ID D3ZLC3_RAT Unreviewed; 1255 AA. AC D3ZLC3; DT 20-APR-2010, integrated into UniProtKB/TrEMBL. DT 20-APR-2010, sequence version 1. DT 10-JUN-2026, entry version 100. DE SubName: Full=ITPR interacting domain containing 2 {ECO:0000313|Ensembl:ENSRNOP00000008046.5}; GN Name=Itprid2 {ECO:0000313|Ensembl:ENSRNOP00000008046.5, GN ECO:0000313|RGD:1310767}; Synonyms=Ssfa2 {ECO:0000313|RGD:1310767}; OS Rattus norvegicus (Rat). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Rattus. OX NCBI_TaxID=10116 {ECO:0000313|Ensembl:ENSRNOP00000008046.5, ECO:0000313|Proteomes:UP000002494}; RN [1] {ECO:0007829|PubMed:22673903} RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=22673903; RA Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C., RA Olsen J.V.; RT "Quantitative maps of protein phosphorylation sites across 14 different rat RT organs and tissues."; RL Nat. Commun. 3:876-876(2012). RN [2] {ECO:0000313|Ensembl:ENSRNOP00000008046.5} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000008046.5}; RA Doris P.A., Kalbfleisch T., Li K., Howe K., Wood J.; RT "GRCr8: a new rat reference genome assembly contstructed from accurate long RT reads and long range scaffolding."; RL Submitted (JAN-2024) to the EMBL/GenBank/DDBJ databases. RN [3] {ECO:0000313|Ensembl:ENSRNOP00000008046.5} RP IDENTIFICATION. RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000008046.5}; RG Ensembl; RL Submitted (JAN-2026) to UniProtKB. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR RefSeq; NP_001101208.1; NM_001107738.1. DR AlphaFoldDB; D3ZLC3; -. DR FunCoup; D3ZLC3; 984. DR STRING; 10116.ENSRNOP00000008046; -. DR PaxDb; 10116-ENSRNOP00000008046; -. DR PeptideAtlas; D3ZLC3; -. DR Ensembl; ENSRNOT00000008046.8; ENSRNOP00000008046.5; ENSRNOG00000005865.9. DR GeneID; 311146; -. DR KEGG; rno:311146; -. DR AGR; RGD:1310767; -. DR CTD; 6744; -. DR RGD; 1310767; Itprid2. DR eggNOG; ENOG502QSG8; Eukaryota. DR GeneTree; ENSGT00940000158532; -. DR HOGENOM; CLU_007016_0_0_1; -. DR OMA; PGTPPMH; -. DR OrthoDB; 81283at9989; -. DR Proteomes; UP000002494; Chromosome 3. DR Bgee; ENSRNOG00000005865; Expressed in jejunum and 18 other cell types or tissues. DR ExpressionAtlas; D3ZLC3; baseline and differential. DR GO; GO:0005829; C:cytosol; ISO:RGD. DR GO; GO:0051015; F:actin filament binding; ISO:RGD. DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro. DR InterPro; IPR029325; ITPR-bd. DR InterPro; IPR029326; SSFA2_C. DR InterPro; IPR043444; TESPA1-like. DR PANTHER; PTHR17469:SF11; PROTEIN ITPRID2; 1. DR PANTHER; PTHR17469; SPERM SPECIFIC ANTIGEN 2-RELATED; 1. DR Pfam; PF14722; KRAP_IP3R_bind; 1. DR Pfam; PF14723; SSFA2_C; 1. DR SMART; SM01257; KRAP_IP3R_bind; 1. PE 1: Evidence at protein level; KW Reference proteome {ECO:0000313|Proteomes:UP000002494}. FT REGION 28..68 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 272..291 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 309..429 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 533..564 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 595..632 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 1091..1136 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 1149..1181 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 36..57 FT /note="Acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 357..372 FT /note="Low complexity" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 374..392 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 398..410 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 533..547 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 1106..1120 FT /note="Low complexity" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 1154..1164 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 1255 AA; 137191 MW; 03409140A92B915B CRC64; MNRPLSAEAE EELEWQVASR RRKAWAKCRS SWQASETEDL STETTTQDED EDDEEDLPGA KLPAAAGRGN VPNEKIAIWL KDCRTPLGAS LDEQSSVGPK GVLLRNGGSF EDDLSLGAEA NHLHEPDAQV ENCNNILAKE RRLQFHQKGR SMNSTGSGKS SGTVSSVSEL LELYEEDPEE ILYNLGFGRD EPDIASKIPS RFFNSSSFAR GIDIKVFLSA QMQRMEVENP NYALTSRFRQ IEVLTTVANA FSSLYSQVSG TPLQRIGSMS SVTSTKEAAD CPPPLTRSNT ANRLMKTLSK LNLCVDKTEK AEGSSTPAAE KGRSLSVSLS EDGGGGKSDP KPQKVIKKKE SSSMLATVTE EVSGSSSTIT DSIDADRLSD EAESNISHKV ESEENGEAHS QNDALRQSAV TDPDFGHDGG SMSSLCELES SSELKSAQAS SSEKEPCATL TIPSIRNIMV QQKDSFEMEE VQSTEGEAPH VPATCQLSLA KSKRDHLLRT ASQHSDSSGF AEDSTDCLSL NHLQVHESLQ AMGSSADSCD SETTVTSLGE DHVTPTAPDQ PYFNESEEES LASLQKGRAK VIVAEKRKAD NQDFPHCATA ENAGNNESVK GPCEPGPQIT ETETEEEPPL AATGELLREG SGESDMDKGS ECEFAQYTTH HILRSLTSFE EAQGSGMSSK KKTEFPSSVD RVNTALQRAQ MKVCSMSGQR VGRSLIKSKD LLKQRYFLAK AGYPLRRSQS LPTTLLSPVR VVSSVNVRLS PGKETRCSPP SFTYKYTPEE EQELEKQVTE HDGQSLVKST IFIPPSSVKK EEAPQSEGTR LEECHHGRLA PCPQFAPISQ STCSLHSVHS EWQDRPLCEH MRTLSAHSVP NISGAACSAF SSPFGCPYSH RHAAHPCRPC PVNPPSAIEM QLRRVLHDIR NSLQNLSQYP MTRGPDLAAA PYSTQKSSVL PLYENTFQEL QVVRRSLNLF RTQMMDLELA MLRQQTVVYP HMTEEDRYEV DQLQGLRNSV RMELQDLELQ LEERLLGLDE QLRAVRVPSP FRSSALPGMC GSRSADNLSC PSPLNVMEPV TELMREQSYL KSELGLSLGD MGYEIPPGES SESVFSQATS ESSSVCSSPS HTNRRSRGPS GSKPRARLVA RKKIFRASVA LTPTAPSRTG SVQTPPDLES SEEAGAAEEA SQVVGLTSHV EEEPEDLSLM PTAEEMHRNV EQDELQQVIR EIKESIVGEI RREIVSGLLA AVSSSKASAS KQDSH //