ID D7LTR3_ARALL Unreviewed; 1104 AA. AC D7LTR3; DT 10-AUG-2010, integrated into UniProtKB/TrEMBL. DT 10-AUG-2010, sequence version 1. DT 02-SEP-2026, entry version 81. DE SubName: Full=EMB2221 {ECO:0000313|EMBL:EFH54777.1}; GN ORFNames=ARALYDRAFT_907933 {ECO:0000313|EMBL:EFH54777.1}; OS Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis. OX NCBI_TaxID=81972 {ECO:0000313|EMBL:EFH54777.1, ECO:0000313|Proteomes:UP000008694}; RN [1] {ECO:0000313|Proteomes:UP000008694} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. MN47 {ECO:0000313|Proteomes:UP000008694}; RX PubMed=21478890; DOI=10.1038/ng.807; RA Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M., RA Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G., RA Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., Schneeberger K., RA Spannagl M., Wang X., Yang L., Nasrallah M.E., Bergelson J., RA Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., Van de Peer Y., RA Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.; RT "The Arabidopsis lyrata genome sequence and the basis of rapid genome size RT change."; RL Nat. Genet. 43:476-481(2011). CC -!- FUNCTION: Required for protein transport from the endoplasmic reticulum CC to the Golgi apparatus. {ECO:0000256|ARBA:ARBA00060100}. CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum CC {ECO:0000256|ARBA:ARBA00004240}. Golgi apparatus CC {ECO:0000256|ARBA:ARBA00004555}. CC -!- SIMILARITY: Belongs to the WD repeat SEC31 family. CC {ECO:0000256|ARBA:ARBA00009358}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; GL348717; EFH54777.1; -; Genomic_DNA. DR AlphaFoldDB; D7LTR3; -. DR STRING; 81972.D7LTR3; -. DR Gramene; scaffold_503637.1; scaffold_503637.1; scaffold_503637.1. DR KEGG; aly:9314586; -. DR eggNOG; KOG0307; Eukaryota. DR HOGENOM; CLU_003033_0_0_1; -. DR OrthoDB; 542917at2759; -. DR Proteomes; UP000008694; Unassembled WGS sequence. DR GO; GO:0030127; C:COPII vesicle coat; IEA:TreeGrafter. DR GO; GO:0070971; C:endoplasmic reticulum exit site; IEA:TreeGrafter. DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell. DR GO; GO:0005198; F:structural molecule activity; IEA:TreeGrafter. DR GO; GO:0090110; P:COPII-coated vesicle cargo loading; IEA:TreeGrafter. DR GO; GO:0007029; P:endoplasmic reticulum organization; IEA:TreeGrafter. DR FunFam; 1.20.940.10:FF:000003; Protein transport protein SEC31 homolog B; 1. DR FunFam; 1.25.40.1030:FF:000004; Protein transport protein SEC31 homolog B; 1. DR FunFam; 2.130.10.10:FF:000295; Protein transport protein SEC31 homolog B; 1. DR Gene3D; 1.25.40.1030; -; 1. DR Gene3D; 1.20.940.10; Functional domain of the splicing factor Prp18; 1. DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1. DR InterPro; IPR024298; Sec16_Sec23-bd. DR InterPro; IPR040251; SEC31-like. DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf. DR InterPro; IPR019775; WD40_repeat_CS. DR InterPro; IPR036322; WD40_repeat_dom_sf. DR InterPro; IPR001680; WD40_rpt. DR PANTHER; PTHR13923; SEC31-RELATED PROTEIN; 1. DR PANTHER; PTHR13923:SF11; SECRETORY 31, ISOFORM D; 1. DR Pfam; PF12931; TPR_Sec16; 1. DR Pfam; PF00400; WD40; 2. DR SMART; SM00320; WD40; 5. DR SUPFAM; SSF50978; WD40 repeat-like; 1. DR PROSITE; PS00678; WD_REPEATS_1; 1. DR PROSITE; PS50082; WD_REPEATS_2; 2. DR PROSITE; PS50294; WD_REPEATS_REGION; 1. PE 3: Inferred from homology; KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824}; KW ER-Golgi transport {ECO:0000256|ARBA:ARBA00022892}; KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034}; KW Protein transport {ECO:0000256|ARBA:ARBA00022927}; KW Reference proteome {ECO:0000313|Proteomes:UP000008694}; KW Repeat {ECO:0000256|ARBA:ARBA00022737}; KW Transport {ECO:0000256|ARBA:ARBA00022448}; KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE- KW ProRule:PRU00221}. FT REPEAT 118..152 FT /note="WD" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221" FT REPEAT 259..301 FT /note="WD" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221" FT DOMAIN 568..764 FT /note="Sec16 Sec23-binding" FT /evidence="ECO:0000259|Pfam:PF12931" FT REGION 522..562 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 784..810 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 851..870 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 894..931 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 951..994 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 549..560 FT /note="Acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 786..810 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 894..908 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 959..977 FT /note="Low complexity" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 1104 AA; 119908 MW; BC0ED858526A5F14 CRC64; MACIKGVGRS ASVALAPDAP YMAAGTMAGA VDLSFSSSAN LEIFKLDFQS DDRDLPLVGE SPSSERFHRL AWGRNGSGSE EFSLGLIAGG LVDGNIDLWN PLSLIGSQPS ENALVGHLSV HKGPVRGLEF NAINPNLLAS GADDGEICIW DLLKPSEPSH FPLLKGSGSA TQGEISFISW NRKVQQILAS TSYNGTTVIW DLRKQKPIIN FADSVRRRCS VLQWNPNITT QIMVASDDDS SPTLKLWDMR NILSPVREFT GHQRGVIAME WCPSDSSYLL TCAKDNRTIC WDTNTAEIVA ELPAGNNWNF DVHWYPKIPG VISASSFDGK IGIYNIEGCS RYGAEENNFG TAPLRAPKWY KRPVGASFGF GGKLVSCHAR APAKGTSSIL SEVFLHSLVT EQSLVSRTSE FEAAIENGDM TSLRGLCEKK SEETESEEEK ETWGLLKIMF EEEGTSRTKL ISHLGFTLPI AENDQAVNGL SSDLNGNRLE DTAADAMEPD DSNEAAAFAM DNGEDFFNNF PAKPDTPVST SAKDFMPSDT DFSTKAEETQ EMQEEEEESS DPVFDNAIQR ALIVGDYKEA VDQCISANKM ADALVIAHVG GTALWESTRE KYLKTSSAPY MKVVSAMVNN DLRSLIYTRS HKFWKETLAL LCTFAQGEQW TTLCDALASK LMAAGNTLAA VLCYICAGNV DRTVEIWSRS LANERDGRSY AELLQDLMEK TLVLALATGN KKFSASLCKL FESYAEILAS QGLLTTAMKY LKVLDSGGLS PELSILRDRI SLSAEPETNT AASGNTQPQS TMPYNQEPTQ AQPNVLANPY DNQYQQPYTD SYYVPQASHP PMQQPTMFMP HQAQPAPQPS FTPAPASNAQ PTMRTTFVPS TPPALKNADQ YQQPTMSSHS FTGPSNNAYP VRPGPGTYAP SGPSQVGQYP NPKMPQVVAP AAGPKGFTPM ATPGVAPRSV QPASPPTQQA AAQAAPTPAT PPPTVQTADT SNVPAHQKPV IATLTRLFNE TSEALGGARA NPTKKREIED NSRKLGALFV KLNSGDISKN AADKLAQLCQ ALDNNDYSAA LQIQVLLTTN EWDECNFWLA TLKRMMVKAR QSVR //