ID   D5EAW9_METMS            Unreviewed;       261 AA.
AC   D5EAW9;
DT   15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT   15-JUN-2010, sequence version 1.
DT   04-NOV-2026, entry version 69.
DE   RecName: Full=Exosome complex component Rrp42 {ECO:0000256|HAMAP-Rule:MF_00622};
GN   Name=rrp42 {ECO:0000256|HAMAP-Rule:MF_00622};
GN   OrderedLocusNames=Mmah_0797 {ECO:0000313|EMBL:ADE36320.1};
OS   Methanohalophilus mahii (strain ATCC 35705 / DSM 5219 / SLP).
OC   Archaea; Methanobacteriati; Methanobacteriota; Stenosarchaea group;
OC   Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanohalophilus.
OX   NCBI_TaxID=547558 {ECO:0000313|EMBL:ADE36320.1, ECO:0000313|Proteomes:UP000001059};
RN   [1] {ECO:0000313|EMBL:ADE36320.1, ECO:0000313|Proteomes:UP000001059}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35705 / DSM 5219 / SLP
RC   {ECO:0000313|Proteomes:UP000001059};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA   Lykidis A., Saunders E., Brettin T., Detter J.C., Han C., Land M.,
RA   Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D.,
RA   Spring S., Schneider S., Schroeder M., Klenk H.-P., Eisen J.A.;
RT   "The complete genome of Methanohalophilus mahii DSM 5219.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Non-catalytic component of the exosome, which is a complex
CC       involved in RNA degradation. Contributes to the structuring of the
CC       Rrp41 active site. {ECO:0000256|HAMAP-Rule:MF_00622}.
CC   -!- SUBUNIT: Component of the archaeal exosome complex. Forms a hexameric
CC       ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The
CC       hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
CC       {ECO:0000256|HAMAP-Rule:MF_00622}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC       ECO:0000256|HAMAP-Rule:MF_00622}.
CC   -!- SIMILARITY: Belongs to the RNase PH family. Rrp42 subfamily.
CC       {ECO:0000256|HAMAP-Rule:MF_00622}.
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DR   EMBL; CP001994; ADE36320.1; -; Genomic_DNA.
DR   AlphaFoldDB; D5EAW9; -.
DR   STRING; 547558.Mmah_0797; -.
DR   KEGG; mmh:Mmah_0797; -.
DR   HOGENOM; CLU_038194_0_0_2; -.
DR   OMA; AADMIVH; -.
DR   Proteomes; UP000001059; Chromosome.
DR   GO; GO:0000177; C:cytoplasmic exosome (RNase complex); IEA:TreeGrafter.
DR   GO; GO:0035925; F:mRNA 3'-UTR AU-rich region binding; IEA:TreeGrafter.
DR   GO; GO:0016075; P:rRNA catabolic process; IEA:TreeGrafter.
DR   CDD; cd11365; RNase_PH_archRRP42; 1.
DR   FunFam; 3.30.230.70:FF:000017; Exosome complex component Rrp42; 1.
DR   Gene3D; 3.30.230.70; GHMP Kinase, N-terminal domain; 1.
DR   HAMAP; MF_00622; Exosome_Rrp42; 1.
DR   InterPro; IPR001247; ExoRNase_PH_dom1.
DR   InterPro; IPR015847; ExoRNase_PH_dom2.
DR   InterPro; IPR036345; ExoRNase_PH_dom2_sf.
DR   InterPro; IPR050590; Exosome_comp_Rrp42_subfam.
DR   InterPro; IPR027408; PNPase/RNase_PH_dom_sf.
DR   InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR   InterPro; IPR020869; Rrp42_archaea.
DR   NCBIfam; NF003282; rrp42; 1.
DR   PANTHER; PTHR11097:SF8; EXOSOME COMPLEX COMPONENT RRP42; 1.
DR   PANTHER; PTHR11097; EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN; 1.
DR   Pfam; PF01138; RNase_PH; 1.
DR   Pfam; PF03725; RNase_PH_C; 1.
DR   SUPFAM; SSF55666; Ribonuclease PH domain 2-like; 1.
DR   SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_00622};
KW   Exosome {ECO:0000256|ARBA:ARBA00022835, ECO:0000256|HAMAP-Rule:MF_00622};
KW   Hydrolase {ECO:0000313|EMBL:ADE36320.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001059}.
FT   DOMAIN          32..167
FT                   /note="Exoribonuclease phosphorolytic"
FT                   /evidence="ECO:0000259|Pfam:PF01138"
FT   DOMAIN          184..248
FT                   /note="Exoribonuclease phosphorolytic"
FT                   /evidence="ECO:0000259|Pfam:PF03725"
SQ   SEQUENCE   261 AA;  28346 MW;  5E8CDF5293D46950 CRC64;
     MSGSEVISRL KRDYIYNLML KGEREDGRQF NELRDIALET GIIDKAEGSA MVQYGDTQVM
     VGVKMQVGTP FPDSPAEGVI ITSMELNPIA SPDFEAGPPR EKAIEMGRIV DRGIRESGAI
     DINKLCITEG EEVWMVFIDV HVLNNSGNIL DAASLGAIAA LMTTTVPSER EGKGEDYPMP
     VREMPVGVSL VKIGDEMVLD PTYGEESVCE TRITISSNQD GSICSMQKSG SGSLSPAQVV
     KASKIAKEKG EIIREKYLLE I
//