ID   HVM47_MOUSE             Reviewed;         113 AA.
AC   P01823;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   02-SEP-2026, entry version 112.
DE   RecName: Full=Ig heavy chain V region 36-60;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   STRAIN=A/J;
RX   PubMed=6414509; DOI=10.1021/bi00287a020;
RA   Juszczak E.C., Margolies M.N.;
RT   "Amino acid sequence of the heavy chain variable region from the A/J mouse
RT   anti-arsonate monoclonal antibody 36-60 bearing a minor idiotype.";
RL   Biochemistry 22:4291-4296(1983).
CC   -!- MISCELLANEOUS: This chain was isolated from an antiarsonate monoclonal
CC       antibody of the IgG2a subclass. It represents a second idiotype family
CC       characteristic of the antiarsonate response of strain A/J mice.
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DR   PIR; A02098; G2MS60.
DR   PDB; 1C08; X-ray; 2.30 A; B=1-113.
DR   PDB; 1IC4; X-ray; 2.50 A; H=1-113.
DR   PDB; 1IC5; X-ray; 2.30 A; H=1-113.
DR   PDB; 1IC7; X-ray; 2.10 A; H=1-113.
DR   PDB; 1J1O; X-ray; 1.80 A; H=1-113.
DR   PDB; 1J1P; X-ray; 1.80 A; H=1-113.
DR   PDB; 1J1X; X-ray; 1.80 A; H=1-113.
DR   PDB; 2DQC; X-ray; 1.80 A; H=1-113.
DR   PDB; 2DQD; X-ray; 1.80 A; H=1-113.
DR   PDB; 2DQE; X-ray; 1.90 A; H=1-113.
DR   PDB; 2DQF; X-ray; 2.50 A; B/E=1-113.
DR   PDB; 2DQG; X-ray; 2.30 A; H=1-113.
DR   PDB; 2DQH; X-ray; 2.30 A; H=1-113.
DR   PDB; 2DQI; X-ray; 2.00 A; H=1-113.
DR   PDB; 2DQJ; X-ray; 1.80 A; H=1-113.
DR   PDB; 4CKD; EM; 13.00 A; H/I/J/K=1-113.
DR   AlphaFoldDB; P01823; -.
DR   SMR; P01823; -.
DR   FunCoup; P01823; 603.
DR   iPTMnet; P01823; -.
DR   PhosphoSitePlus; P01823; -.
DR   InParanoid; P01823; -.
DR   EvolutionaryTrace; P01823; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; P01823; protein.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-ARBA.
DR   GO; GO:0003823; F:antigen binding; IBA:GO_Central.
DR   GO; GO:0016064; P:immunoglobulin mediated immune response; IBA:GO_Central.
DR   FunFam; 2.60.40.10:FF:002253; Ig heavy chain V region 36-60; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   InterPro; IPR050199; IgHV.
DR   PANTHER; PTHR23266; IMMUNOGLOBULIN HEAVY CHAIN; 1.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
DR   PDBsum; 1C08; -.
DR   PDBsum; 1IC4; -.
DR   PDBsum; 1IC5; -.
DR   PDBsum; 1IC7; -.
DR   PDBsum; 1J1O; -.
DR   PDBsum; 1J1P; -.
DR   PDBsum; 1J1X; -.
DR   PDBsum; 2DQC; -.
DR   PDBsum; 2DQD; -.
DR   PDBsum; 2DQE; -.
DR   PDBsum; 2DQF; -.
DR   PDBsum; 2DQG; -.
DR   PDBsum; 2DQH; -.
DR   PDBsum; 2DQI; -.
DR   PDBsum; 2DQJ; -.
DR   PDBsum; 4CKD; -.
PE   1: Evidence at protein level;
KW   3D-structure; Adaptive immunity; Direct protein sequencing; Immunity;
KW   Immunoglobulin; Reference proteome.
FT   CHAIN           1..>113
FT                   /note="Ig heavy chain V region 36-60"
FT                   /id="PRO_0000059896"
FT   NON_TER         113
FT   STRAND          3..8
FT                   /evidence="ECO:0007829|PDB:1J1O"
FT   STRAND          10..12
FT                   /evidence="ECO:0007829|PDB:1J1O"
FT   STRAND          18..27
FT                   /evidence="ECO:0007829|PDB:1J1O"
FT   HELIX           29..31
FT                   /evidence="ECO:0007829|PDB:1J1O"
FT   STRAND          34..40
FT                   /evidence="ECO:0007829|PDB:1J1O"
FT   TURN            41..43
FT                   /evidence="ECO:0007829|PDB:1J1O"
FT   STRAND          44..51
FT                   /evidence="ECO:0007829|PDB:1J1O"
FT   STRAND          57..59
FT                   /evidence="ECO:0007829|PDB:1J1O"
FT   HELIX           61..63
FT                   /evidence="ECO:0007829|PDB:1J1O"
FT   STRAND          67..72
FT                   /evidence="ECO:0007829|PDB:1J1O"
FT   TURN            73..76
FT                   /evidence="ECO:0007829|PDB:1J1O"
FT   STRAND          77..82
FT                   /evidence="ECO:0007829|PDB:1J1O"
FT   HELIX           87..89
FT                   /evidence="ECO:0007829|PDB:1J1O"
FT   STRAND          91..97
FT                   /evidence="ECO:0007829|PDB:1J1O"
FT   STRAND          107..111
FT                   /evidence="ECO:0007829|PDB:1J1O"
SQ   SEQUENCE   113 AA;  12734 MW;  38DC0E0E3F5075B7 CRC64;
     EVQLQESGPS LVKPSQTLSL TCSVTGDSIT SDYWNWIRKF PGNKLEHMGY ISYSGSTYYN
     PSLKSRISIT RDTSKNQYYL QLNSVTSEDT ATYYCTSLRF AYWGQGTLVT VSA
//