ID   F2R3R4_STRVP            Unreviewed;       393 AA.
AC   F2R3R4;
DT   31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   31-MAY-2011, sequence version 1.
DT   04-NOV-2026, entry version 57.
DE   RecName: Full=ATP-dependent DNA ligase family profile domain-containing protein {ECO:0000259|PROSITE:PS50160};
GN   OrderedLocusNames=SVEN_5000 {ECO:0000313|EMBL:CCA58286.1};
OS   Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM
OS   4526 / NBRC 13096 / PD 04745).
OC   Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=953739 {ECO:0000313|EMBL:CCA58286.1, ECO:0000313|Proteomes:UP000006854};
RN   [1] {ECO:0000313|EMBL:CCA58286.1, ECO:0000313|Proteomes:UP000006854}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 /
RC   PD 04745 {ECO:0000313|Proteomes:UP000006854};
RX   PubMed=21463507; DOI=10.1186/1471-2164-12-175;
RA   Pullan S.T., Bibb M.J., Merrick M.;
RT   "Genome-wide analysis of the role of GlnR in Streptomyces venezuelae
RT   provides new insights into global nitrogen regulation in actinomycetes.";
RL   BMC Genomics 12:175-175(2011).
CC   -!- SIMILARITY: Belongs to the ATP-dependent DNA ligase family.
CC       {ECO:0000256|ARBA:ARBA00007572}.
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DR   EMBL; FR845719; CCA58286.1; -; Genomic_DNA.
DR   RefSeq; WP_015036185.1; NC_018750.1.
DR   AlphaFoldDB; F2R3R4; -.
DR   STRING; 953739.SVEN_5000; -.
DR   GeneID; 51865560; -.
DR   KEGG; sve:SVEN_5000; -.
DR   PATRIC; fig|953739.5.peg.135; -.
DR   eggNOG; COG1793; Bacteria.
DR   HOGENOM; CLU_008325_4_1_11; -.
DR   OMA; AAPTEWH; -.
DR   Proteomes; UP000006854; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   Gene3D; 3.30.1490.70; -; 1.
DR   Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR   InterPro; IPR050191; ATP-dep_DNA_ligase.
DR   InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR   PANTHER; PTHR45674:SF4; DNA LIGASE 1; 1.
DR   PANTHER; PTHR45674; DNA LIGASE 1/3 FAMILY MEMBER; 1.
DR   Pfam; PF01068; DNA_ligase_A_M; 1.
DR   SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR   PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE   3: Inferred from homology;
KW   Ligase {ECO:0000256|ARBA:ARBA00022598};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006854}.
FT   DOMAIN          202..295
FT                   /note="ATP-dependent DNA ligase family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50160"
FT   REGION          1..105
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..12
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        13..55
FT                   /note="Gly residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        56..67
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        74..83
FT                   /note="Low complexity"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        88..98
FT                   /note="Gly residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   393 AA;  40565 MW;  6E18F1E73B580149 CRC64;
     MSRAPDGIRG DHGAGAGAGA GVGAGVGSWG PSGAAGAGGP EGGGGAGPAR NGGPGRASAA
     PAASARGPEG GSGDPADGPG PARDPGRAGR GPAAGRGGLV VHPPVGVMRP RAADELPPQA
     APPRELQYSL KLDGFRALAF VLDDGKVVLQ SRSRRDLAPE FPGIAAHLAD QLPPGVVLDG
     ELCAYRDGRL SFTDLLRSPA DRARAGVPVS YIAFDLLAVP GRDVRGLPLR TRWELLGAAL
     SEAEPPLQRV LATLDEETAR GWFRDLQDAG VEGIVAKTLS STYRAGSTWA WRKIRHTDTS
     DGLLLGVVGP PGRPRSLLVR LADGRTVPTA PRLTPAQSRE VGALAGDRAG PLVQDPEHGP
     VRWVDPPLPV ELRQLAVRQR QDYATFIRVR SEG
//