2VI4; -. DR PDBsum; 2VU6; -. DR PDBsum; 2VU7; -. DR PDBsum; 2WBZ; -. DR PDBsum; 3AL7; -. DR PDBsum; 3ALD; -. DR PDBsum; 3DZN; -. DR PDBsum; 3DZP; -. DR PDBsum; 3DZR; -. DR PDBsum; 3E0A; -. DR PDBsum; 3E3S; -. DR PDBsum; 3N02; -. DR PDBsum; 3N03; -. DR PDBsum; 3QY5; -. DR PDBsum; 3V7V; -. DR PDBsum; 3V82; -. DR PDBsum; 3V84; -. DR PDBsum; 3V87; -. DR PDBsum; 3V88; -. DR PDBsum; 3V8A; -. DR PDBsum; 3VCE; -. DR PDBsum; 3VCG; -. DR PDBsum; 3VCH; -. DR PDBsum; 3VCI; -. DR PDBsum; 3VCJ; -. DR PDBsum; 3VCK; -. DR PDBsum; 3VHF; -. DR PDBsum; 3VHG; -. DR PDBsum; 3VJQ; -. DR PDBsum; 3WXS; -. DR PDBsum; 3X3O; -. DR PDBsum; 3X3P; -. DR PDBsum; 3X3Q; -. DR PDBsum; 3X3R; -. DR PDBsum; 3X3S; -. DR PDBsum; 3X3T; -. DR PDBsum; 3ZEJ; -. DR PDBsum; 4AXR; -. DR PDBsum; 4AXU; -. DR PDBsum; 4BAL; -. DR PDBsum; 4BAR; -. DR PDBsum; 4C3C; -. DR PDBsum; 4DC5; -. DR PDBsum; 4DC6; -. DR PDBsum; 4DIY; -. DR PDBsum; 4DIZ; -. DR PDBsum; 4DJ0; -. DR PDBsum; 4DJ1; -. DR PDBsum; 4EK0; -. DR PDBsum; 4EKA; -. DR PDBsum; 4EKB; -. DR PDBsum; 4EKH; -. DR PDBsum; 4EKO; -. DR PDBsum; 4EKT; -. DR PDBsum; 4EL2; -. DR PDBsum; 4EL3; -. DR PDBsum; 4EL7; -. DR PDBsum; 4ELA; -. DR PDBsum; 4TVT; -. DR PDBsum; 4XVB; -. DR PDBsum; 4ZG3; -. DR PDBsum; 4ZXR; -. DR PDBsum; 5A47; -. DR PDBsum; 5AMZ; -. DR PDBsum; 5AVG; -. DR PDBsum; 5FGT; -. DR PDBsum; 5FGX; -. DR PDBsum; 5GQP; -. DR PDBsum; 5JVX; -. DR PDBsum; 5K7Q; -. DR PDBsum; 5KVW; -. DR PDBsum; 5KVX; -. DR PDBsum; 5KVZ; -. DR PDBsum; 5KW0; -. DR PDBsum; 5KW3; -. DR PDBsum; 5KW4; -. DR PDBsum; 5KW5; -. DR PDBsum; 5KW7; -. DR PDBsum; 5KW8; -. DR PDBsum; 5L4R; -. DR PDBsum; 5LH0; -. DR PDBsum; 5LH1; -. DR PDBsum; 5LH3; -. DR PDBsum; 5LH5; -. DR PDBsum; 5LH6; -. DR PDBsum; 5LH7; -. DR PDBsum; 5LMH; -. DR PDBsum; 5LN0; -. DR PDBsum; 5MJG; -. DR PDBsum; 5SW0; -. DR PDBsum; 5SW1; -. DR PDBsum; 5SW2; -. DR PDBsum; 5T3G; -. DR PDBsum; 5TCL; -. DR PDBsum; 5WR8; -. DR PDBsum; 5X9L; -. DR PDBsum; 5X9M; -. DR PDBsum; 5YYP; -. DR PDBsum; 5YYQ; -. DR PDBsum; 5YYR; -. DR PDBsum; 6C5Y; -. DR PDBsum; 6C6W; -. DR PDBsum; 6COA; -. DR PDBsum; 6E0D; -. DR PDBsum; 6FJ6; -. DR PDBsum; 6FJ8; -. DR PDBsum; 6FJ9; -. DR PDBsum; 6G89; -. DR PDBsum; 6O8A; -. DR PDBsum; 6RVO; -. DR PDBsum; 6S19; -. DR PDBsum; 6S1D; -. DR PDBsum; 6S1E; -. DR PDBsum; 6S1G; -. DR PDBsum; 6SRJ; -. DR PDBsum; 6SRK; -. DR PDBsum; 6SRL; -. DR PDBsum; 6SRO; -. DR PDBsum; 6SRP; -. DR PDBsum; 6SRQ; -. DR PDBsum; 6YBX; -. DR PDBsum; 6YC5; -. DR PDBsum; 6ZHN; -. DR