ID   F7ZIE4_ROSLO            Unreviewed;       146 AA.
AC   F7ZIE4;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   02-SEP-2026, entry version 59.
DE   SubName: Full=Zinc uptake regulation protein Zur {ECO:0000313|EMBL:AEI92463.1};
GN   Name=zur {ECO:0000313|EMBL:AEI92463.1};
GN   OrderedLocusNames=RLO149_c004350 {ECO:0000313|EMBL:AEI92463.1};
OS   Roseobacter litoralis (strain ATCC 49566 / DSM 6996 / JCM 21268 / NBRC
OS   15278 / OCh 149).
OC   Bacteria; Pseudomonadati; Pseudomonadota; Alphaproteobacteria;
OC   Rhodobacterales; Roseobacteraceae; Roseobacter.
OX   NCBI_TaxID=391595 {ECO:0000313|EMBL:AEI92463.1, ECO:0000313|Proteomes:UP000001353};
RN   [1] {ECO:0000313|EMBL:AEI92463.1, ECO:0000313|Proteomes:UP000001353}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49566 / DSM 6996 / JCM 21268 / NBRC 15278 / OCh 149
RC   {ECO:0000313|Proteomes:UP000001353};
RX   PubMed=21693016; DOI=10.1186/1471-2164-12-324;
RA   Kalhoefer D., Thole S., Voget S., Lehmann R., Liesegang H., Wollher A.,
RA   Daniel R., Simon M., Brinkhoff T.;
RT   "Comparative genome analysis and genome-guided physiological analysis of
RT   Roseobacter litoralis.";
RL   BMC Genomics 12:324-324(2011).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|PIRSR:PIRSR602481-1};
CC       Note=Binds 1 zinc ion per subunit. {ECO:0000256|PIRSR:PIRSR602481-1};
CC   -!- SIMILARITY: Belongs to the Fur family. {ECO:0000256|ARBA:ARBA00007957}.
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DR   EMBL; CP002623; AEI92463.1; -; Genomic_DNA.
DR   AlphaFoldDB; F7ZIE4; -.
DR   STRING; 391595.RLO149_c004350; -.
DR   KEGG; rli:RLO149_c004350; -.
DR   eggNOG; COG0735; Bacteria.
DR   HOGENOM; CLU_096072_2_1_5; -.
DR   Proteomes; UP000001353; Chromosome.
DR   GO; GO:0005829; C:cytosol; IEA:TreeGrafter.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IEA:TreeGrafter.
DR   GO; GO:0008270; F:zinc ion binding; IEA:TreeGrafter.
DR   GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:TreeGrafter.
DR   GO; GO:1900376; P:regulation of secondary metabolite biosynthetic process; IEA:TreeGrafter.
DR   Gene3D; 3.30.1490.190; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR002481; FUR.
DR   InterPro; IPR043135; Fur_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR33202; ZINC UPTAKE REGULATION PROTEIN; 1.
DR   PANTHER; PTHR33202:SF6; ZINC UPTAKE REGULATION PROTEIN; 1.
DR   Pfam; PF01475; FUR; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR602481-1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001353};
KW   Repressor {ECO:0000256|ARBA:ARBA00022491};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PIRSR:PIRSR602481-1}.
FT   BINDING         97
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602481-1"
FT   BINDING         100
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602481-1"
FT   BINDING         137
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602481-1"
FT   BINDING         140
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602481-1"
SQ   SEQUENCE   146 AA;  15701 MW;  20E496CC61688D9C CRC64;
     MSDTLAAAEA RCAADGLRFT PVRRKVLEIL LQEHRALGAY AILDRLREDG FGSQPPVAYR
     ALDFLVLNGL AHKIEQLNAF IACVHPSEAH TPAFMICRLC DAVAETHSSP AKGALGDAAR
     ATGFRIERTI VEAEGVCPTC AEKADV
//