ID F6ZPB0_MOUSE Unreviewed; 329 AA. AC F6ZPB0; DT 27-JUL-2011, integrated into UniProtKB/TrEMBL. DT 27-JUL-2011, sequence version 1. DT 04-NOV-2026, entry version 90. DE SubName: Full=Prickle planar cell polarity protein 4 {ECO:0000313|Ensembl:ENSMUSP00000108924.2}; GN Name=Prickle4 {ECO:0000313|Ensembl:ENSMUSP00000108924.2, GN ECO:0000313|MGI:MGI:2685785}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000108924.2, ECO:0000313|Proteomes:UP000000589}; RN [1] {ECO:0000313|Ensembl:ENSMUSP00000108924.2, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000108924.2, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RG Mouse Genome Sequencing Consortium; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., RA Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of the RT mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000108924.2, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000108924.2, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=21750661; RA Church D.M., Schneider V.A., Graves T., Auger K., Cunningham F., Bouk N., RA Chen H.C., Agarwala R., McLaren W.M., Ritchie G.R., Albracht D., RA Kremitzki M., Rock S., Kotkiewicz H., Kremitzki C., Wollam A., Trani L., RA Fulton L., Fulton R., Matthews L., Whitehead S., Chow W., Torrance J., RA Dunn M., Harden G., Threadgold G., Wood J., Collins J., Heath P., RA Griffiths G., Pelan S., Grafham D., Eichler E.E., Weinstock G., RA Mardis E.R., Wilson R.K., Howe K., Flicek P., Hubbard T.; RT "Modernizing reference genome assemblies."; RL PLoS Biol. 9:e1001091-e1001091(2011). RN [3] {ECO:0000313|Ensembl:ENSMUSP00000108924.2} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000108924.2}; RG Ensembl; RL Submitted (JUL-2026) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR Ensembl; ENSMUST00000113299.6; ENSMUSP00000108924.2; ENSMUSG00000096549.11. DR VEuPathDB; HostDB:ENSMUSG00000096549; -. DR AGR; MGI:2685785; -. DR MGI; MGI:2685785; Prickle4. DR eggNOG; KOG1704; Eukaryota. DR GeneTree; ENSGT00940000161789; -. DR HOGENOM; CLU_057441_1_0_1; -. DR InParanoid; F6ZPB0; -. DR OrthoDB; 10069167at2759; -. DR Bgee; ENSMUSG00000096549; Expressed in white adipose tissue and 55 other cell types or tissues. DR ExpressionAtlas; F6ZPB0; baseline and differential. DR CDD; cd09340; LIM1_Testin_like; 1. DR CDD; cd09341; LIM2_Testin_like; 1. DR FunFam; 2.10.110.10:FF:000164; Prickle planar cell polarity protein 4; 1. DR FunFam; 2.10.110.10:FF:000093; prickle-like protein 4 isoform X3; 1. DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 2. DR InterPro; IPR010442; PET_domain. DR InterPro; IPR047120; Pk/Esn/Tes. DR InterPro; IPR001781; Znf_LIM. DR PANTHER; PTHR24211; LIM DOMAIN-CONTAINING PROTEIN; 1. DR PANTHER; PTHR24211:SF35; PRICKLE-LIKE PROTEIN 4; 1. DR Pfam; PF00412; LIM; 2. DR Pfam; PF06297; PET; 1. DR SMART; SM00132; LIM; 2. DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1. DR PROSITE; PS00478; LIM_DOMAIN_1; 1. DR PROSITE; PS50023; LIM_DOMAIN_2; 2. DR PROSITE; PS51303; PET; 1. DR GO; GO:0005912; C:adherens junction; IBA:GO_Central. DR GO; GO:0031941; C:filamentous actin; IBA:GO_Central. DR GO; GO:0001725; C:stress fiber; IBA:GO_Central. DR GO; GO:0030018; C:Z disc; IBA:GO_Central. DR GO; GO:0003779; F:actin binding; IBA:GO_Central. DR GO; GO:0051371; F:muscle alpha-actinin binding; IBA:GO_Central. DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro. DR GO; GO:0030036; P:actin cytoskeleton organization; IBA:GO_Central. DR GO; GO:0007507; P:heart development; IBA:GO_Central. DR GO; GO:0061061; P:muscle structure development; IBA:GO_Central. DR Proteomes; UP000000589; Chromosome 17. DR AlphaFoldDB; F6ZPB0; -. DR FunCoup; F6ZPB0; 3. PE 4: Predicted; KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE- KW ProRule:PRU00125}; KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE- KW ProRule:PRU00125}; Reference proteome {ECO:0000313|Proteomes:UP000000589}; KW Repeat {ECO:0000256|ARBA:ARBA00022737}; KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00125}. FT DOMAIN 1..80 FT /note="PET" FT /evidence="ECO:0000259|PROSITE:PS51303" FT DOMAIN 82..146 FT /note="LIM zinc-binding" FT /evidence="ECO:0000259|PROSITE:PS50023" FT DOMAIN 147..207 FT /note="LIM zinc-binding" FT /evidence="ECO:0000259|PROSITE:PS50023" FT REGION 216..238 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 259..321 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 282..292 FT /note="Low complexity" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 329 AA; 36077 MW; 4428010F9CC63E6D CRC64; VLPQAATCSS LGPPCLDINQ VSNWPGFRTL LQQLPPQDSD ERYCLALGEE ELAQLRLFCA QRKQKSLGQG VARLLPPKLE GYTCKKCKKL LDPGEYGVFA ARAGEQSCWH RPCFACQACG QGLINLIYFY HEGHLYCGRH HAELLRPRCP ACDQLIFSQR CTEAEGQRWH ENHFCCQDCA GPLDGGRYAL PGGSPCCPSC FSKRYRSAGS SSVGVAEGQA SFEEEGPDPS VGWNRASSDD KITSRAALLS AVPTLTLETL NGASKRQDRD GPQTPGSPIE DSPCPTCSSS SESEPEGFFF GQRLPEPWKT PENLQADDRD ISRKHCTIC //