PDBsum; 7AC3; -. DR PDBsum; 7AT6; -. DR PDBsum; 7LFG; -. DR PDBsum; 7LJV; -. DR PDBsum; 7LJW; -. DR PDBsum; 7LJZ; -. DR PDBsum; 7LK5; -. DR PDBsum; 7LK6; -. DR PDBsum; 7LNB; -. DR PDBsum; 7LNC; -. DR PDBsum; 7LND; -. DR PDBsum; 7O44; -. DR PDBsum; 7O51; -. DR PDBsum; 7O53; -. DR PDBsum; 7O5J; -. DR PDBsum; 7O5K; -. DR PDBsum; 7VCG; -. DR PDBsum; 7WXT; -. DR PDBsum; 8A9F; -. DR PDBsum; 8ENA; -. DR PDBsum; 8F01; -. DR PDBsum; 8F03; -. DR PDBsum; 8FZW; -. DR PDBsum; 8HVE; -. DR PDBsum; 8HVF; -. DR PDBsum; 8JZ8; -. DR PDBsum; 8RS2; -. DR PDBsum; 8RS3; -. DR PDBsum; 8RSD; -. DR PDBsum; 8YK6; -. DR PDBsum; 9EPE; -. DR PDBsum; 9EQR; -. DR PDBsum; 9EQS; -. DR PDBsum; 9EQT; -. DR PDBsum; 9EQU; -. DR PDBsum; 9EQV; -. DR PDBsum; 9EQX; -. DR PDBsum; 9EQY; -. DR PDBsum; 9EQZ; -. DR PDBsum; 9ER0; -. DR PDBsum; 9ER1; -. DR PDBsum; 9FTS; -. DR PDBsum; 9FTU; -. DR PDBsum; 9FTV; -. DR PDBsum; 9FX4; -. DR PDBsum; 9FX5; -. DR PDBsum; 9G2J; -. DR PDBsum; 9P14; -. DR PDBsum; 9P15; -. DR PDBsum; 9QQC; -. DR PDBsum; 9QQG; -. DR PDBsum; 9QXW; -. DR PDBsum; 9QXY; -. PE 1: Evidence at protein level; KW 3D-structure; Cytoplasmic vesicle; Direct protein sequencing; KW Disulfide bond; Signal; Taste-modifying protein. FT SIGNAL 1..22 FT /evidence="ECO:0000269|PubMed:456365" FT CHAIN 23..229 FT /note="Thaumatin I" FT /evidence="ECO:0000269|PubMed:456365" FT /id="PRO_0000096221" FT PROPEP 230..235 FT /note="Removed in mature form" FT /evidence="ECO:0000269|PubMed:456365" FT /id="PRO_0000443721" FT DISULFID 31..226 FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00699, FT ECO:0000269|PubMed:17327674, ECO:0000269|PubMed:25384243, FT ECO:0000269|PubMed:3856268, ECO:0007744|PDB:2G4Y, FT ECO:0007744|PDB:3WXS" FT DISULFID 78..88 FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00699, FT ECO:0000269|PubMed:17327674, ECO:0000269|PubMed:25384243, FT ECO:0000269|PubMed:3856268, ECO:0007744|PDB:2G4Y, FT ECO:0007744|PDB:3WXS" FT DISULFID 93..99 FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00699, FT ECO:0000269|PubMed:17327674, ECO:0000269|PubMed:25384243, FT ECO:0000269|PubMed:3856268, ECO:0007744|PDB:2G4Y, FT ECO:0007744|PDB:3WXS" FT DISULFID 143..215 FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00699, FT ECO:0000269|PubMed:17327674, ECO:0000269|PubMed:25384243, FT ECO:0000269|PubMed:3856268, ECO:0007744|PDB:2G4Y, FT ECO:0007744|PDB:3WXS" FT DISULFID 148..199 FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00699, FT ECO:0000269|PubMed:17327674, ECO:0000269|PubMed:25384243, FT ECO:0000269|PubMed:3856268, ECO:0007744|PDB:2G4Y, FT ECO:0007744|PDB:3WXS" FT DISULFID 156..167 FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00699, FT ECO:0000269|PubMed:17327674, ECO:0000269|PubMed:25384243, FT ECO:0000269|PubMed:3856268, ECO:0007744|PDB:2G4Y, FT ECO:0007744|PDB:3WXS" FT DISULFID 171..180 FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00699, FT ECO:0000269|PubMed:17327674, ECO:0000269|PubMed:25384243, FT ECO:0000269|PubMed:3856268, ECO:0007744|PDB:2G4Y, FT ECO:0007744|PDB:3WXS" FT DISULFID 181..186 FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00699, FT ECO:0000269|PubMed:17327674, ECO:0000269|PubMed:25384243, FT ECO:0000269|PubMed:3856268, ECO:0007744|PDB:2G4Y, FT ECO:0007744|PDB:3WXS" FT STRAND 24..29 FT /evidence="ECO:0007829|PDB:8JZ8" FT STRAND 31..33 FT /evidence="ECO:0007829|PDB:8JZ8" FT STRAND 35..40 FT /evidence="ECO:0007829|PDB:8JZ8" FT STRAND 42..53 FT /evidence="ECO:0007829|PDB:8JZ8" FT STRAND 58..62 FT /evidence="ECO:0007829|PDB:8JZ8" FT STRAND 69..80 FT /evidence="ECO:0007829|PDB:8JZ8" FT STRAND 84..91 FT /evidence="ECO:0007829|PDB:8JZ8" FT STRAND 96..98 FT /evidence="ECO:0007829|PDB:8JZ8" FT HELIX 102..104 FT /evidence="ECO:0007829|PDB:8JZ8" FT STRAND 109..116 FT /evidence="ECO:0007829|PDB:8JZ8" FT STRAND 119..125 FT /evidence="ECO:0007829|PDB:8JZ8" FT STRAND 130..132 FT /evidence="ECO:0007829|PDB:5X9L" FT STRAND 134..143 FT /evidence="ECO:0007829|PDB:8JZ8" FT STRAND 146..148 FT /evidence="ECO:0007829|PDB:8JZ8" FT HELIX 152..155 FT /evidence="ECO:0007829|PDB:8JZ8" FT HELIX 158..160 FT /evidence="ECO:0007829|PDB:8JZ8" FT STRAND 165..167 FT /evidence="ECO:0007829|PDB:8JZ8" FT HELIX 170..174 FT /evidence="ECO:0007829|PDB:8JZ8" FT HELIX 177..180 FT /evidence="ECO:0007829|PDB:8JZ8" FT TURN 181..183 FT /evidence="ECO:0007829|PDB:5X9L" FT HELIX 190..198 FT /evidence="ECO:0007829|PDB:8JZ8" FT STRAND 202..205 FT /evidence="ECO:0007829|PDB:5KVW" FT HELIX 208..210 FT /evidence="ECO:0007829|PDB:2VU6" FT STRAND 213..216 FT /evidence="ECO:0007829|PDB:8JZ8" FT STRAND 221..226 FT /evidence="ECO:0007829|PDB:8JZ8" SQ SEQUENCE 235 AA; 25440 MW; 9E1A62D6B1EE8FEF CRC64; MAATTCFFFL FPFLLLLTLS RAATFEIVNR CSYTVWAAAS KGDAALDAGG RQLNSGESWT INVEPGTNGG KIWARTDCYF DDSGSGICKT GDCGGLLRCK RFGRPPTTLA EFSLNQYGKD YIDISNIKGF NVPMDFSPTT RGCRGVRCAA DIVGQCPAKL KAPGGGCNDA CTVFQTSEYC CTTGKCGPTE YSRFFKRLCP DAFSYVLDKP TTVTCPGSSN YRVTFCPTAL ELEDE //